公开(公告)号：US20210115044A1

公开(公告)日：2021-04-22

申请号：US17048811

申请日：2019-04-22

申请人： Merck Sharp & Dohme Corp.

发明人： Tao Yu ,  James M. Apgar ,  Alan Whitehead ,  Yonglian Zhang ,  Zhiyong Hu ,  Valerie W. Shurtleff ,  John A. McCauley ,  Izzat T. Raheem

IPC分类号： C07D471/16 ,  A61K31/4985 ,  A61P31/18 ,  A61K31/52 ,  A61K31/435 ,  A61K31/5383 ,  A61K31/506 ,  A61K31/513 ,  A61K31/685 ,  A61K31/427

摘要： The present invention relates to Tricyclic Heterocycle Compounds of Formula (I): (I) and pharmaceutically acceptable salts or prodrug thereof, wherein R1, R2, R3, R4, R5, R6 and n are as defined herein. The present invention also relates to compositions comprising at least one Tricyclic Heterocycle Compound, and methods of using the Tricyclic Heterocycle Compounds for treating or preventing HIV infection in a subject.