公开(公告)号：US12091405B2

公开(公告)日：2024-09-17

申请号：US17287256

申请日：2019-10-28

申请人： Merck Sharp & Dohme LLC

发明人： Dane Clausen ,  Xavier Fradera ,  Liangqin Guo ,  Yongxin Han ,  Shuwen He ,  Joseph Kozlowski ,  Guoqing Li ,  Theodore A. Martinot ,  Alexander Pasternak ,  David Sloman ,  Li Xiao ,  Wensheng Yu ,  Rui Zhang

IPC分类号： C07D413/14 ,  C07D401/14

CPC分类号： C07D413/14 ,  C07D401/14

摘要： Disclosed herein are compounds of formula (I) which are inhibitors of an IDO enzyme: (I). Also disclosed herein are uses of the compounds in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising these compounds. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.