公开(公告)号：US20230312887A1

公开(公告)日：2023-10-05

申请号：US18022570

申请日：2021-09-08

Applicant: Merck Sharp & Dohme LLC ,  Werthenstein BioPharma GMBH

Inventor： David J. Lamberto ,  Paolo Avalle ,  Lorenzo Codan ,  Patrick Larpent ,  Jochen Schoell ,  Jeffrey S. Neuhaus

IPC: C08L5/16 ,  C08B37/16

CPC classification number: C08L5/16 ,  C08B37/0012

Abstract: The present invention relates to a process for drying crystalline sugammadex to meet solvent specifications that is independent of API crystallinity or crystalline form generated. It further relates to use of sugammadex in the reversal of neuromuscular blockade induced by recuronium bromide or by vecuronium bromide in adults undergoing surgery.