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公开(公告)号:US20250066489A1
公开(公告)日:2025-02-27
申请号:US18949107
申请日:2024-11-15
Applicant: Mersana Therapeutics, Inc.
Inventor: Natalya D. BODYAK , Michael J. DEVIT , Eric M. KRAULAND , Timothy B. LOWINGER , Peter U. PARK , Bianka PRINZ , Aleksandr V. YURKOVETSKIY
Abstract: This invention provides fully human monoclonal antibodies that recognize HER2. The invention further provides methods of using such monoclonal antibodies in a variety of therapeutic, diagnostic, and prophylactic indications.
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公开(公告)号:US20230265197A1
公开(公告)日:2023-08-24
申请号:US18049793
申请日:2022-10-26
Applicant: Mersana Therapeutics, Inc.
Inventor: Natalya D. BODYAK , Michael J. DEVIT , Eric M. KRAULAND , Timothy B. LOWINGER , Peter U. PARK , Bianka PRINZ , Aleksandr V. YURKOVETSKIY
CPC classification number: C07K16/2863 , C07K16/32 , C07K16/30 , A61K38/08 , A61K45/06 , A61K47/6803 , A61K47/6855 , A61K47/6883 , A61K47/6851 , C07K2317/21 , C07K2317/76 , C07K2317/565 , A61K2039/505
Abstract: This invention provides fully human monoclonal antibodies that recognize HER2. The invention further provides methods of using such monoclonal antibodies in a variety of therapeutic, diagnostic, and prophylactic indications.
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公开(公告)号:US20170266311A1
公开(公告)日:2017-09-21
申请号:US15457574
申请日:2017-03-13
Applicant: Mersana Therapeutics, Inc.
Inventor: Donald A. BERGSTROM , Natalya D. BODYAK , Timothy B. LOWINGER , Peter U. PARK , Laura L. POLING , Aleksandr V. YURKOVETSKIY
CPC classification number: C07K16/3023 , A61K47/6805 , A61K47/6811 , A61K47/6851 , A61K47/6857 , A61K47/6869 , A61K47/6883 , C07K16/3069 , C07K16/32 , C07K2317/21 , C07K2317/24 , C07K2317/565
Abstract: This disclosure provides NaPi2b-targeted antibody-drug conjugates (e.g., NaPi2b-targeted antibody-polymer-drug conjugates) that specifically bind to the extracellular region of SLC34A2, and to methods of using such conjugates in a variety of therapeutic, diagnostic, and prophylactic indications.
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公开(公告)号:US20210301031A1
公开(公告)日:2021-09-30
申请号:US17153711
申请日:2021-01-20
Applicant: Mersana Therapeutics, Inc.
Inventor: Donald A. BERGSTROM , Natalya D. BODYAK , Timothy B. LOWINGER , Peter U. PARK , Laura L. POLING , Aleksandr V. YURKOVETSKIY
Abstract: This disclosure provides NaPi2b-targeted antibody-drug conjugates (e.g., NaPi2b-targeted antibody-polymer-drug conjugates) that specifically bind to the extracellular region of SLC34A2, and to methods of using such conjugates in a variety of therapeutic, diagnostic, and prophylactic indications.
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公开(公告)号:US20170313778A1
公开(公告)日:2017-11-02
申请号:US15650429
申请日:2017-07-14
Applicant: Mersana Therapeutics, Inc.
Inventor: Natalya D. BODYAK , Michael J. DeVIT , Eric M. KRAULAND , Timothy B. LOWINGER , Peter U. PARK , Bianka PRINZ , Aleksandr V. YURKOVETSKIY
CPC classification number: C07K16/2863 , A61K38/08 , A61K45/06 , A61K47/6803 , A61K47/6851 , A61K47/6855 , A61K47/6883 , A61K2039/505 , A61K2039/507 , C07K16/30 , C07K16/32 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/565 , C07K2317/732 , C07K2317/76 , C07K2317/77 , C07K2317/92
Abstract: This invention provides fully human monoclonal antibodies that recognize HER2. The invention further provides methods of using such monoclonal antibodies in a variety of therapeutic, diagnostic, and prophylactic indications.
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公开(公告)号:US20200031941A1
公开(公告)日:2020-01-30
申请号:US16591394
申请日:2019-10-02
Applicant: Mersana Therapeutics, Inc.
Inventor: Natalya D. BODYAK , Michael J. DeVIT , Eric M. KRAULAND , Timothy B. LOWINGER , Peter U. PARK , Bianka PRINZ , Aleksandr V. YURKOVETSKIY
Abstract: This invention provides fully human monoclonal antibodies that recognize HER2. The invention further provides methods of using such monoclonal antibodies in a variety of therapeutic, diagnostic, and prophylactic indications.
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