公开(公告)号：US20140128439A1

公开(公告)日：2014-05-08

申请号：US13961848

申请日：2013-08-07

申请人： Metabolex, Inc.

发明人： Brian Edward Lavan ,  Gopal Chandra Saha ,  Brian K. Roberts ,  Charles A. McWerther

IPC分类号： C07C59/68 ,  A61K31/426 ,  A61K31/192 ,  C07C233/47 ,  A61K31/216

CPC分类号： A61K31/216 ,  A61K31/192 ,  A61K31/426 ,  C07C59/68 ,  C07C233/47

摘要： Methods of treating gout flares comprising administering a composition comprising a first urate-lowering agent are disclosed. In some aspects, the first urate-lowering agent is (−)-halofenate, (−)-halofenic acid, or a pharmaceutically acceptable salt thereof. Other aspects provide for methods of reducing the number, duration, frequency or intensity of gout flares experienced by a subject.