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公开(公告)号：US20210177785A1
公开(公告)日：2021-06-17
申请号：US17184808
申请日：2021-02-25
发明人： Shawn Baier , Naji Abumrad , Emily Harris
摘要： The present invention provides a composition comprising HMB. Methods of administering HMB to an animal are also described. HMB is administered to enhance recovery from soft tissue trauma, including both acute and non-acute soft tissue trauma. Enhanced recovery includes reduced recovery time and enhanced soft tissue healing. Soft tissue trauma includes administration of a Botulinum toxin, such as Botox. Administration of HMB in association with administration of a Botulinum toxin increases muscle strength and/or function in muscle, including adjacent and/or contralateral muscles and prevents or lessens loss of contractile material.
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公开(公告)号：US10682363B2
公开(公告)日：2020-06-16
申请号：US16230375
申请日：2018-12-21
发明人： John Rathmacher , John Fuller, Jr. , Shawn Baier , Steve Nissen , Naji Abumrad
IPC分类号： A61K31/59 , A61K31/19 , A23K20/00 , A23K20/174 , A23L33/00 , A23L33/10 , A23L33/15 , A23L33/155 , A23L33/175 , A61K31/593
摘要： The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D and HMB are administered to increase muscle mass, strength, and functionality. The combination of Vitamin D and HMB together has a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.
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公开(公告)号：US10092590B2
公开(公告)日：2018-10-09
申请号：US14023162
申请日：2013-09-10
发明人： Shawn Baier , Larry Kolb , John Rathmacher
IPC分类号： A61K31/7076 , A61K31/19
摘要： The present invention provides a composition comprising HMB and ATP. Methods of administering HMB and ATP to an animal are also described. HMB and ATP are administered to increase power and strength. The combination of HMB and ATP together has a synergistic effect, which results in a surprising and unexpected level of improvement in power and strength. HMB and ATP are also administered to increase lean body mass and muscle hypertrophy and to prevent typical declines in performance that are characteristic of overreaching.
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公开(公告)号：US20160074348A1
公开(公告)日：2016-03-17
申请号：US14861728
申请日：2015-09-22
发明人： John Rathmacher , John Fuller, JR. , Shawn Baier , Steve Nissen , Naji Abumrad
CPC分类号： A61K31/59 , A23K20/00 , A23K20/174 , A23L33/10 , A23L33/15 , A23L33/155 , A23L33/16 , A23L33/175 , A23L33/30 , A23V2002/00 , A61K9/0053 , A61K9/48 , A61K31/19 , A61K31/593 , A61K2300/00 , A23V2250/71 , A23V2200/316
摘要： The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D and HMB are administered to increase muscle mass, strength, and functionality. The combination of Vitamin D and HMB together has a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.
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5.发明申请Liquids and Foodstuffs Containing beta-hydroxy-beta-methylbutyrate (HMB) in the Free Acid Form and Methods of Manufacturing or Producing the Same 审中-公开含有游离酸形式的β-羟基-β-甲基丁酸酯（HMB）的液体和食品及其制造方法或生产方法公开(公告)号：US20140272000A1
公开(公告)日：2014-09-18
申请号：US14209614
申请日：2014-03-13
发明人： Shawn Baier , John Rathmacher , Joceylyn Seda
摘要： Liquids, substantially clear liquids and foodstuffs are described that contain free acid HMB. The liquids, substantially clear liquids and foodstuffs are substantially free of crude fat and may contain soluble proteins, carbohydrates, vitamins, minerals, amino acids, flavorings and other components. The products are shelf-stable and are substantially free of separation, gelation, sedimentation and coagulation.
摘要翻译： 描述了含有游离酸HMB的液体，基本上清澈的液体和食品。 液体，基本上透明的液体和食品基本上不含粗脂肪，并且可含有可溶性蛋白质，碳水化合物，维生素，矿物质，氨基酸，调味剂和其它组分。 产品是稳定的并且基本上没有分离，凝胶化，沉淀和凝结。
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公开(公告)号：US20210023096A1
公开(公告)日：2021-01-28
申请号：US16897945
申请日：2020-06-10
发明人： John Rathmacher , John Fuller, Jr. , Shawn Baier , Steve Nissen , Naji Abumrad
IPC分类号： A61K31/59 , A61K31/19 , A23K20/00 , A23K20/174 , A23L33/00 , A23L33/10 , A23L33/15 , A23L33/155 , A23L33/175 , A61K31/593
摘要： The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D and HMB are administered to increase muscle mass, strength, and functionality. The combination of Vitamin D and HMB together has a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.
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公开(公告)号：US10758504B2
公开(公告)日：2020-09-01
申请号：US15267717
申请日：2016-09-16
发明人： Shawn Baier , Naji Abumrad , Emily Harris
摘要： The present invention provides a composition comprising HMB. Methods of administering HMB to an animal are also described. HMB is administered to enhance recovery from soft tissue trauma, including both acute and non-acute soft tissue trauma. Enhanced recovery includes reduced recovery time and enhanced soft tissue healing.
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8.发明申请COMPOSITIONS AND METHODS OF USE OF ß-HYDROXY-ß-METHYLBUTYRATE (HMB) FOR ENHANCING RECOVERY FROM SOFT TISSUE TRAUMA 审中-公开使用β-羟基-β-甲基丁酸酯（HMB）的组合物和方法用于增强软组织TRAUMA的恢复公开(公告)号：US20170071886A1
公开(公告)日：2017-03-16
申请号：US15267717
申请日：2016-09-16
发明人： Shawn Baier , Naji Abumrad , Emily Harris
IPC分类号： A61K31/19
摘要： The present invention provides a composition comprising HMB. Methods of administering HMB to an animal are also described. HMB is administered to enhance recovery from soft tissue trauma, including both acute and non-acute soft tissue trauma. Enhanced recovery includes reduced recovery time and enhanced soft tissue healing.
摘要翻译： 本发明提供了包含HMB的组合物。 还描述了向动物施用HMB的方法。 施用HMB以增强从软组织创伤的恢复，包括急性和非急性软组织创伤。 增强的恢复包括减少恢复时间和增强的软组织愈合。
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公开(公告)号：US09539224B2
公开(公告)日：2017-01-10
申请号：US14861728
申请日：2015-09-22
发明人： John Rathmacher , John Fuller, Jr. , Shawn Baier , Steve Nissen , Naji Abumrad
IPC分类号： A61K31/19 , A61K31/59 , A23L33/15 , A23L33/175 , A23K20/174 , A23K20/00 , A61K31/593 , A23L33/155 , A23L33/10 , A61K9/00
CPC分类号： A61K31/59 , A23K20/00 , A23K20/174 , A23L33/10 , A23L33/15 , A23L33/155 , A23L33/16 , A23L33/175 , A23L33/30 , A23V2002/00 , A61K9/0053 , A61K9/48 , A61K31/19 , A61K31/593 , A61K2300/00 , A23V2250/71 , A23V2200/316
摘要： The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D and HMB are administered to increase muscle mass, strength, and functionality. The combination of Vitamin D and HMB together has a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.
摘要翻译： 本发明提供包含HMB和维生素D的组合物。还描述了向动物施用HMB和维生素D的方法。 施用维生素D和HMB以增加肌肉质量，强度和功能。 维生素D和HMB的组合一起具有协同效应，这导致肌肉质量，强度和功能性的惊人和意想不到的改善水平。
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公开(公告)号：US11547713B2
公开(公告)日：2023-01-10
申请号：US16897945
申请日：2020-06-10
发明人： John Rathmacher , John Fuller, Jr. , Shawn Baier , Steve Nissen , Naji Abumrad
IPC分类号： A61K31/59 , A61K31/19 , A23K20/00 , A23K20/174 , A23L33/00 , A23L33/10 , A23L33/15 , A23L33/155 , A23L33/175 , A61K31/593
摘要： The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D and HMB are administered to increase muscle mass, strength, and functionality. The combination of Vitamin D and HMB together has a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.
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