公开(公告)号：US20230053455A1

公开(公告)日：2023-02-23

申请号：US17791460

申请日：2021-01-29

申请人： Metriopharm AG

发明人： Wolfgang Brysch ,  Astrid Kaiser ,  Petra Schulz ,  Sara Schumann ,  Jörg von Wegerer

IPC分类号： A61K31/502 ,  A61P11/00

摘要： The present invention relates to the use of 5-amino-2,3-dihydro-1,4-phthalazinedione or one of its pharmaceutically acceptable salts in the treatment of rare chronic inflammatory pulmonary diseases. The invention in particular relates to the use of 5-amino-2,3-dihydro-1,4-phthalazinedione sodium salt for said purposes.

公开(公告)号：US20230113516A1

公开(公告)日：2023-04-13

申请号：US17913687

申请日：2021-03-24

申请人： Metriopharm AG

发明人： Wolfgang Brysch ,  Astrid Kaiser ,  Petra Schulz ,  Sara Schumann ,  Jörg von Wegerer ,  Christian Setz ,  Ulrich Schubert

IPC分类号： A61K31/502 ,  A61K45/06 ,  A61P11/00

摘要： The present invention relates to the use of 5-amino-2,3-dihydro-1,4-phthalazinedione or one of its pharmaceutically acceptable salts in the prevention or treatment of acute lung injury. The invention in particular relates to the use of 5-amino-2, 3-dihydro-1,4-phthalazinedione sodium salt for said purposes.

公开(公告)号：US20230061223A1

公开(公告)日：2023-03-02

申请号：US17795360

申请日：2021-01-29

申请人： MetrioPharm AG

发明人： Wolfgang Brysch ,  Astrid Kaiser ,  Petra Schulz ,  Sara Schumann ,  Jörg von Wegerer

IPC分类号： A61K9/00 ,  A61P11/00 ,  A61K31/502 ,  A61M11/00

摘要： The present invention relates to the use of 5-amino-2,3-dihydro-1,4-phthalazinedione or its pharmaceutically acceptable N salts in the inhalatory treatment of inflammatory pulmonary diseases. The invention in particular relates to the use of 5-amino-2,3-dihydro-1,4-phthalazinedione sodium salt for said purposes. Advantageous features of an aerosol containing 5-amino-2,3-dihydro-1,4-phthalazinedione or its pharmaceutically acceptable salts and a method for producing said aerosol are disclosed. The present invention further relates to a kit for inhalatory treatment of inflammatory pulmonary diseases.