公开(公告)号：US20110127413A1

公开(公告)日：2011-06-02

申请号：US12628259

申请日：2009-12-01

申请人： Michael E. Casey ,  Mu Chen ,  Timothy G. Gremillion ,  Charles H. Hayden, JR. ,  Mark W. Lenox ,  Vladimir Y. Panin

发明人： Michael E. Casey ,  Mu Chen ,  Timothy G. Gremillion ,  Charles H. Hayden, JR. ,  Mark W. Lenox ,  Vladimir Y. Panin

IPC分类号： G12B13/00

CPC分类号： G12B13/00 ,  G01T1/2985

摘要： A representative positron emission tomography (PET) calibration system includes a PET scanner having a ring detector, a phantom that is placed at approximately the center of the ring detector, and a time alignment calibration manager that is coupled to the PET scanner. The time alignment calibration manager detects coincidence events from the phantom, calculates position of time of flight events from the ring detector based on the detected coincidence events, and calculates time offsets for the ring detector using a mean value calculation based on the calculated position of the time of flight events.

摘要翻译： 代表性的正电子发射断层摄影（PET）校准系统包括具有环检测器的PET扫描器，放置在环检测器的大约中心处的体模，以及耦合到PET扫描器的时间对准校准管理器。 时间校准管理器检测来自幻影的重合事件，基于检测到的重合事件来计算来自环形探测器的飞行时间的位置，并使用基于计算出的位置的计算的平均值计算环形探测器的时间偏移量 飞行时间事件

公开(公告)号：US08089043B2

公开(公告)日：2012-01-03

申请号：US12628259

申请日：2009-12-01

申请人： Michael E. Casey ,  Mu Chen ,  Timothy G. Gremillion ,  Charles H. Hayden, Jr. ,  Mark W. Lenox ,  Vladimir Y. Panin

发明人： Michael E. Casey ,  Mu Chen ,  Timothy G. Gremillion ,  Charles H. Hayden, Jr. ,  Mark W. Lenox ,  Vladimir Y. Panin

IPC分类号： G01D18/00

CPC分类号： G12B13/00 ,  G01T1/2985

摘要： A representative positron emission tomography (PET) calibration system includes a PET scanner having a ring detector, a phantom that is placed at approximately the center of the ring detector, and a time alignment calibration manager that is coupled to the PET scanner. The time alignment calibration manager detects coincidence events from the phantom, calculates position of time of flight events from the ring detector based on the detected coincidence events, and calculates time offsets for the ring detector using a mean value calculation based on the calculated position of the time of flight events.

摘要翻译： 代表性的正电子发射断层摄影（PET）校准系统包括具有环检测器的PET扫描器，放置在环检测器的大约中心处的体模，以及耦合到PET扫描器的时间对准校准管理器。 时间校准管理器检测来自幻影的重合事件，基于检测到的重合事件来计算来自环形探测器的飞行时间的位置，并使用基于计算出的位置的计算的平均值计算环形探测器的时间偏移量 飞行时间事件

公开(公告)号：US20090074152A1

公开(公告)日：2009-03-19

申请号：US12204180

申请日：2008-09-04

申请人： Mu Chen ,  Michael E. Casey

发明人： Mu Chen ,  Michael E. Casey

IPC分类号： G01D18/00 ,  G01N37/00

CPC分类号： G01T1/169 ,  G01T1/1648

摘要： A method for determining quality of sinograms produced by a medical imaging device. The method may include placing a uniform phantom object in the field of view of the medical imaging device; acquiring one or more phantom sinograms of the uniform phantom object; establish a set of parameters for the acquired one or more phantom sinograms; and determine, based on pre-set ranges of the parameters, the quality of sinograms produced by the medical imaging device. The parameters may be one or more parameters of a group of parameters consisting of block uniformity, block efficiency, randoms rate, scanner efficiency, and scatter ratio.

摘要翻译： 一种用于确定由医学成像装置产生的正弦图的质量的方法。 该方法可以包括在医疗成像设备的视野中放置均匀的体模对象; 获取统一幻影物体的一个或多个幻像正弦图; 为所获得的一个或多个幻像正弦图建立一组参数; 并且基于参数的预设范围来确定由医学成像装置产生的正弦图的质量。 参数可以是由块均匀性，块效率，随机速率，扫描仪效率和散射比组成的一组参数的一个或多个参数。

公开(公告)号：US20090072152A1

公开(公告)日：2009-03-19

申请号：US12034095

申请日：2008-02-20

申请人： Mu Chen ,  Michael E. Casey ,  Jun Bao

发明人： Mu Chen ,  Michael E. Casey ,  Jun Bao

IPC分类号： G01T1/164

CPC分类号： G01T7/005

摘要： A calibration system for a combined Positron Emission Tomography (PET)/Computed Tomography scanner system, may have a support structure carrying a rotation motor driving a phantom, wherein the phantom has at least two phantom rods and the rods are positioned such that they are neither parallel nor connected to each other.

摘要翻译： 用于组合正电子发射断层扫描（PET）/计算机断层摄影扫描仪系统的校准系统可以具有承载驱动模体的旋转马达的支撑结构，其中，模体具有至少两个幻影棒，并且杆被定位成使得它们不是 平行或相互连接。

公开(公告)号：US07890282B2

公开(公告)日：2011-02-15

申请号：US12212457

申请日：2008-09-17

申请人： Mu Chen ,  Vladimir Panin ,  Michael E. Casey

发明人： Mu Chen ,  Vladimir Panin ,  Michael E. Casey

IPC分类号： G01D18/00

CPC分类号： G01T1/2985 ,  A61B6/037 ,  G01T7/005

摘要： The present invention provides a method for estimating crystal efficiency in a PET detector that takes axial compression into account. It does so via an iterative methodology in which a μ-map is first generated and then is used to obtain a solution for the equation L ⁡ ( ɛ i ) = ∑ n ∈ N ⁢ ⁢ y n ⁢ log ⁢ ∑ i , j ∈ span ⁢ ⁢ g ij ⁢ ɛ i ⁢ ɛ j ⁢ x ij - ∑ i , j ∈ span ⁢ ⁢ g ij ⁢ ɛ i ⁢ ɛ j ⁢ x ij , wherein gij is a geometric factor for LOR(i,j), εi and εj are the efficiencies for crystal i and crystal j, and xij is the line integral of the source distribution along LOR(i,j). Once efficiencies are determined, they are used to calibrate the PET detector.

摘要翻译： 本发明提供了在考虑轴向压缩的PET检测器中估计晶体效率的方法。 它通过迭代方法来实现，其中首先生成μ映射，然后用于获得等式的解。⁡（∈i）=Σn∈N⁢n n nΣΣΣ，∈∈∈ 其中gij是LOR（i，j），＆egr的几何因子，其中gij是LOR（i，j）的几何因子，eij; i和＆egr; j是晶体i和晶体j的效率，xij是沿LOR（i，j）的源分布的线积分。 一旦确定效率，它们被用于校准PET检测器。

公开(公告)号：US06963065B2

公开(公告)日：2005-11-08

申请号：US10418520

申请日：2003-04-18

申请人： Maurizio Conti ,  James J. Hamill ,  Michael E. Casey ,  Mu Chen

发明人： Maurizio Conti ,  James J. Hamill ,  Michael E. Casey ,  Mu Chen

IPC分类号： G01D18/00 ,  G01T1/172 ,  G01T1/29 ,  G12B13/00

CPC分类号： G01T1/2985 ,  A61B6/037

摘要： A normalization apparatus and method for a PET scanner with panel detectors for obtaining an estimate of a normalization array, for correction for count rate effects on the normalization array, and for measurement of the relation between the normalization array and the count rate. The method of the present invention is based on two quasi-independent radial and axial components, which are count rate dependent due to sensitivity changes across the detector blocks. A scatter source is disposed at the center of the FOV and a scatter-free source is disposed at the outer edge of the FOV. The method computes the normalization array through several steps which evaluate the geometric profile, the axial profile, and the correction factor. A count rate correction is introduced to extend the normalization array to any count rate.

摘要翻译： 一种具有面板检测器的PET扫描仪的归一化装置和方法，用于获得归一化阵列的估计，用于校正对归一化阵列的计数率影响，以及用于测量归一化阵列与计数率之间的关系。 本发明的方法是基于两个准独立的径向和轴向分量，其由于检测器块两端的灵敏度变化而依次计数。 散射源设置在FOV的中心，并且不分散源设置在FOV的外边缘处。 该方法通过评估几何轮廓，轴向轮廓和校正因子的几个步骤来计算归一化阵列。 引入计数率校正以将归一化数组扩展到任何计数率。

公开(公告)号：US07858943B2

公开(公告)日：2010-12-28

申请号：US12204180

申请日：2008-09-04

申请人： Mu Chen ,  Michael E. Casey

发明人： Mu Chen ,  Michael E. Casey

IPC分类号： G01D18/00

CPC分类号： G01T1/169 ,  G01T1/1648

摘要： A method for determining quality of sinograms produced by a medical imaging device. The method may include placing a uniform phantom object in the field of view of the medical imaging device; acquiring one or more phantom sinograms of the uniform phantom object; establish a set of parameters for the acquired one or more phantom sinograms; and determine, based on pre-set ranges of the parameters, the quality of sinograms produced by the medical imaging device. The parameters may be one or more parameters of a group of parameters consisting of block uniformity, block efficiency, randoms rate, scanner efficiency, and scatter ratio.

摘要翻译： 一种用于确定由医学成像装置产生的正弦图的质量的方法。 该方法可以包括在医疗成像设备的视野中放置均匀的体模对象; 获取统一幻影物体的一个或多个幻像正弦图; 为所获得的一个或多个幻像正弦图建立一组参数; 并且基于参数的预设范围来确定由医学成像装置产生的正弦图的质量。 参数可以是由块均匀性，块效率，随机速率，扫描器效率和散射比组成的一组参数的一个或多个参数。

公开(公告)号：US20090072131A1

公开(公告)日：2009-03-19

申请号：US12212457

申请日：2008-09-17

申请人： Mu Chen ,  Vladimir Panin ,  Michael E. Casey

发明人： Mu Chen ,  Vladimir Panin ,  Michael E. Casey

IPC分类号： G01D18/00

CPC分类号： G01T1/2985 ,  A61B6/037 ,  G01T7/005

摘要： The present invention provides a method for estimating crystal efficiency in a PET detector that takes axial compression into account. It does so via an iterative methodology in which a μ-map is first generated and then is used to obtain a solution for the equation L  ( ɛ i ) = ∑ n ∈ N   y n  log  ∑ i , j ∈ span   g ij  ɛ i  ɛ j  x ij - ∑ i , j ∈ span   g ij  ɛ i  ɛ j  x ij , wherein gij is a geometric factor for LOR(i,j), εi and εj are the efficiencies for crystal i and crystal j, and xij is the line integral of the source distribution along LOR(i,j). Once efficiencies are determined, they are used to calibrate the PET detector.

公开(公告)号：US07569829B2

公开(公告)日：2009-08-04

申请号：US12034095

申请日：2008-02-20

申请人： Mu Chen ,  Michael E. Casey ,  Jun Bao

发明人： Mu Chen ,  Michael E. Casey ,  Jun Bao

IPC分类号： G01T1/161 ,  G01T1/164 ,  G12B13/00

CPC分类号： G01T7/005

摘要： A calibration system for a combined Positron Emission Tomography (PET)/Computed Tomography scanner system, may have a support structure carrying a rotation motor driving a phantom, wherein the phantom has at least two phantom rods and the rods are positioned such that they are neither parallel nor connected to each other.

摘要翻译： 用于组合正电子发射断层扫描（PET）/计算机断层摄影扫描仪系统的校准系统可以具有承载驱动模体的旋转马达的支撑结构，其中，模体具有至少两个幻影棒，并且杆被定位成使得它们不是 平行或相互连接。

公开(公告)号：US20100080339A1

公开(公告)日：2010-04-01

申请号：US12568339

申请日：2009-09-28

申请人： Derek W. Austin ,  Mu Chen ,  Bing Feng ,  Robert A. Mintzer ,  Anne Smith

发明人： Derek W. Austin ,  Mu Chen ,  Bing Feng ,  Robert A. Mintzer ,  Anne Smith

IPC分类号： G06T1/00 ,  G06K9/00 ,  H05G1/60

CPC分类号： G06T11/006 ,  G06T2211/424 ,  G21K2207/00

摘要： A system and method for reconstructing single photon emission computed tomography data acquired with a pinhole collimator includes sub-dividing each voxel in the imaging target object space into sub-voxels and sub-dividing each of the detector bins in the gamma camera detector into sub-bins, connecting the centers of each of the sub-voxels to each of the detector sub-bins through a pinhole provided in the pinhole collimator by ray tracing and for each ray connecting the centers of each of the sub-voxels to each of the detector sub-bins, the transmission probability is calculated by analytically solving the intersections between the ray and the pinhole surfaces. Then, a geometric-response-function of the pinhole collimator is computed which is then convolved with the intrinsic-response-function of the detector to obtain the PSF.

摘要翻译： 用于重构用针孔准直器获取的单光子发射计算机断层摄影数据的系统和方法包括将成像目标对象空间中的每个体素划分成子体素，并且将伽马相机检测器中的每个检测器区块分割成子像素， 将每个子体素的中心连接到每个检测器子箱中，通过通过光线跟踪设置在针孔准直器中的针孔，以及将每个子体素的中心连接到每个检测器的每个射线 通过解析光线和针孔表面之间的交点来计算传输概率。 然后，计算针孔准直仪的几何响应函数，然后将其与检测器的内在响应函数进行卷积以获得PSF。