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    Apparatus for automatic calibration of PET/CT systems
    1.
    发明授权
    Apparatus for automatic calibration of PET/CT systems 有权
    PET / CT系统自动校准装置

    公开(公告)号：US07569829B2

    公开(公告)日：2009-08-04

    申请号：US12034095

    申请日：2008-02-20

    申请人： Mu Chen ,  Michael E. Casey ,  Jun Bao

    发明人： Mu Chen ,  Michael E. Casey ,  Jun Bao

    IPC分类号： G01T1/161 ,  G01T1/164 ,  G12B13/00

    CPC分类号： G01T7/005

    摘要： A calibration system for a combined Positron Emission Tomography (PET)/Computed Tomography scanner system, may have a support structure carrying a rotation motor driving a phantom, wherein the phantom has at least two phantom rods and the rods are positioned such that they are neither parallel nor connected to each other.

    摘要翻译： 用于组合正电子发射断层扫描（PET）/计算机断层摄影扫描仪系统的校准系统可以具有承载驱动模体的旋转马达的支撑结构，其中，模体具有至少两个幻影棒，并且杆被定位成使得它们不是 平行或相互连接。

    Apparatus For Automatic Calibration of PET/CT Systems
    2.
    发明申请
    Apparatus For Automatic Calibration of PET/CT Systems 有权
    PET / CT系统自动校准装置

    公开(公告)号：US20090072152A1

    公开(公告)日：2009-03-19

    申请号：US12034095

    申请日：2008-02-20

    申请人： Mu Chen ,  Michael E. Casey ,  Jun Bao

    发明人： Mu Chen ,  Michael E. Casey ,  Jun Bao

    IPC分类号： G01T1/164

    CPC分类号： G01T7/005

    摘要： A calibration system for a combined Positron Emission Tomography (PET)/Computed Tomography scanner system, may have a support structure carrying a rotation motor driving a phantom, wherein the phantom has at least two phantom rods and the rods are positioned such that they are neither parallel nor connected to each other.

    摘要翻译： 用于组合正电子发射断层扫描（PET）/计算机断层摄影扫描仪系统的校准系统可以具有承载驱动模体的旋转马达的支撑结构，其中，模体具有至少两个幻影棒，并且杆被定位成使得它们不是 平行或相互连接。

    High-powered optical module safety systems and methods
    3.
    发明授权
    High-powered optical module safety systems and methods 有权
    大功率光模块安全系统及方法

    公开(公告)号：US08817245B2

    公开(公告)日：2014-08-26

    申请号：US13593212

    申请日：2012-08-23

    申请人： Jean-Luc Archambault ,  Jun Bao

    发明人： Jean-Luc Archambault ,  Jun Bao

    IPC分类号： G01N21/00 ,  G01M11/00

    CPC分类号： G01M11/3145 ,  G01M11/335 ,  H01S3/0014 ,  H01S3/06754 ,  H01S3/094003 ,  H01S3/10007 ,  H01S3/1608 ,  H01S3/302

    摘要： A method, optical module, and optical amplifier are configured to detect fiber discontinuities at or near a port from which high powered optical signals are input into a fiber span. These fiber discontinuities can include fiber pinches, and are detected by monitoring for slight changes in a backscatter signal. Detection is quick and efficient based on the backscatter signal being attenuated by the fiber discontinuities twice, namely once as the high powered optical signals and again as the associated backscatter signal of the high powered optical signals returning to the port. Various remedial actions can be taken upon detecting fiber pinches at or near the port.

    摘要翻译： 一种方法，光学模块和光学放大器被配置为检测光纤不连续性，其中高功率光信号从该端口输入到光纤跨度。 这些光纤不连续性可以包括光纤夹紧，并通过监视反向散射信号的轻微变化来检测。 基于后向散射信号被光纤不连续性衰减两次，即一次作为高功率光信号，再次作为返回到端口的大功率光信号的相关后向散射信号，检测是快速和有效的。 在端口处或附近检测光纤夹点时可以采取各种补救措施。

    High-degree reconfigurable optical add-drop multiplexing systems using bi-directional wavelength selective switches
    4.
    发明授权
    High-degree reconfigurable optical add-drop multiplexing systems using bi-directional wavelength selective switches 有权
    使用双向波长选择开关的高度可重构光分插复用系统

    公开(公告)号：US08306425B2

    公开(公告)日：2012-11-06

    申请号：US12356593

    申请日：2009-01-21

    申请人： Xiaohui Yang ,  Zhonghua Zhu ,  Jun Bao

    发明人： Xiaohui Yang ,  Zhonghua Zhu ,  Jun Bao

    IPC分类号： H04J14/02 ,  H04J14/00

    CPC分类号： H04Q11/0005 ,  H04J14/0205 ,  H04J14/0206 ,  H04J14/0212 ,  H04J14/0213 ,  H04J14/0217 ,  H04J14/0219 ,  H04J14/0284 ,  H04Q2011/0035 ,  H04Q2011/0052

    摘要： The present disclosure provides high-degree reconfigurable optical add-drop multiplexing (ROADM) systems using bi-directional wavelength selective switches (WSSs) and optical circulators. A single WSS is utilized on each degree of a node in a bi-directional manner, i.e. both ingress and egress share the same WSS. Advantageously, the present invention eliminates conventional splitters/combiners thereby capping intra-node insertion loss to a certain value regardless of the number of degrees. More importantly, the present invention reduces noise penalty associated with high-degree nodes while minimizing cost.

    摘要翻译： 本公开提供使用双向波长选择开关（WSS）和光学循环器的高度可重构的光分插复用（ROADM）系统。 以双向方式在每个节点上使用单个WSS，即入口和出口共享相同的WSS。 有利地，本发明消除了常规的分离器/组合器，从而将节点内插入损耗限制到一定值，而不管度数。 更重要的是，本发明降低了与高度节点相关联的噪声，同时最小化了成本。

    Optical module manufacturing and testing systems and methods
    5.
    发明授权
    Optical module manufacturing and testing systems and methods 有权
    光模块制造和测试系统及方法

    公开(公告)号：US08233215B2

    公开(公告)日：2012-07-31

    申请号：US12542899

    申请日：2009-08-18

    申请人： Jun Bao

    发明人： Jun Bao

    IPC分类号： H04B10/08 ,  H04B10/17 ,  G02B6/46

    CPC分类号： H01S3/06704

    摘要： The present disclosure relates to streamlining optical module and/or subassembly development, manufacturing, and testing through introducing a memory component within a module and/or subassembly that is utilized with a host module for system calibration and/or configuration. In an exemplary embodiment, the present invention can streamline optical amplifier (EDFA) module and/or subassembly development, manufacturing, and testing. The present invention includes an optical module/sub-assembly without control circuitry, i.e. a “dumb module”, but with a memory that is used to load relevant data from a supplier. This data is utilized to calibrate, test, and configure the optical module/sub-assembly in a host module. The host module includes control circuitry to access this memory in the optical module/sub-assembly and to calibrate, test, configure, and control the optical module/sub-assembly. Advantageously, this additional memory reduces manufacturing time without the disadvantage of adding complexity in the optical module/sub-assembly.

    摘要翻译： 本公开涉及通过在与主机模块一起用于系统校准和/或配置的模块和/或子组件中引入存储器组件来简化光学模块和/或子组件开发，制造和测试。 在示例性实施例中，本发明可以简化光放大器（EDFA）模块和/或子组件开发，制造和测试。 本发明包括没有控制电路的光学模块/子组件，即“哑模块”，但是具有用于从供应商加载相关数据的存储器。 该数据用于校准，测试和配置主机模块中的光模块/子组件。 主机模块包括用于访问光学模块/子组件中的该存储器并且校准，测试，配置和控制光学模块/子组件的控制电路。 有利地，该附加存储器减少了制造时间，而没有增加光学模块/子组件的复杂性的缺点。

    Fusion Protein Inhibiting Osteoclast Formation, Preparation Method and Medicine Compositions Thereof
    6.
    发明申请
    Fusion Protein Inhibiting Osteoclast Formation, Preparation Method and Medicine Compositions Thereof 有权
    融合蛋白抑制破骨细胞形成，制备方法和药物组合物

    公开(公告)号：US20110243944A1

    公开(公告)日：2011-10-06

    申请号：US13123235

    申请日：2009-09-29

    申请人： Jun Bao ,  Haiming Chen ,  Daocheng Zhu

    发明人： Jun Bao ,  Haiming Chen ,  Daocheng Zhu

    IPC分类号： A61K39/395 ,  C07H21/04 ,  C07K19/00 ,  C12P21/02 ,  A61P19/08 ,  A61P19/10

    CPC分类号： C07K14/70575 ,  A61K38/00 ,  C07K2319/30

    摘要： The present invention provides a coding gene having the nucleic acid sequence shown as SEQ ID NO:1 and the fusion protein RIG (SEQ ID NO:2) that inhibits osteoclast formation. The present invention also provides the preparation method for the fusion protein RIG as well as synthetic oligo-nucleotide primers, plasmids and host cells used in the method and a medicine having the above fusion protein RIG as active ingredient. The fusion protein RIG in present invention is derived from humanized immunoglobulin and RANKL with a flexible hinge region. RIG can cross link the cell surface receptor RANK and Fcγ 1 to induce a cytosolic inhibitory signal leading to the inhibition of osteoclast formation. The fusion protein RIG in present invention can play an essential role in treating osteoporosis and bone resorption diseases caused by tumor metastasis.

    摘要翻译： 本发明提供具有SEQ ID NO：1所示的核酸序列和抑制破骨细胞形成的融合蛋白RIG（SEQ ID NO：2）的编码基因。 本发明还提供了融合蛋白RIG的制备方法以及该方法中使用的合成寡核苷酸引物，质粒和宿主细胞以及具有上述融合蛋白RIG作为活性成分的药物。 本发明的融合蛋白RIG衍生自具有柔性铰链区的人源化免疫球蛋白和RANKL。 RIG可以将细胞表面受体RANK和Fcγ1交联以诱导抑制破骨细胞形成的细胞溶质抑制信号。 本发明的融合蛋白RIG可以在治疗由肿瘤转移引起的骨质疏松症和骨吸收疾病中发挥重要作用。

    Systems and methods reducing coherence effect in narrow line-width light sources
    10.
    发明授权
    Systems and methods reducing coherence effect in narrow line-width light sources 有权
    系统和方法降低窄线宽光源的相干效应

    公开(公告)号：US09140624B2

    公开(公告)日：2015-09-22

    申请号：US13541146

    申请日：2012-07-03

    申请人： Jun Bao ,  Michael Haidar Shahine ,  Hua Jiao ,  Jean-Luc Archambault

    发明人： Jun Bao ,  Michael Haidar Shahine ,  Hua Jiao ,  Jean-Luc Archambault

    IPC分类号： G01N21/55 ,  G01M11/00

    CPC分类号： G01M11/3118 ,  G01N21/55

    摘要： Systems and methods are described for reducing coherence effect in narrow line-width light sources through various modulation techniques. The systems and methods can include a narrow line-width laser source with a thermoelectric cooler thermally coupled thereto and a controller communicatively coupled to the thermoelectric cooler. The controller is configured to provide a varied input signal to the thermoelectric cooler to reduce coherence of the narrow line-width laser source by artificially broadening the narrow line-width on a time averaged basis. The systems and methods can also include direct modulation of the narrow line-width laser source. The systems and methods can include a narrow line-width Optical Time Domain Reflectometer (OTDR). The systems and methods can also include direct modulation of the narrow line-width laser source with or without the varied input signal to the thermoelectric cooler.

    摘要翻译： 描述了通过各种调制技术降低窄线宽光源的相干效应的系统和方法。 该系统和方法可以包括具有热耦合到其上的热电冷却器的窄线宽激光源和通信地耦合到热电冷却器的控制器。 控制器被配置为向热电冷却器提供变化的输入信号，以通过以时间平均的方式人为地加宽窄线宽来减小窄线宽激光源的相干性。 系统和方法还可以包括对窄线宽激光源的直接调制。 系统和方法可以包括窄线宽光时域反射计（OTDR）。 这些系统和方法还可以包括对具有或不具有到热电冷却器的变化的输入信号的窄线宽激光源的直接调制。