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公开(公告)号：US08900202B2
公开(公告)日：2014-12-02
申请号：US13500416
申请日：2010-10-08
申请人： Michael Helmer , Claudia Matthias , Peter Nober , Reza Shahbazfar , Benjamin Schaefer , Leo Zeimetz
发明人： Michael Helmer , Claudia Matthias , Peter Nober , Reza Shahbazfar , Benjamin Schaefer , Leo Zeimetz
CPC分类号： A61M5/31515 , A61M5/24 , A61M5/3146 , A61M2005/2407 , A61M2207/00
摘要： The present invention relates to a drive mechanism for a drug delivery device for dispensing of a dose of a medicinal product, comprising: a holder for a product-containing cartridge, the cartridge having a piston slidably arranged therein in an axial direction, a piston rod to be operably engaged with the cartridge's piston for dispensing of a dose of the medicinal product, an adjusting assembly adapted to eliminate axial clearance between the piston and the piston rod, wherein the adjusting assembly comprises at least one radially extending spike element for mutually locking in position the piston and the piston rod irrespective of the relative distance between piston and piston rod.
摘要翻译： 本发明涉及一种药剂输送装置的驱动机构，用于分配药剂的剂量，其特征在于，包括：用于容纳产品的药筒的保持器，所述药筒具有沿轴向可滑动地设置的活塞，活塞杆 与药筒的活塞可操作地接合以分配一定剂量的药用产品，调节组件适于消除活塞和活塞杆之间的轴向间隙，其中调节组件包括至少一个径向延伸的尖钉元件，用于相互锁定 定位活塞和活塞杆，而不管活塞和活塞杆之间的相对距离如何。
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公开(公告)号：US20130023831A1
公开(公告)日：2013-01-24
申请号：US13500416
申请日：2010-10-08
申请人： Michael Helmer , Claudia Matthias , Peter Nober , Reza Shahbazfar , Benjamin Schaefer , Leo Zeimetz
发明人： Michael Helmer , Claudia Matthias , Peter Nober , Reza Shahbazfar , Benjamin Schaefer , Leo Zeimetz
IPC分类号： A61M5/315
CPC分类号： A61M5/31515 , A61M5/24 , A61M5/3146 , A61M2005/2407 , A61M2207/00
摘要： The present invention relates to a drive mechanism for a drug delivery device for dispensing of a dose of a medicinal product, comprising: a holder for a product-containing cartridge, the cartridge having a piston slidably arranged therein in an axial direction, a piston rod to be operably engaged with the cartridge's piston for dispensing of a dose of the medicinal product, an adjusting assembly adapted to eliminate axial clearance between the piston and the piston rod, wherein the adjusting assembly comprises at least one radially extending spike element for mutually locking in position the piston and the piston rod irrespective of the relative distance between piston and piston rod.
摘要翻译： 本发明涉及一种药剂输送装置的驱动机构，用于分配药剂的剂量，其特征在于，包括：用于容纳产品的药筒的保持器，所述药筒具有沿轴向可滑动地设置的活塞，活塞杆 与药筒的活塞可操作地接合以分配一定剂量的药用产品，调节组件适于消除活塞和活塞杆之间的轴向间隙，其中调节组件包括至少一个径向延伸的尖钉元件，用于相互锁定 定位活塞和活塞杆，而不管活塞和活塞杆之间的相对距离如何。
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公开(公告)号：US20130338600A1
公开(公告)日：2013-12-19
申请号：US14002179
申请日：2012-03-16
申请人： Michael Helmer , Claudia Matthias , Lutz Mueller , Steffen Raab , Peter Nober , Reza Shahbazfar , Benjamin Schäfer , Leo Zeimetz
发明人： Michael Helmer , Claudia Matthias , Lutz Mueller , Steffen Raab , Peter Nober , Reza Shahbazfar , Benjamin Schäfer , Leo Zeimetz
IPC分类号： A61M5/31
CPC分类号： A61M5/31 , A61M5/24 , Y10T29/49826
摘要： A drug delivery device for dispensing of a dose of a medicinal product is presented comprising a first housing component having a receptacle being oval- or elliptically shaped in radial cross section and being adapted to at least partially receive an insert portion of a second housing component being at least partially insertable into said first housing component along an axial direction, wherein the insert portion is oval- or elliptically shaped in radial cross section. The outside dimension or an at least one outside diameter of the insert portion is at least in sections larger than a corresponding inner dimension or an at least one inner diameter of the receptacle and wherein the insert portion and the receptacle are adapted to generate a radially acting mutual clamping of first and second housing components in a pre-fixing assembly configuration.
摘要翻译： 提供了一种用于分配药物产品剂量的药物递送装置，其包括第一壳体部件，所述第一壳体部件具有椭圆形或椭圆形的径向横截面并且适于至少部分地容纳第二壳体部件的插入部分， 至少部分地沿着轴向方向插入所述第一壳体部件中，其中所述插入部分在径向横截面上呈椭圆形或椭圆形。 插入部分的外部尺寸或至少一个外径至少部分地大于插座的对应内部尺寸或至少一个内径，并且其中插入部分和插座适于产生径向作用 将第一和第二壳体部件相互夹紧在预定义组件构造中。
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公开(公告)号：US20120071836A1
公开(公告)日：2012-03-22
申请号：US13262921
申请日：2010-04-20
申请人： Axel Forstreuter , Michael Helmer , Claudia Matthias , Peter Nober , Reza Shahbazfar , Benjamin Schäfer , Leo Zeimetz , Uwe Dasbach
发明人： Axel Forstreuter , Michael Helmer , Claudia Matthias , Peter Nober , Reza Shahbazfar , Benjamin Schäfer , Leo Zeimetz , Uwe Dasbach
IPC分类号： A61M5/315
CPC分类号： A61M5/31515 , A61M5/24 , A61M5/3146 , A61M2005/2407 , A61M2207/00 , Y10T29/49826
摘要： The present invention relates to a drive mechanism for a drug delivery device as well as to a drug delivery device for dispensing of a dose of a medicinal product, wherein the drive mechanism comprises:a holder for a product-containing cartridge, the cartridge having a piston slidably arranged therein in an axial direction,a piston rod to be operably engaged with the cartridge's piston for dispensing of a dose of the medicinal product,at least one adjusting member slidably arranged in axial direction relative to the piston and/or relative to the piston rod for eliminating axial clearance between the piston and the piston rod,an interlock means adapted to interact with the adjusting member for mutually locking in position the piston and the piston rod irrespective of the relative distance between piston and piston rod.
摘要翻译： 本发明涉及一种用于药物输送装置的驱动机构以及用于分配药物产品剂量的药物输送装置，其中所述驱动机构包括：用于含产品的药筒的保持器，所述药筒具有 活塞，其沿轴向可滑动地布置在其中;活塞杆，其可与所述药筒的活塞可操作地接合，用于分配一定剂量的药用产品;至少一个调节构件，其相对于所述活塞在轴向方向上可滑动地布置，和/ 用于消除活塞和活塞杆之间的轴向间隙的活塞杆，适于与调节构件相互作用的互锁装置，用于相互锁定活塞和活塞杆的位置，而与活塞和活塞杆之间的相对距离无关。
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公开(公告)号：US20120330244A1
公开(公告)日：2012-12-27
申请号：US13500418
申请日：2010-10-08
申请人： Michael Helmer , Claudia Matthias , Leo Zeimetz , Reza Shahbazfar , Benjamin Schaefer , Carsten Mosebach
发明人： Michael Helmer , Claudia Matthias , Leo Zeimetz , Reza Shahbazfar , Benjamin Schaefer , Carsten Mosebach
IPC分类号： A61M5/315
CPC分类号： A61M5/24 , A61M5/3129 , A61M5/3146 , A61M5/31525 , A61M5/31533 , A61M2005/2407 , A61M2005/2488 , A61M2005/2492 , A61M2207/00
摘要： The present invention relates to a drug delivery device for dispensing of a predefined dose of a medicinal product, comprising: a housing, a cartridge holder adapted to receive a cartridge containing the medicinal product to be dispensed, the cartridge holder being connectable to the housing, a drive mechanism to be operably engaged with the cartridge for setting and/or dispensing of a predefined dose of the medicinal product, wherein the drive mechanism is axially slidingly supported in the housing for compensating axial clearance between the drive mechanism and the cartridge and wherein the drive mechanism is axially fixable relative to the housing.
摘要翻译： 本发明涉及一种用于分配预定剂量的药用产品的药物递送装置，包括：壳体，适于容纳包含要分配的药物的药筒的药筒保持器，药筒保持器可连接到外壳， 与药筒可操作地接合以用于设定和/或分配预定剂量的药物的驱动机构，其中所述驱动机构轴向滑动地支撑在所述壳体中，以补偿所述驱动机构和所述药筒之间的轴向间隙，并且其中 驱动机构相对于壳体可轴向固定。
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公开(公告)号：US08900203B2
公开(公告)日：2014-12-02
申请号：US13500418
申请日：2010-10-08
申请人： Michael Helmer , Claudia Matthias , Leo Zeimetz , Reza Shahbazfar , Benjamin Schaefer , Carsten Mosebach
发明人： Michael Helmer , Claudia Matthias , Leo Zeimetz , Reza Shahbazfar , Benjamin Schaefer , Carsten Mosebach
CPC分类号： A61M5/24 , A61M5/3129 , A61M5/3146 , A61M5/31525 , A61M5/31533 , A61M2005/2407 , A61M2005/2488 , A61M2005/2492 , A61M2207/00
摘要： The present invention relates to a drug delivery device for dispensing of a predefined dose of a medicinal product, comprising: a housing, a cartridge holder adapted to receive a cartridge containing the medicinal product to be dispensed, the cartridge holder being connectable to the housing, a drive mechanism to be operably engaged with the cartridge for setting and/or dispensing of a predefined dose of the medicinal product, wherein the drive mechanism is axially slidingly supported in the housing for compensating axial clearance between the drive mechanism and the cartridge and wherein the drive mechanism is axially fixable relative to the housing.
摘要翻译： 本发明涉及一种用于分配预定剂量的药用产品的药物递送装置，包括：壳体，适于容纳包含要分配的药物的药筒的药筒保持器，药筒保持器可连接到外壳， 与药筒可操作地接合以用于设定和/或分配预定剂量的药物的驱动机构，其中所述驱动机构轴向滑动地支撑在所述壳体中，以补偿所述驱动机构和所述药筒之间的轴向间隙，并且其中 驱动机构相对于壳体可轴向固定。
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公开(公告)号：US20150302778A1
公开(公告)日：2015-10-22
申请号：US13989881
申请日：2011-12-06
CPC分类号： G09B23/285 , A61M5/24 , A61M5/31505 , A61M5/31511 , A61M5/31513 , A61M2005/31508 , G09B23/28
摘要： The present invention relates to a cartridge for a drug delivery device comprising of a body of substantially cylindrical shape, a piston slidably disposed in the body along two opposite axial directions, along a distal and along a proximal direction, and at least one friction means operably engaged with the piston to generate a pre-defined friction force between the piston and an inside wall of the body, when the piston is displaced relative to the body, wherein in response to an axial displacement of the piston relative to the body in distal direction and in proximal direction, the at least one friction means is adapted to generate respective proximal and distal friction forces that are different in magnitude.
摘要翻译： 本发明涉及一种用于药物输送装置的药筒，其包括基本上圆柱形的主体，沿着远端和近端方向沿着两个相对的轴向方向可滑动地设置在主体内的活塞，以及可操作地至少一个摩擦装置 当活塞相对于主体移动时，活塞与活塞接合以在活塞和主体的内壁之间产生预定义的摩擦力，其中响应于活塞相对于主体在远端方向上的轴向位移 并且在近侧方向上，所述至少一个摩擦装置适于产生大小不同的相应的近端和远端摩擦力。
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公开(公告)号：US09336690B2
公开(公告)日：2016-05-10
申请号：US13989881
申请日：2011-12-06
CPC分类号： G09B23/285 , A61M5/24 , A61M5/31505 , A61M5/31511 , A61M5/31513 , A61M2005/31508 , G09B23/28
摘要： The present invention relates to a cartridge for a drug delivery device comprising of a body of substantially cylindrical shape, a piston slidably disposed in the body along two opposite axial directions, along a distal and along a proximal direction, and at least one friction means operably engaged with the piston to generate a pre-defined friction force between the piston and an inside wall of the body, when the piston is displaced relative to the body, wherein in response to an axial displacement of the piston relative to the body in distal direction and in proximal direction, the at least one friction means is adapted to generate respective proximal and distal friction forces that are different in magnitude.
摘要翻译： 本发明涉及一种用于药物输送装置的药筒，其包括基本上圆柱形的主体，沿着远端和近端方向沿着两个相对的轴向方向可滑动地设置在主体内的活塞，以及可操作地至少一个摩擦装置 当活塞相对于主体移动时，活塞与活塞接合以在活塞和主体的内壁之间产生预定义的摩擦力，其中响应于活塞相对于主体在远端方向上的轴向位移 并且在近侧方向上，所述至少一个摩擦装置适于产生大小不同的相应的近端和远端摩擦力。
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公开(公告)号：US08986259B2
公开(公告)日：2015-03-24
申请号：US12791499
申请日：2010-06-01
申请人： Michael Helmer , Christoph Eissengarthen , Winfried Huthmacher , Carsten Mosebach , Leo Zeimetz
发明人： Michael Helmer , Christoph Eissengarthen , Winfried Huthmacher , Carsten Mosebach , Leo Zeimetz
CPC分类号： A61M5/31515 , A61M5/24 , A61M5/3146 , A61M5/31511 , A61M5/31555 , A61M5/3156 , A61M5/3158 , A61M2005/2407 , A61M2005/3152 , A61M2207/00 , Y10T29/49826
摘要： Various embodiments of piston rod assemblies, drug delivery devices making use of such piston rod assemblies, and methods for assembling such piston rod assemblies and drug delivery devices are provided. In one embodiment, a piston rod assembly for a drug delivery device is provided, wherein the piston rod assembly is configured to engage a piston of a medicament cartridge. The piston rod assembly comprises (i) a piston rod, (ii) at least one adjusting member displaceably engaged with a distal end section of the piston rod, wherein the at least one adjusting member is displaceable along a long axis of the piston rod, and (iii) at least one interlock member configured to mutually lock the at least one adjusting member and the piston rod in an arbitrary relative axial position.
摘要翻译： 提供了使用这种活塞杆组件的活塞杆组件，药物输送装置的各种实施例，以及用于组装这种活塞杆组件和药物输送装置的方法。 在一个实施例中，提供了一种用于药物输送装置的活塞杆组件，其中活塞杆组件构造成与药剂盒的活塞接合。 活塞杆组件包括（i）活塞杆，（ii）可移动地与活塞杆的远端部分接合的至少一个调节构件，其中所述至少一个调节构件可沿着活塞杆的长轴线移动， 和（iii）至少一个互锁构件，构造成将至少一个调节构件和活塞杆相互锁定在任意的相对轴向位置。
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公开(公告)号：US20110245780A1
公开(公告)日：2011-10-06
申请号：US12791499
申请日：2010-06-01
申请人： Michael Helmer , Christoph Eissengarthen , Winfried Huthmacher , Carsten Mosebach , Leo Zeimetz
发明人： Michael Helmer , Christoph Eissengarthen , Winfried Huthmacher , Carsten Mosebach , Leo Zeimetz
CPC分类号： A61M5/31515 , A61M5/24 , A61M5/3146 , A61M5/31511 , A61M5/31555 , A61M5/3156 , A61M5/3158 , A61M2005/2407 , A61M2005/3152 , A61M2207/00 , Y10T29/49826
摘要： Various embodiments of piston rod assemblies, drug delivery devices making use of such piston rod assemblies, and methods for assembling such piston rod assemblies and drug delivery devices are provided. In one embodiment, a piston rod assembly for a drug delivery device is provided, wherein the piston rod assembly is configured to engage a piston of a medicament cartridge. The piston rod assembly comprises (i) a piston rod, (ii) at least one adjusting member displaceably engaged with a distal end section of the piston rod, wherein the at least one adjusting member is displaceable along a long axis of the piston rod, and (iii) at least one interlock member configured to mutually lock the at least one adjusting member and the piston rod in an arbitrary relative axial position.
摘要翻译： 提供了使用这种活塞杆组件的活塞杆组件，药物输送装置的各种实施例，以及用于组装这种活塞杆组件和药物输送装置的方法。 在一个实施例中，提供了一种用于药物输送装置的活塞杆组件，其中活塞杆组件构造成与药剂盒的活塞接合。 活塞杆组件包括（i）活塞杆，（ii）可移动地与活塞杆的远端部分接合的至少一个调节构件，其中所述至少一个调节构件可沿着活塞杆的长轴线移动， 和（iii）至少一个互锁构件，构造成将至少一个调节构件和活塞杆相互锁定在任意的相对轴向位置。
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