公开(公告)号：US20240350740A1

公开(公告)日：2024-10-24

申请号：US18760445

申请日：2024-07-01

申请人： NOVARTIS AG

发明人： Andrew BRYANT ,  Heinrich BUETTGEN ,  Wolfgang Papst ,  Marie Picci

IPC分类号： A61M5/315 ,  A61F9/00 ,  A61M5/00 ,  A61M5/28 ,  A61M5/31 ,  A61P27/02

CPC分类号： A61M5/31513 ,  A61M5/001 ,  A61M5/28 ,  A61M5/31505 ,  A61P27/02 ,  A61F9/0017 ,  A61M2005/3104 ,  A61M5/3137 ,  A61M2005/3139 ,  A61M2005/31508 ,  Y10T29/49826

摘要： The invention provides a syringe for use in an ophthalmic injection. The syringe comprises a body, a stopper and a plunger. The body comprises an outlet at an outlet end and the stopper is arranged within the body such that a front surface of the stopper and the body define a variable volume chamber from which a fluid can be expelled though the outlet. The plunger comprises a plunger contact surface at a first end and a rod extends between the plunger contact surface and a rear portion. The plunger contact surface is arranged to contact the stopper but not couple thereto, such that the plunger can be used to force the stopper towards the outlet end of the body, reducing the volume of the variable volume chamber, but not to move the stopper away from the outlet end.

公开(公告)号：US12115362B2

公开(公告)日：2024-10-15

申请号：US16404545

申请日：2019-05-06

申请人： NOBLE INTERNATIONAL, INC.

发明人： Jeff Baker ,  Francis Michael Siemer ,  Christopher Chung

IPC分类号： A61M5/32 ,  A61M5/315 ,  A61M5/50 ,  A61M5/20 ,  A61M5/46

CPC分类号： A61M5/3275 ,  A61M5/31501 ,  A61M5/3202 ,  A61M5/3213 ,  A61M5/322 ,  A61M5/3221 ,  A61M5/3232 ,  A61M5/3245 ,  A61M5/502 ,  A61M5/5086 ,  A61M2005/2086 ,  A61M2005/31508 ,  A61M2005/3151 ,  A61M5/31511 ,  A61M5/3204 ,  A61M2005/3247 ,  A61M5/326 ,  A61M5/46 ,  A61M2005/5033 ,  A61M2205/583 ,  A61M2205/59

摘要： A container for delivering a medicament to a target location includes a housing having a proximal end and a distal end, the housing including a cap locking tab at the distal end, and a vial containing the medicament. The container includes a plunger slidable within the vial from a proximal end to a distal end of the vial to dispel the medicament, an injection member associated with the distal end of the vial, such that the medicament dispelled from the vial passes through the injection member to the target location, and a slidable interaction member associated with the distal end of the vial configured to slide with the vial. An interaction between the slidable interaction member and the cap locking tab causes the cap locking tab to bias outward, and placement of a safety cap on the container after use locks the safety cap onto the container via an interaction with the cap locking tab. The container may further include a resistance feature to control movement of a plunger rod relative to the vial.

公开(公告)号：US20240216612A1

公开(公告)日：2024-07-04

申请号：US18558547

申请日：2022-05-11

申请人： Dali Medical Devices LTD.

发明人： David DAILY ,  Gad LEWKONYA ,  Lior RADAY ,  Hagay Drori ,  Dmitri SARKOROV ,  Guy Keenan ,  Ziv Cahani ,  Sasha Leikin ,  Amir Loval ,  Omri Bar Zeev

IPC分类号： A61M5/20 ,  A61M5/315

CPC分类号： A61M5/2066 ,  A61M5/31501 ,  A61M2005/31508

摘要： A dual chamber injection system, comprising a guiding element arranged along a longitudinal axis and configured to at least partially contain a medicament container, the guiding element defines an inner surface and at least one protrusion extending radially inwardly therefrom; a plunger rod assembly, comprising a plunger outer portion arranged along the longitudinal axis and a plunger inner portion arranged concentrically within the plunger outer portion and having at least one guiding groove arranged on an outer surface of the plunger inner portion; the plunger outer portion is disposed externally relative to the guiding element; the plunger inner portion is at least partially received into the guiding element; and wherein the plunger rod assembly is displaceable relative to the guiding element and the displacement is guided by engagement of the at least one protrusion with the at least one guiding groove.

公开(公告)号：US20240123153A1

公开(公告)日：2024-04-18

申请号：US18392932

申请日：2023-12-21

申请人： Allergan, Inc.

发明人： Bastien Mandaroux ,  Shushuo Wu ,  Lance Hussey

IPC分类号： A61M5/31 ,  A61M5/315

CPC分类号： A61M5/3137 ,  A61M5/31505 ,  A61M5/31511 ,  A61M5/31513 ,  A61B2017/00792 ,  A61M2005/31508

摘要： An aspiration and injection device is provided that can allow for ergonomic, safe, and precise aspiration of a target site and ejection of a medicament to the target site. The device can include a syringe barrel, a flange extender couplable to the barrel, and plunger that can be engaged by a hand and/or one or more finger of a user to perform aspiration and injection at a target site.

公开(公告)号：US20240108808A1

公开(公告)日：2024-04-04

申请号：US18540155

申请日：2023-12-14

申请人： Becton, Dickinson and Company

发明人： Paul P. Marici ,  Xiaoyu Sun ,  Jonathan Marek Zalot ,  Youstina Matta

IPC分类号： A61M5/315 ,  A61L2/07 ,  A61L2/08 ,  A61M5/31

CPC分类号： A61M5/31501 ,  A61L2/07 ,  A61L2/08 ,  A61M5/3129 ,  A61M5/31513 ,  A61M5/31563 ,  A61L2202/23 ,  A61M2005/3114 ,  A61M2005/3117 ,  A61M2005/31508 ,  A61M2207/10

摘要： Syringe assemblies are provided including a partially pre-filled syringe barrel and a plunger rod that incorporates one or more retention elements on the plunger rod that prevents solution from entering a non-sterile area of the syringe when the plunger rod is pulled back. Methods to manufacture a sterilized partially-filled pre-fill syringe assembly are also disclosed.

公开(公告)号：US11944795B2

公开(公告)日：2024-04-02

申请号：US17374003

申请日：2021-07-13

申请人： Owen Mumford Limited

发明人： Callum Davies ,  Abiodun Falodi ,  Matthew Farmer ,  Oliver Gould ,  Oliver Hyde ,  Parshia Moghadas ,  Timothy Muller ,  Tahir Shabudin

IPC分类号： A61M5/315 ,  A61M5/20 ,  A61M5/32 ,  A61M5/24

CPC分类号： A61M5/31513 ,  A61M5/2033 ,  A61M5/31511 ,  A61M5/3202 ,  A61M5/326 ,  A61M2005/2073 ,  A61M5/24 ,  A61M2005/31508 ,  A61M2005/31521 ,  A61M2207/00 ,  A61M2207/10

摘要： An injection device is disclosed comprising a plunger for expressing medicament from a syringe and a delivery mechanism arranged in use to provide a forward biasing force to urge the plunger from a first rearward position to a second forward position to express a dose from the syringe. A latch arrangement is provided that releasably holds the plunger against the force of the delivery mechanism. The latch arrangement comprising at least two resilient segments which define opposing sections of an aperture within which a rearward end of the plunger is retained in the rearward position. A trigger is provided for releasing the plunger in use, the trigger being arranged to outwardly deflect at least one of the resilient segments such that the aperture is expanded to release the rearward end of the plunger. A method of manufacturing the injection device is also enclosed.

公开(公告)号：US11890457B2

公开(公告)日：2024-02-06

申请号：US16798153

申请日：2020-02-21

申请人： Allergan, Inc.

发明人： Bastien Mandaroux ,  Shushuo Wu ,  Lance Hussey

IPC分类号： A61M5/31 ,  A61M5/178 ,  A61M5/315 ,  A61B17/00

CPC分类号： A61M5/3137 ,  A61M5/31505 ,  A61M5/31511 ,  A61M5/31513 ,  A61B2017/00792 ,  A61M5/1782 ,  A61M2005/3139 ,  A61M2005/31508 ,  A61M2205/586 ,  A61M2207/00

摘要： An aspiration and injection device is provided that can allow for ergonomic, safe, and precise aspiration of a target site and ejection of a medicament to the target site. The device can include a syringe barrel, a flange extender couplable to the barrel, and plunger that can be engaged by a hand and/or one or more finger of a user to perform aspiration and injection at a target site.

公开(公告)号：US20230347063A1

公开(公告)日：2023-11-02

申请号：US18307417

申请日：2023-04-26

申请人： SCHOTT Pharma Schweiz AG

发明人： Raymond Moser

IPC分类号： A61M5/315

CPC分类号： A61M5/31501 ,  A61M2005/3151 ,  A61M2005/31508 ,  A61M2205/0216

摘要： A syringe includes: a container body including an inner wall; a plunger including a plunger rod, the plunger rod being disposed at least partially within the container body; and a locking arrangement configured for locking a position of the plunger rod relative to the container body and for being operable between at least a locked position and an unlocked position, the locking arrangement including at least one deformable element which is configured for applying a locking force between the plunger rod and the inner wall of the container body when the locking arrangement is in the locked position and for releasing the locking force between the plunger rod and the inner wall of the container body when the locking arrangement is changed from the locked position to the unlocked position.

公开(公告)号：US20230201468A1

公开(公告)日：2023-06-29

申请号：US18116473

申请日：2023-03-02

申请人： Genentech, Inc.

发明人： Lionel Vedrine ,  Steven N. Roe ,  Mukund Patel

IPC分类号： A61M5/315 ,  A61M5/24 ,  A61F9/00 ,  A61M5/31 ,  A61M5/32 ,  A61M5/36

CPC分类号： A61M5/31513 ,  A61M5/31586 ,  A61M5/31573 ,  A61M5/24 ,  A61M5/3157 ,  A61F9/0017 ,  A61M5/2448 ,  A61M5/2459 ,  A61M5/3137 ,  A61M5/3145 ,  A61M5/3146 ,  A61M5/31505 ,  A61M5/31528 ,  A61M5/31581 ,  A61M5/31596 ,  A61M5/3202 ,  A61M5/3298 ,  A61M5/36 ,  A61M2005/31508 ,  A61M5/284

摘要： Apparatus and methods for medicament delivery. The apparatus may include, and the methods may involve, a delivery device for delivering a target amount of the medicament from a distal end of the device. The device may include a rod for moving a plunger that discharges the medicament from the distal end. The device may avoid or reduce deformation of the plunger during the discharge. The plunger motion may be stopped by detent that interacts with the rod. The apparatus and the methods may provide an operator indication of progress of stages of operation. The device may feature triggers corresponding to stages of medicament displacement from the device, such as pre-delivery stages, including priming.

公开(公告)号：US20230158245A1

公开(公告)日：2023-05-25

申请号：US17801662

申请日：2021-02-10

申请人： Obrist Closures Switzerland GmbH

发明人： Frederic Chave ,  Philippe Bardet

IPC分类号： A61M5/315

CPC分类号： A61M5/31505 ,  A61M2005/31508 ,  A61M2005/3151

摘要： A syringe is provided and comprising a barrel having an outlet and a piston movable along the inside of the barrel to take in or expel fluid from the outlet. The syringe comprises brake means for influencing movement of the piston.