摘要:
This invention relates to certain novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl cytidine, uridine and guanosine derivatives, and compositions thereof, which are useful in the treatment of patients afflicted with neoplastic or viral disease states.
摘要:
This invention relates to certain novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl cytidine, uridine and guanosine derivatives, and compositions thereof, which are useful in the treatment of patients afflicted with neoplastic or viral disease states.
摘要:
This invention relates to certain novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl cytidine, uridine and guanosine derivatives, and compositions thereof, which are useful in the treatment of patients afflicted with neoplastic or viral disease states.
摘要:
This invention relates to certain novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl cytidine, uridine and guanosine derivatives, and compositions thereof, which are useful in the treatment of patients afflicted with neoplastic or viral disease states.
摘要:
This invention relates to certain novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl cytidine, uridine and guanosine derivatives, and compositions thereof, which are useful in the treatment of patients afflicted with neoplastic or viral disease states.
摘要:
This invention relates to certain novel di- and tetra-fluoro analogs of squalene and to their methods of use in lowering plasma cholesterol and in inhibiting squalene epoxidase in patients in need thereof.
摘要:
This invention relates to certain acetylenic, cyano and allenic aristeromycin/adenosine derivatives which are useful in inhibiting AdoMet-dependent transmethylation and in the treatment of patients afflicted with neoplastic or viral disease states.
摘要:
This invention relates to certain novel di- and tetra-fluoro analogs of squalene and to their methods of use in lowering plasma cholesterol and in inhibiting squalene epoxidase in patients in need thereof.
摘要:
Systems, methods, non-transitory computer-readable media storing computer program instructions for causing a computer device to implement methods, and the like utilize weather information from one or a variety of locations to estimate costs for providing weather-dependent work, and to provide financial controls for weather-dependent work allegedly performed. One method includes utilizing historical weather information relating to performance of weather-dependent work at a work location to generate an estimate of an anticipated frequency with which weather-dependent work will be necessary, utilizing information to estimate an anticipated cost per incident for performing weather-dependent work at the selected work location, and using such information at a plurality of locations to generate an aggregate bid for performing weather-dependent work at the locations. Weather information is also used to audit weather-dependent work allegedly performed at the work locations to provide financial controls to the aggregated weather-dependent work in compliance with law and regulation.