公开(公告)号：US06692324B2

公开(公告)日：2004-02-17

申请号：US09810531

申请日：2001-03-15

申请人： Michael L. Simpson ,  Douglas H. Lowndes ,  Vladimir I. Merkulov ,  Michael A. Guillorn ,  Charles L. Britton

发明人： Michael L. Simpson ,  Douglas H. Lowndes ,  Vladimir I. Merkulov ,  Michael A. Guillorn ,  Charles L. Britton

IPC分类号： H01J902

CPC分类号： B82Y10/00 ,  H01J3/022 ,  H01J9/025 ,  H01J2201/30469 ,  Y10S977/843 ,  Y10S977/847 ,  Y10S977/891

摘要： Systems and methods are described for a single self-aligned carbon nanofiber emitters within a dielectric well. A method, includes: providing a substrate; defining lithographically a catalyst particle, the catalyst particle coupled to the substrate; depositing a dielectric layer, the dielectric layer coupled to the substrate; depositing an extractor layer, the extractor layer coupled to the dielectric layer; forming an extractor aperture in the extractor layer; forming a dielectric well in the dielectric layer to uncover the catalyst particle; and then fabricating at a location of the catalyst particle and within the dielectric well a single self-aligned carbon containing tip i) having a base located substantially at the bottom of the dielectric well and ii) extending substantially away from the substrate using plasma enhanced chemical vapor deposition.

摘要翻译： 描述了电介质井内单个自对准碳纳米纤维发射体的系统和方法。 一种方法，包括：提供基底; 以平版印刷催化剂颗粒，所述催化剂颗粒耦合到所述基材; 沉积介电层，所述电介质层耦合到所述衬底; 沉积提取器层，所述提取器层耦合到所述电介质层; 在提取器层中形成提取器孔; 在介电层中形成电介质阱以露出催化剂颗粒; 然后在催化剂颗粒的位置和电介质阱内制造单个自对准含碳尖端i），其具有基本位于电介质阱底部的基部，以及ii）使用等离子体增强化学品基本上远离衬底延伸 气相沉积。

公开(公告)号：US07825819B2

公开(公告)日：2010-11-02

申请号：US12268657

申请日：2008-11-11

申请人： Govindarajan Muralidharan ,  Charles L. Britton ,  James Pearce ,  Usha Jagadish ,  Vinod K. Sikka

发明人： Govindarajan Muralidharan ,  Charles L. Britton ,  James Pearce ,  Usha Jagadish ,  Vinod K. Sikka

IPC分类号： G08B21/00

CPC分类号： G08B13/1663 ,  G08B31/00

摘要： A low-power shock sensing system includes at least one shock sensor physically coupled to a chemical storage tank to be monitored for impacts, and an RF transmitter which is in a low-power idle state in the absence of a triggering signal. The system includes interface circuitry including or activated by the shock sensor, wherein an output of the interface circuitry is coupled to an input of the RF transmitter. The interface circuitry triggers the RF transmitter with the triggering signal to transmit an alarm message to at least one remote location when the sensor senses a shock greater than a predetermined threshold. In one embodiment the shock sensor is a shock switch which provides an open and a closed state, the open state being a low power idle state.

摘要翻译： 低功率冲击感测系统包括至少一个物理耦合到要监控冲击的化学品储罐的冲击传感器，以及在没有触发信号的情况下处于低功率空闲状态的RF发射器。 该系统包括由冲击传感器包括或激活的接口电路，其中接口电路的输出耦合到RF发射器的输入端。 当传感器感测到大于预定阈值的冲击时，接口电路触发具有触发信号的RF发射器，以向至少一个远程位置发送警报消息。 在一个实施例中，冲击传感器是提供打开和关闭状态的冲击开关，打开状态是低功率空闲状态。

公开(公告)号：US20090240271A1

公开(公告)日：2009-09-24

申请号：US12052992

申请日：2008-03-21

申请人： Charles L. Britton ,  Brian R. D'Urso ,  Edward Chaum ,  John T. Simpson ,  Justin S. Baba ,  M. Nance Ericson ,  Robert J. Warmack

发明人： Charles L. Britton ,  Brian R. D'Urso ,  Edward Chaum ,  John T. Simpson ,  Justin S. Baba ,  M. Nance Ericson ,  Robert J. Warmack

IPC分类号： A61F9/00

CPC分类号： A61F9/00736 ,  A61B17/205 ,  A61F9/007 ,  A61F9/00727

摘要： In one embodiment, the present invention provides a method of removing scar tissue from an eye that includes inserting a device including an array of micro-rods into an eye, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature; contacting a scar tissue with the array of micro-rods; and removing the array of micro-rods and the scar tissue from the eye. In another embodiment, the present invention provides a medical device for engaging a tissue including and an array of glass micro-rods, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature opposite a base of the array of glass micro-rods that is connected to the cannula, wherein the sharp feature of the at least one micro-rod is angled from a plane that is normal to a face of the base of the array of glass micro-rods.

摘要翻译： 在一个实施方案中，本发明提供了一种从眼睛去除疤痕组织的方法，包括将包括微棒阵列的装置插入到眼睛中，其中玻璃微棒阵列的至少一个玻璃微棒包括 一个尖锐的特征; 使疤痕组织与微杆阵列接触; 并从眼睛中移除微杆阵列和瘢痕组织。 在另一个实施方案中，本发明提供了一种用于接合包括玻璃微棒和玻璃微棒的阵列的组织的医疗装置，其中所述玻璃微棒阵列的至少一个玻璃微棒包括与所述玻璃微棒的基底相对的尖锐特征 连接到插管的玻璃微杆的阵列，其中所述至少一个微杆的尖锐特征从与所述玻璃微棒阵列的基部的面垂直的平面成角度。

公开(公告)号：US5590104A

公开(公告)日：1996-12-31

申请号：US316193

申请日：1994-09-30

申请人： Charles L. Britton

发明人： Charles L. Britton

IPC分类号： G11C27/00

CPC分类号： G11C27/00

摘要： A method and apparatus for correcting common-mode noise and pedestal noise in a multichannel array of switched-capacitor analog memories wherein each analog memory is connected to an associated analog-to-digital converter. The apparatus comprises a single differential element in two different embodiments. In a first embodiment, the differential element is a reference analog memory connected to a buffer. In the second embodiment, the differential element is a reference analog memory connected to a reference analog-to-digital connected to an array of digital summing circuits.

摘要翻译： 一种用于校正开关电容器模拟存储器的多通道阵列中的共模噪声和基座噪声的方法和装置，其中每个模拟存储器连接到相关联的模拟 - 数字转换器。 该装置包括两个不同实施例中的单个差分元件。 在第一实施例中，差分元件是连接到缓冲器的参考模拟存储器。 在第二实施例中，差分元件是连接到与数字求和电路阵列连接的参考模拟数字量的参考模拟存储器。

公开(公告)号：US08425596B2

公开(公告)日：2013-04-23

申请号：US12052992

申请日：2008-03-21

申请人： Charles L. Britton ,  Brian R. D'Urso ,  Edward Chaum ,  John T. Simpson ,  Justin S. Baba ,  M. Nance Ericson ,  Robert J. Warmack

发明人： Charles L. Britton ,  Brian R. D'Urso ,  Edward Chaum ,  John T. Simpson ,  Justin S. Baba ,  M. Nance Ericson ,  Robert J. Warmack

IPC分类号： A61F2/16

CPC分类号： A61F9/00736 ,  A61B17/205 ,  A61F9/007 ,  A61F9/00727

摘要： In one embodiment, the present invention provides a method of removing scar tissue from an eye that includes inserting a device including an array of micro-rods into an eye, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature; contacting a scar tissue with the array of micro-rods; and removing the array of micro-rods and the scar tissue from the eye. In another embodiment, the present invention provides a medical device for engaging a tissue including and an array of glass micro-rods, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature opposite a base of the array of glass micro-rods that is connected to the cannula, wherein the sharp feature of the at least one micro-rod is angled from a plane that is normal to a face of the base of the array of glass micro-rods.

摘要翻译： 在一个实施方案中，本发明提供了一种从眼睛去除疤痕组织的方法，包括将包括微棒阵列的装置插入到眼睛中，其中玻璃微棒阵列的至少一个玻璃微棒包括 一个尖锐的特征; 使疤痕组织与微杆阵列接触; 并从眼睛中移除微杆阵列和瘢痕组织。 在另一个实施方案中，本发明提供了一种用于接合包括玻璃微棒和玻璃微棒的阵列的组织的医疗装置，其中所述玻璃微棒阵列的至少一个玻璃微棒包括与所述玻璃微棒的基底相对的尖锐特征 连接到插管的玻璃微杆的阵列，其中所述至少一个微杆的尖锐特征从与所述玻璃微棒阵列的基部的面垂直的平面成角度。

公开(公告)号：US20090072964A1

公开(公告)日：2009-03-19

申请号：US12268657

申请日：2008-11-11

申请人： GOVINDARAJAN MURALIDHARAN ,  Charles L. Britton ,  James W. Pearce ,  Usha Jagadish ,  Vinod K. Sikka

发明人： GOVINDARAJAN MURALIDHARAN ,  Charles L. Britton ,  James W. Pearce ,  Usha Jagadish ,  Vinod K. Sikka

IPC分类号： G08B1/08

CPC分类号： G08B13/1663 ,  G08B31/00

摘要： A low-power shock sensing system includes at least one shock sensor physically coupled to a chemical storage tank to be monitored for impacts, and an RF transmitter which is in a low-power idle state in the absence of a triggering signal. The system includes interface circuitry including or activated by the shock sensor, wherein an output of the interface circuitry is coupled to an input of the RF transmitter. The interface circuitry triggers the RF transmitter with the triggering signal to transmit an alarm message to at least one remote location when the sensor senses a shock greater than a predetermined threshold. In one embodiment the shock sensor is a shock switch which provides an open and a closed state, the open state being a low power idle state.

摘要翻译： 低功率冲击感测系统包括至少一个物理耦合到要监控冲击的化学品储罐的冲击传感器，以及在没有触发信号的情况下处于低功率空闲状态的RF发射器。 该系统包括由冲击传感器包括或激活的接口电路，其中接口电路的输出耦合到RF发射器的输入端。 当传感器感测到大于预定阈值的冲击时，接口电路触发具有触发信号的RF发射器，以向至少一个远程位置发送警报消息。 在一个实施例中，冲击传感器是提供打开和关闭状态的冲击开关，打开状态是低功率空闲状态。

公开(公告)号：US5671172A

公开(公告)日：1997-09-23

申请号：US738626

申请日：1996-10-29

申请人： Charles L. Britton

发明人： Charles L. Britton

IPC分类号： G11C27/00

CPC分类号： G11C27/00

摘要： A method and apparatus for correcting common-mode noise and pedestal noise in a multichannel array of switched-capacitor analog memories wherein each analog memory is connected to an associated analog-to-digital converter. The apparatus comprises a single differential element in two different embodiments. In a first embodiment, the differential element is a reference analog memory connected to a buffer. In the second embodiment, the differential dement is a reference analog memory connected to a reference analog-to-digital connected to an array of digital summing circuits.

摘要翻译： 一种用于校正开关电容器模拟存储器的多通道阵列中的共模噪声和基座噪声的方法和装置，其中每个模拟存储器连接到相关联的模拟 - 数字转换器。 该装置包括两个不同实施例中的单个差分元件。 在第一实施例中，差分元件是连接到缓冲器的参考模拟存储器。 在第二实施例中，差分纹理是连接到与数字求和电路阵列连接的参考模数与数字的参考模拟存储器。

公开(公告)号：US08591481B2

公开(公告)日：2013-11-26

申请号：US12052971

申请日：2008-03-21

申请人： Charles L. Britton ,  Brian R. D'Urso ,  Edward Chaum ,  John T. Simpson ,  Justin S. Baba ,  M. Nance Ericson ,  Robert J. Warmack

发明人： Charles L. Britton ,  Brian R. D'Urso ,  Edward Chaum ,  John T. Simpson ,  Justin S. Baba ,  M. Nance Ericson ,  Robert J. Warmack

IPC分类号： A61M5/158

CPC分类号： A61F9/007 ,  A61B2017/320004 ,  A61F9/0017

摘要： In one embodiment, the present invention provides a device and method for treating recurrent corneal erosion. In one embodiment, the method includes the steps of contacting an epithelium layer of a cornea with an array of glass micro-rods including a plurality of sharp features having a length that penetrates a Bowman's layer of the eye, wherein the plurality of sharp features of the array of glass micro-rods produces a plurality of punctures in the Bowman's layer of the eye that are of micro-scale or less. In another embodiment, the present invention provides a method and device for drug delivery. In one embodiment, the device includes an array of glass micro-rods, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature opposite a base of the array of glass micro-rods, wherein the sharp feature includes a treated surface for delivering a chemical compound to the eye.

摘要翻译： 在一个实施方案中，本发明提供了用于治疗复发性角膜侵蚀的装置和方法。 在一个实施例中，该方法包括以下步骤：使角膜的上皮层与玻璃微杆阵列接触，所述玻璃微杆包括具有穿透眼睛Bowman层的长度的多个尖锐特征，其中多个尖锐特征 玻璃微棒的阵列在眼睛的Bowman层中产生微量级或更小的多个穿刺。 在另一个实施方案中，本发明提供用于药物递送的方法和装置。 在一个实施例中，该装置包括玻璃微棒阵列，其中玻璃微棒阵列的至少一个玻璃微棒包括与玻璃微棒阵列相对的尖锐特征，其中尖锐 特征包括用于将化学化合物递送至眼睛的处理表面。

公开(公告)号：US20090240217A1

公开(公告)日：2009-09-24

申请号：US12052971

申请日：2008-03-21

申请人： Charles L. Britton ,  Brian R. D'Urso ,  Edward Chaum ,  John T. Simpson ,  Justin S. Baba ,  M. Nance Ericson ,  Robert J. Warmack

发明人： Charles L. Britton ,  Brian R. D'Urso ,  Edward Chaum ,  John T. Simpson ,  Justin S. Baba ,  M. Nance Ericson ,  Robert J. Warmack

IPC分类号： A61F9/00

CPC分类号： A61F9/007 ,  A61B2017/320004 ,  A61F9/0017

摘要： In one embodiment, the present invention provides a device and method for treating recurrent corneal erosion. In one embodiment, the method includes the steps of contacting an epithelium layer of a cornea with an array of glass micro-rods including a plurality of sharp features having a length that penetrates a Bowman's layer of the eye, wherein the plurality of sharp features of the array of glass micro-rods produces a plurality of punctures in the Bowman's layer of the eye that are of micro-scale or less. In another embodiment, the present invention provides a method and device for drug delivery. In one embodiment, the device includes an array of glass micro-rods, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature opposite a base of the array of glass micro-rods, wherein the sharp feature includes a treated surface for delivering a chemical compound to the eye.

摘要翻译： 在一个实施方案中，本发明提供了用于治疗复发性角膜侵蚀的装置和方法。 在一个实施例中，该方法包括以下步骤：使角膜的上皮层与玻璃微杆阵列接触，所述玻璃微杆包括具有穿透眼睛的Bowman层的长度的多个尖锐特征，其中多个尖锐特征 玻璃微棒的阵列在眼睛的Bowman层中产生微量级或更小的多个穿刺。 在另一个实施方案中，本发明提供用于药物递送的方法和装置。 在一个实施例中，该装置包括玻璃微棒阵列，其中玻璃微棒阵列的至少一个玻璃微棒包括与玻璃微棒阵列相对的尖锐特征，其中尖锐 特征包括用于将化学化合物递送至眼睛的处理表面。

公开(公告)号：US07450023B2

公开(公告)日：2008-11-11

申请号：US11346867

申请日：2006-02-03

申请人： Govindarajan Muralidharan ,  Charles L. Britton ,  James Pearce ,  Usha Jagadish ,  Vinod K. Sikka

发明人： Govindarajan Muralidharan ,  Charles L. Britton ,  James Pearce ,  Usha Jagadish ,  Vinod K. Sikka

IPC分类号： G08B21/00

CPC分类号： G08B13/1663 ,  G08B31/00

摘要： A low-power shock sensing system includes at least one shock sensor physically coupled to a chemical storage tank to be monitored for impacts, and an RF transmitter which is in a low-power idle state in the absence of a triggering signal. The system includes interference circuitry including or activated by the shock sensor, wherein an output of the interface circuitry is coupled to an input of the RF transmitter. The interface circuitry triggers the RF transmitting with the triggering signal to transmit an alarm message to at least one remote location when the sensor senses a shock greater than a predetermined threshold. In one embodiment the shock sensor is a shock switch which provides an open and a closed state, the open state being a low power idle state.

摘要翻译： 低功率冲击感测系统包括至少一个物理耦合到要监控冲击的化学品储罐的冲击传感器，以及在没有触发信号的情况下处于低功率空闲状态的RF发射器。 该系统包括干扰电路，包括由冲击传感器激活的干扰电路，其中接口电路的输出耦合到RF发射器的输入端。 当传感器感测到大于预定阈值的冲击时，接口电路触发具有触发信号的RF发射，以将报警消息发送到至少一个远程位置。 在一个实施例中，冲击传感器是提供打开和关闭状态的冲击开关，打开状态是低功率空闲状态。