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公开(公告)号：US06591472B1
公开(公告)日：2003-07-15
申请号：US09207644
申请日：1998-12-08
IPC分类号： B23P1700
CPC分类号： A61M25/0045 , A61M25/0009 , A61M25/0012 , A61M25/0015 , B29L2031/7542 , Y10T29/49798 , Y10T29/49982
摘要： Methods of fabricating medical vascular catheters adapted to be inserted into a blood vessel from an incision through the skin of a patient for introducing other devices or fluids for diagnostic or therapeutic purposes and particularly methods for fabricating such catheters with catheter bodies having catheter sections of differing flexibility are disclosed. Such catheter bodies having a proximal catheter body end and a distal catheter body end and formed of a proximal section and at least one distal section that have differing flexibilities are formed in a process comprising the steps of: (1) forming a continuous tubular inner jacket preferably of an inner liner and a reinforcement layer; (2) forming initial layer segments having an initial layer thickness along the length of the inner jacket from a material of first durometer hardness, whereby each initial layer segment is separated by a separation distance: (3) forming a final layer of a material of second durometer hardness with a second layer thickness over the tubular inner jacket along the separation distances and over and/or against the proximal and distal initial layer ends of the initial layer segments to form a continuous catheter body tubing; (4) severing the continuous catheter body tubing into catheter body lengths including a proximal catheter section formed of the material of second hardness and a distal catheter section of the material of first hardness; and (5) completing the catheter fabrication at the proximal catheter body end and the distal catheter body end. Centerless grinding of the catheter body or body tubing, formation of Intermediate catheter body sections, distal soft tips, and discontinuities in the reinforcement layer formed prior to step (2) are also disclosed.
摘要翻译： 制造医用血管导管的方法，其适于从切口穿过患者皮肤插入血管，用于引入其他装置或流体用于诊断或治疗目的，特别是制造具有导管体的方法，导管体具有不同柔性的导管部分 被披露。 具有近端导管主体端部和远侧导管主体端部并且由近端部分和至少一个具有不同柔性的远端部分形成的这种导管体形成在包括以下步骤的过程中：（1）形成连续的管状内护套 优选内衬和加强层; （2）从第一硬度硬度的材料形成具有沿着内护套长度的初始层厚度的初始层段，由此每个初始层段被隔开间隔距离：（3）形成最终层的材料的最终层 沿着分隔距离在管状内套上方具有第二层厚度的第二硬度计硬度，并且在初始层段的上和/或靠近初始和最初的初始层端部以形成连续的导管体管; （4）将连续导管体管切断成导管主体长度，包括由第二硬度的材料形成的近端导管部分和第一硬度材料的远侧导管部分; 和（5）在近端导管主体端和远侧导管主体端完成导管制造。 还公开了导管主体或体管的无心磨削，中间导管主体部分的形成，远端软尖端和在步骤（2）之前形成的加强层中的不连续性）。
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公开(公告)号：US06716231B1
公开(公告)日：2004-04-06
申请号：US09578244
申请日：2000-05-24
申请人： Nasser Rafiee , Jerry R. Brightbill , David S. Brin , Timothy P. Collins , Steven R. Dapolito , Barbara S. DeVaux , Nareak Douk , Albert H. Dunfee , Heng Mao , Michael S. Noone , Dennis L. Brooks , Robert D. Lashinski
发明人： Nasser Rafiee , Jerry R. Brightbill , David S. Brin , Timothy P. Collins , Steven R. Dapolito , Barbara S. DeVaux , Nareak Douk , Albert H. Dunfee , Heng Mao , Michael S. Noone , Dennis L. Brooks , Robert D. Lashinski
IPC分类号： A61M2900
CPC分类号： A61F2/013 , A61F2/01 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/008
摘要： The present invention is a distal protection device for use during a vascular treatment, such as angioplasty or atherectomy. A filter assembly located on the distal end of a delivery member is deployed distally of the vascular region to be treated to capture emboli released during and immediately after the procedure. The filter is then retracted to retain any captured emboli and then removed from the patient.
摘要翻译： 本发明是一种用于血管成形术或粥样斑块切除术的血管治疗期间的远端保护装置。 位于递送构件的远端上的过滤器组件被展开在待治疗的血管区域的远端以捕获在手术期间和之后立即释放的栓塞。 然后将过滤器缩回以保留任何捕获的栓塞，然后从患者中取出。
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公开(公告)号：US06210396B1
公开(公告)日：2001-04-03
申请号：US09339499
申请日：1999-06-24
IPC分类号： A61M25098
CPC分类号： A61M25/0108 , A61L29/18 , A61L31/18 , A61M25/0009
摘要： The present invention comprises a tubular catheter shaft defining at least one catheter shaft lumen and a radiopaque band made of a polymeric material loaded with a radiopaque material of greater than 40% by weight, suitable for visualization under fluoroscopy in catheters in the range of 3 French to 5 French. The distal soft tip is formed of a relatively flexible polymeric material, loaded with radiopaque material which is less radiopaque than the radiopaque band. The radiopaque band's proximal end adjoins the distal end of the catheter shaft. The radiopaque band's distal end adjoins the proximal end of the distal tip to form an attachment junction. A tubular sleeve fits coaxially over the radiopaque band, the distal end of the catheter shaft and the proximal end of the distal soft tip. The tubular sleeve adheres the catheter shaft distal end to the proximal end of the radiopaque band and adheres the soft tip proximal end to the distal end of the radiopaque band thereby aligning the soft tip lumen, the radiopaque band lumen, and the catheter shaft lumen. The proximal end of the tubular sleeve is bonded to a distal portion of the catheter shaft. The distal end of the tubular sheath is bonded to the proximal end of the soft distal tip. The radiopaque band is bonded to the tubular sheath thereby bridging the attachment junction. The tubular sleeve is made of a polymeric material loaded with a radiopaque material which is less radiopaque than the radiopaque band. The tubular sleeve is melt compatible with the radiopaque band, the catheter shaft distal end and the distal soft tip such that the tubular sleeve, the distal end of the catheter shaft, the radiopaque band and the proximal end of the distal soft tip bond.
摘要翻译： 本发明包括管状导管轴，其限定至少一个导管轴腔和由装载有大于40重量％的不透射线材料的聚合物材料制成的不透射带，适合于在3个法国的导管内的荧光透视下的可视化 到5法语。 远端软尖端由相对柔性的聚合物材料形成，该聚合材料装载不透射线不透射线的不透射线材料。 不透射线带的近端邻接导管轴的远端。 不透射线带的远端与远端尖端的近端相邻以形成附着结。 管状套筒同轴地配合在不透射线的带，导管轴的远端和远端软尖端的近端。 管状套管将导管轴远端粘附到不透射线带的近端，并将软尖端近端粘附到不透射线带的远端，从而对准软尖端腔，不透射线带腔和导管轴腔。 管状套管的近端结合到导管轴的远端部分。 管状护套的远端结合到软远侧末端的近端。 不透射线的带结合到管状护套，从而桥接连接结。 管状套筒由装载有不透射线不透射线的不透射线材料的聚合材料制成。 管状套筒与不透射线带，导管轴远端和远端软尖端熔融相容，使得管状套管，导管轴的远端，不透射线带和远端软尖端的近端结合。
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公开(公告)号：US5596996A
公开(公告)日：1997-01-28
申请号：US413524
申请日：1995-03-30
申请人： Mark A. Johanson , Michael S. Noone
发明人： Mark A. Johanson , Michael S. Noone
CPC分类号： A61M25/09 , A61M2025/09083
摘要： A catheter guidewire having an elongate core wire, an elongate tube defining a tube lumen, the proximal end of the tube being affixed to the distal end of the core wire. The tube has a smooth exterior surface and one or more plug segments filling the tube lumen, each plug segment having a stiffness less than that of the core wire and less than that of the proximally preceding plug segment. The proximal end of the proximal most plug segment is affixed to the distal end of the core wire, the distal end of the tube is affixed to the distal most plug segment. A smoothly rounded distal tip extends beyond and is affixed to the distal end of the tube. The tube may be formed of a super-elastic metallic member or formed from a synthetic resin. The tube wall thickness is preferably between 0.002 inches and 0.005 inches.
摘要翻译： 具有细长芯线的导管导丝，限定管腔的细长管，所述管的近端固定到芯线的远端。 管具有光滑的外表面和一个或多个填充管内腔的插塞段，每个插塞段的刚度小于芯线的刚度，并且小于近端前端插塞段的刚度。 最近的插塞段的近端固定到芯线的远端，管的远端固定在最远端插塞段上。 平滑的圆形远端尖端延伸超过并固定到管的远端。 管可以由超弹性金属构件形成或由合成树脂形成。 管壁厚度优选为0.002英寸至0.005英寸。
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公开(公告)号：US07909810B2
公开(公告)日：2011-03-22
申请号：US12325547
申请日：2008-12-01
申请人： Michael S. Noone
发明人： Michael S. Noone
CPC分类号： A61M25/10 , A61M2025/0681 , A61M2025/1052
摘要： A guiding catheter for providing proximal occlusion while intubating a branch vessel lumen in a patient. The catheter comprises an elongate hollow shaft having open proximal and distal ends and a resiliently compressible occluder fixed about the shaft adjacent the distal end, the occluder having a relaxed shape that tapers distally from a major diameter greater than a diameter of the vessel lumen. The occluder may comprise elastic foam material or an impermeable flexible cover clingingly enclosing a resilient support member.
摘要翻译： 用于在插管患者中的分支血管腔时提供近端闭塞的引导导管。 导管包括具有开放的近端和远端的细长空心轴和邻近远端固定在轴上的可弹性压缩的闭塞器，所述闭塞器具有从大于血管腔直径的大直径向远端渐缩的松弛形状。 封堵器可以包括弹性泡沫材料或密封地包围弹性支撑构件的不可渗透的柔性盖。
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6.发明授权Angiography luer hub having wings proximal to the plurality of grips and strain relief 失效血管造影术鲁尔枢纽具有靠近多个手柄和应变消除的翅膀公开(公告)号：US06228073B1
公开(公告)日：2001-05-08
申请号：US09211821
申请日：1998-12-15
申请人： Michael S. Noone , Cheryl Fay-Lauria , Bruce Adams
发明人： Michael S. Noone , Cheryl Fay-Lauria , Bruce Adams
IPC分类号： A61M2500
CPC分类号： A61M25/0014 , A61M5/007 , A61M25/0612 , A61M2025/0098 , Y10S128/912 , Y10S604/905
摘要： A hub for connecting a medical catheter in fluid communication with a medical device, such as a syringe, includes a tubular shaped body member which has an outer surface that is formed with a plurality of grips. The hub also has a pair or diametrically opposed wings which extend from the outer surface of the body member and it has a proximal end which is formed as a female luer fitting for engagement with the medical device. The distal end of the hub is formed with a spiral strain relief element having a passageway which receives the proximal end of the medical catheter. In operation, the spiral relief element supports the medical catheter and prevents kinking of the catheter near the hub during flexure of the catheter by providing for a progressive transition from the relative rigidity of the hub to the flexure required by the catheter.
摘要翻译： 用于连接与诸如注射器的医疗装置流体连通的医疗导管的轮毂包括具有形成有多个把手的外表面的管状本体构件。 毂还具有从主体构件的外表面延伸的一对或径向相对的翼，并且其具有形成为用于与医疗装置接合的阴路厄配件的近端。 轮毂的远端形成有螺旋应变消除元件，其具有容纳医用导管的近端的通道。 在操作中，螺旋形释放元件支撑医疗导管并且通过提供从轮毂的相对刚性到导管所需的挠曲的逐渐过渡来防止导管在导管弯曲期间靠近轮毂的扭结。
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公开(公告)号：US07354445B2
公开(公告)日：2008-04-08
申请号：US10736411
申请日：2003-12-15
IPC分类号： A61M29/00
CPC分类号： A61B17/221 , A61B2017/22042 , A61B2017/22049 , A61B2017/2212 , A61F2002/011
摘要： A system for treating a vascular condition, including a hollow guidewire, a core wire inserted through the hollow guidewire, and an embolic containment device. The core wire includes a tapered undulating section carried within the hollow guidewire. The embolic containment device is coupled between a distal end of the hollow guidewire and a distal end of the core wire. The tapered undulating section of the core wire provides frictional control of the embolic containment device based on a direction of core wire translation within the hollow guidewire. A method of treating a vascular condition and a guidewire-based embolic filter system are also disclosed.
摘要翻译： 一种用于治疗血管状态的系统，包括中空导丝，插入穿过中空导丝的芯线和栓塞容纳装置。 芯线包括承载在中空导丝内的锥形波状部分。 栓塞容纳装置联接在中空导丝的远端和芯线的远端之间。 芯线的锥形波动部分基于中空导丝内芯线平移的方向提供栓塞容纳装置的摩擦控制。 还公开了治疗血管病症的方法和基于导丝的栓塞过滤系统。
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公开(公告)号：US5746701A
公开(公告)日：1998-05-05
申请号：US528035
申请日：1995-09-14
申请人： Michael S. Noone
发明人： Michael S. Noone
CPC分类号： A61M25/09 , A61M2025/09083 , A61M25/0054 , A61M25/0138
摘要： The present invention relates to a guidewire which comprises an elongated core of a substantially solid cross-section having a distal end portion, the distal end portion having a plurality of notches therein, the notches having a depth of 5-25% of the diameter of the proximal end. The proximal end of the guidewire has a diameter in the range of 0.005-0.040 inches, the notches defining a continuous helix with a constant depth. The guidewire also comprises a helically wound spring, the spring having a plurality of coils defining a lumen. At least part of the distal end portion of the elongated core being received within the lumen. That part of the distal end portion of the elongated core being received within the lumen forming with the helically wound spring an intermediate portion, at least a portion of the coils being disposed within the continuous helix of the elongated core, the helically wound spring being sized and positioned on the elongated core such that a smooth continuous outer diameter is attained over the length of the guidewire. The guidewire also has a means for bonding the coils to the distal end portion so that the guidewire has a continuous stiffness gradient along the length of the guidewire from a stiffest point at the proximal end to a more flexible portion in the distal end portion proximal to the intermediate portion, to a still more flexible portion in the intermediate portion to a most flexible point at the distal end of the helically wound spring. In an alternative embodiment the notches define a continuous helix with a constant depth. This alternative embodiment also has a rounded tip connected to the distal end of the spring and a safety wire connecting the distal end portion and the rounded tip.
摘要翻译： 本发明涉及一种导线，其包括具有远端部分的基本上实心的横截面的细长芯，所述远端部分在其中具有多个凹口，所述凹口的深度为直径的5-25％ 近端。 导线的近端具有在0.005-0.040英寸范围内的直径，凹口限定具有恒定深度的连续螺旋。 导丝还包括螺旋缠绕的弹簧，弹簧具有限定内腔的多个线圈。 细长芯的远端部分的至少一部分被容纳在内腔内。 细长芯的远端部分的部分被容纳在内腔内，螺旋缠绕的弹簧形成中间部分，至少一部分线圈设置在细长芯的连续螺旋内，螺旋形缠绕的弹簧的尺寸 并且定位在细长芯上，使得在导丝的长度上获得平滑的连续外径。 导线还具有用于将线圈接合到远端部分的装置，使得导丝线沿着导丝的长度具有从近端的最刚点到在近端的远端部分中的更柔性部分的连续刚度梯度 中间部分延伸到中间部分中更柔性的部分，到螺旋形弹簧的远端处的最柔软的点。 在替代实施例中，凹口限定具有恒定深度的连续螺旋。 该替代实施例还具有连接到弹簧的远端的圆形末端和连接远端部分和圆形末端的安全线。
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公开(公告)号：US20090137982A1
公开(公告)日：2009-05-28
申请号：US12325547
申请日：2008-12-01
申请人： Michael S. Noone
发明人： Michael S. Noone
IPC分类号： A61M29/00
CPC分类号： A61M25/10 , A61M2025/0681 , A61M2025/1052
摘要： A guiding catheter for providing proximal occlusion while intubating a branch vessel lumen in a patient. The catheter comprises an elongate hollow shaft having open proximal and distal ends and a resiliently compressible occluder fixed about the shaft adjacent the distal end, the occluder having a relaxed shape that tapers distally from a major diameter greater than a diameter of the vessel lumen. The occluder may comprise elastic foam material or an impermeable flexible cover clingingly enclosing a resilient support member.
摘要翻译： 用于在插管患者中的分支血管腔时提供近端闭塞的引导导管。 导管包括具有开放的近端和远端的细长空心轴和邻近远端固定在轴上的可弹性压缩的闭塞器，所述闭塞器具有从大于血管腔直径的大直径向远端渐缩的松弛形状。 封堵器可以包括弹性泡沫材料或密封地包围弹性支撑构件的不可渗透的柔性盖。
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公开(公告)号：US07294135B2
公开(公告)日：2007-11-13
申请号：US10392517
申请日：2003-03-20
申请人： Adam Stephens , Kazuna Tanaka , Jeffrey Kapec , Peter George Strickler , Nasser Rafiee , Steven Dapolito , Michael S. Noone
发明人： Adam Stephens , Kazuna Tanaka , Jeffrey Kapec , Peter George Strickler , Nasser Rafiee , Steven Dapolito , Michael S. Noone
CPC分类号： A61F2/013 , A61F2002/011 , A61F2002/9517 , A61F2230/0006 , A61M25/0136
摘要： A control handle for an intraluminal device includes a handle housing having a first end and a second end, the handle housing having a lumen. A roller assembly is disposed at a first end of the lumen. The roller assembly comprises a first roller and a base. The lumen is interposed between the first roller and the base. A clamp assembly is disposed at the second end of the lumen. The clamp assembly comprises a first clamp element and a second clamp element. The lumen is interposed between the first clamp element and the second clamp element. A closure mechanism is configured to effect movement between the first clamp element and the second clamp element and between the first roller and the base. The control handle further includes a turn device operably connected to the roller assembly.
摘要翻译： 用于管腔内装置的控制手柄包括具有第一端和第二端的手柄壳体，手柄壳体具有内腔。 辊组件设置在内腔的第一端。 辊组件包括第一辊和底座。 管腔介于第一辊和底座之间。 夹具组件设置在管腔的第二端。 夹具组件包括第一夹紧元件和第二夹紧元件。 管腔介于第一夹紧元件和第二夹紧元件之间。 闭合机构构造成实现第一夹紧元件和第二夹紧元件之间以及第一滚子与底座之间的移动。 控制手柄还包括可操作地连接到辊组件的转向装置。
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