专利检索 ap:("Michael Soeberdt" OR "Philip Weyermann" OR "Andreas Von Sprecher") AND inv:"Philip Weyermann" 第 1 页

1.

发明申请
Substituted piperidine and piperazine derivatives as melanocortin-4 receptor modulators 审中-公开

公开(公告)号：US20060276485A1

公开(公告)日：2006-12-07

申请号：US10550222

申请日：2004-03-19

申请人： Michael Soeberdt , Philip Weyermann , Andreas Von Sprecher

发明人： Michael Soeberdt , Philip Weyermann , Andreas Von Sprecher

IPC分类号： A61K31/496 , A61K31/4709 , A61K31/454 , C07D405/14 , C07D403/14

CPC分类号： C07D401/12 , C07D405/12

摘要： The present invention relates to novel substituted piperidine and piperazine derivatives as melanocortin-4 receptor (MC-4R) modulators. MC-4R agonists of the invention can be used for the treatment of disorders and diseases such as obesity, diabetes, and sexual dysfunction, whereas the MC-4R antagonists are useful for the treatment of disorders and diseases such as cancer cachexia, muscle wasting, anorexia, anxiety and depression. All diseases and disorders where the regulation of the MC-4R is involved can be treated with the compounds of the invention.