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公开(公告)号：US07205118B2
公开(公告)日：2007-04-17
申请号：US11152765
申请日：2005-06-14
申请人： Michael Tacke , Peter Berndt , Marie-Luise Hagmann , Johann Karl , Theresa Kott , Hanno Langen , Stefan Palme , Markus Roessler , Wolfgang Rollinger , Werner Zolg
发明人： Michael Tacke , Peter Berndt , Marie-Luise Hagmann , Johann Karl , Theresa Kott , Hanno Langen , Stefan Palme , Markus Roessler , Wolfgang Rollinger , Werner Zolg
IPC分类号： G01N33/53
CPC分类号： G01N33/57419 , C12Q1/48
摘要： The present invention relates to the diagnosis of colorectal cancer. It discloses the use of the protein nicotinamide N-methyltransferase (NNMT) in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring NNMT in said sample. Measurement of NNMT can, e.g., be used in the early detection or diagnosis of colorectal cancer.
摘要翻译： 本发明涉及结肠直肠癌的诊断。 它公开了蛋白质烟酰胺N-甲基转移酶（NNMT）在结肠直肠癌诊断中的应用。 本发明涉及通过在所述样品中测量NNMT从个体衍生的液体样品中诊断结肠直肠癌的方法。 NNMT的测定可以例如用于结肠直肠癌的早期检测或诊断。
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公开(公告)号：US20060003368A1
公开(公告)日：2006-01-05
申请号：US11152765
申请日：2005-06-14
申请人： Michael Tacke , Peter Berndt , Marie-Luise Hagmann , Johann Karl , Theresa Kott , Hanno Langen , Stefan Palme , Markus Roessler , Wolfgang Rollinger , Werner Zolg
发明人： Michael Tacke , Peter Berndt , Marie-Luise Hagmann , Johann Karl , Theresa Kott , Hanno Langen , Stefan Palme , Markus Roessler , Wolfgang Rollinger , Werner Zolg
IPC分类号： C12Q1/68 , G01N33/574
CPC分类号： G01N33/57419 , C12Q1/48
摘要： The present invention relates to the diagnosis of colorectal cancer. It discloses the use of the protein nicotinamide N-methyltransferase (NNMT) in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring NNMT in said sample. Measurement of NNMT can, e.g., be used in the early detection or diagnosis of colorectal cancer.
摘要翻译： 本发明涉及结肠直肠癌的诊断。 它公开了蛋白质烟酰胺N-甲基转移酶（NNMT）在结肠直肠癌诊断中的应用。 本发明涉及通过在所述样品中测量NNMT从个体衍生的液体样品中诊断结肠直肠癌的方法。 NNMT的测定可以例如用于结肠直肠癌的早期检测或诊断。
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公开(公告)号：US20060194266A1
公开(公告)日：2006-08-31
申请号：US11348889
申请日：2006-02-07
申请人： Michael Tacke , Peter Berndt , Marie-Luise Hagmann , Johann Karl , Hanno Langen , Stefan Palme , Markus Roessler , Wolfgang Rollinger , Werner Zolg
发明人： Michael Tacke , Peter Berndt , Marie-Luise Hagmann , Johann Karl , Hanno Langen , Stefan Palme , Markus Roessler , Wolfgang Rollinger , Werner Zolg
IPC分类号： G01N33/574
CPC分类号： G01N33/57419
摘要： The present invention relates to the diagnosis of colorectal cancer. It discloses the use of protein RLA-0 (60S acidic ribosomal protein P0) in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring RLA-0 in said sample. Measurement of RLA-0 can, e.g., be used in the early detection or diagnosis of colorectal cancer.
摘要翻译： 本发明涉及结肠直肠癌的诊断。 它公开了蛋白质RLA-0（60S酸性核糖体蛋白质P0）在结直肠癌诊断中的应用。 本发明涉及通过测量所述样品中的RLA-0从个体获得的来自液体样品的结肠直肠癌的诊断方法。 RLA-0的测定可以例如用于结肠直肠癌的早期检测或诊断。
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公开(公告)号：US20060121540A1
公开(公告)日：2006-06-08
申请号：US11287575
申请日：2005-11-23
申请人： Michael Tacke , Peter Berndt , Marie-Luise Hagmann , Johann Karl , Hanno Langen , Stefan Palme , Markus Roessler , Wolfgang Rollinger , Werner Zolg
发明人： Michael Tacke , Peter Berndt , Marie-Luise Hagmann , Johann Karl , Hanno Langen , Stefan Palme , Markus Roessler , Wolfgang Rollinger , Werner Zolg
IPC分类号： G01N33/574
CPC分类号： G01N33/57419 , G01N2333/8107 , G01N2800/52
摘要： The present invention relates to the diagnosis of colorectal cancer. It discloses the use of protein MASP in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring MASP in said sample. Measurement of MASP can, e.g., be used in the early detection or diagnosis of colorectal cancer.
摘要翻译： 本发明涉及结肠直肠癌的诊断。 它公开了蛋白质MASP在结直肠癌诊断中的应用。 本发明涉及一种通过测量所述样品中的MASP从个体获得的来自液体样品的结肠直肠癌的诊断方法。 MASP的测量可以例如用于结肠直肠癌的早期检测或诊断。
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公开(公告)号：US20070218510A1
公开(公告)日：2007-09-20
申请号：US11348865
申请日：2006-02-07
申请人： Michael Tacke , Peter Berndt , Marie-Luise Hagmann , Johann Karl , Hanno Langen , Stefan Palme , Markus Roessler , Wolfgang Rollinger , Werner Zolg
发明人： Michael Tacke , Peter Berndt , Marie-Luise Hagmann , Johann Karl , Hanno Langen , Stefan Palme , Markus Roessler , Wolfgang Rollinger , Werner Zolg
IPC分类号： G01N33/574
CPC分类号： G01N33/57419 , G01N2333/95
摘要： The present invention relates to the diagnosis of colorectal cancer. It discloses the use of protein proteasome subunit alpha 3 (PSA3) in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring PSA3 in said sample. Measurement of PSA3 can, e.g., be used in the early detection or diagnosis of colorectal cancer.
摘要翻译： 本发明涉及结肠直肠癌的诊断。 它公开了蛋白质蛋白酶体亚单位α3（PSA3）在结肠直肠癌诊断中的应用。 本发明涉及通过测量所述样品中的PSA3从来自个体的液体样品诊断结肠直肠癌的方法。 PSA3的测定可以例如用于结肠直肠癌的早期检测或诊断。
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公开(公告)号：US20060188950A1
公开(公告)日：2006-08-24
申请号：US11348932
申请日：2006-02-07
申请人： Michael Tacke , Peter Berndt , Marie-Luise Hagmann , Johann Karl , Hanno Langen , Stefan Palme , Markus Roessler , Wolfgang Rollinger , Werner Zolg
发明人： Michael Tacke , Peter Berndt , Marie-Luise Hagmann , Johann Karl , Hanno Langen , Stefan Palme , Markus Roessler , Wolfgang Rollinger , Werner Zolg
IPC分类号： G01N33/574
CPC分类号： G01N33/57419 , G01N2333/91171
摘要： The present invention relates to the diagnosis of colorectal cancer. It discloses the use of protein SPEE (sperrnidine synthase) in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring SPEE in said sample. Measurement of SPEE can, e.g., be used in the early detection or diagnosis of colorectal cancer.
摘要翻译： 本发明涉及结肠直肠癌的诊断。 它公开了蛋白质SPEE（精氨酸合酶）在结肠直肠癌诊断中的应用。 本发明涉及一种通过测量所述样品中的SPEE从来自个体的液体样品诊断结肠直肠癌的方法。 SPEE的测量可以例如用于结肠直肠癌的早期检测或诊断。
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公开(公告)号：US20060199232A1
公开(公告)日：2006-09-07
申请号：US11348950
申请日：2006-02-07
申请人： Michael Tacke , Peter Berndt , Marie-Luise Hagmann , Johann Karl , Hanno Langen , Stefan Palme , Markus Roessler , Wolfgang Rollinger , Werner Zolg
发明人： Michael Tacke , Peter Berndt , Marie-Luise Hagmann , Johann Karl , Hanno Langen , Stefan Palme , Markus Roessler , Wolfgang Rollinger , Werner Zolg
IPC分类号： G01N33/574
CPC分类号： G01N33/57419
摘要： The present invention relates to the diagnosis of colorectal cancer. It discloses the use of protein PSE3 (proteasome activator subunit 3) in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring PSE3 in said sample. Measurement of PSE3 can, e.g., be used in the early detection or diagnosis of colorectal cancer.
摘要翻译： 本发明涉及结肠直肠癌的诊断。 它公开了蛋白质PSE3（蛋白酶体激活子亚基3）在结肠直肠癌诊断中的应用。 本发明涉及通过测量所述样品中的PSE3从个体衍生的液体样品中诊断结肠直肠癌的方法。 PSE3的测定可以例如用于结肠直肠癌的早期检测或诊断。
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公开(公告)号：US20060188949A1
公开(公告)日：2006-08-24
申请号：US11348841
申请日：2006-02-07
申请人： Michael Tacke , Peter Berndt , Marie-Luise Hagmann , Johann Karl , Hanno Langen , Stefan Palme , Markus Roessler , Wolfgang Rollinger , Werner Zolg
发明人： Michael Tacke , Peter Berndt , Marie-Luise Hagmann , Johann Karl , Hanno Langen , Stefan Palme , Markus Roessler , Wolfgang Rollinger , Werner Zolg
IPC分类号： G01N33/574
CPC分类号： G01N33/57419
摘要： The present invention relates to the diagnosis of colorectal cancer. It discloses the use of protein PLST (T-plastin) in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring PLST in said sample. Measurement of PLST can, e.g., be used in the early detection or diagnosis of colorectal cancer.
摘要翻译： 本发明涉及结肠直肠癌的诊断。 它公开了蛋白质PLST（T-plastin）在结肠直肠癌诊断中的应用。 本发明涉及通过测量所述样品中的PLST从来自个体的液体样品诊断结肠直肠癌的方法。 PLST的测量可以例如用于结肠直肠癌的早期检测或诊断。
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公开(公告)号：US20060177880A1
公开(公告)日：2006-08-10
申请号：US11336707
申请日：2006-01-20
申请人： Michael Tacke , Peter Berndt , Marie-Luise Hagmann , Hanno Langen , Stefan Palme , Markus Roessler , Wolfgang Rollinger , Werner Zolg , Johann Karl
发明人： Michael Tacke , Peter Berndt , Marie-Luise Hagmann , Hanno Langen , Stefan Palme , Markus Roessler , Wolfgang Rollinger , Werner Zolg , Johann Karl
IPC分类号： G01N33/574 , G01N33/537
CPC分类号： G01N33/57419 , G01N2333/8121 , G01N2333/96433
摘要： The present invention relates to the diagnosis of colorectal cancer. It discloses the use of protein PRN3/ILEU and/or unbound PRN3 in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring PRN3/ILEU and/or unbound PRN3 in said sample. Measurement of PRN3/ILEU and/or unbound PRN3 can, e.g., be used in the early detection or diagnosis of colorectal cancer.
摘要翻译： 本发明涉及结肠直肠癌的诊断。 它公开了蛋白质PRN3 / ILEU和/或未结合的PRN3在结肠直肠癌诊断中的应用。 本发明涉及通过在所述样品中测量PRN3 / ILEU和/或未结合的PRN3从来自个体的液体样品诊断结肠直肠癌的方法。 PRN3 / ILEU和/或未结合的PRN3的测量可以例如用于结肠直肠癌的早期检测或诊断。
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公开(公告)号：US20070161062A1
公开(公告)日：2007-07-12
申请号：US11640511
申请日：2006-12-15
申请人： Michael Tacke , Marie-Luise Hagmann , Johann Karl , Stefan Palme , Michael Pfeffer , Wolfgang Rollinger , Michael Thierolf , Werner Zolg
发明人： Michael Tacke , Marie-Luise Hagmann , Johann Karl , Stefan Palme , Michael Pfeffer , Wolfgang Rollinger , Michael Thierolf , Werner Zolg
IPC分类号： G01N33/574
CPC分类号： G01N33/57419 , G01N2333/8121
摘要： The present invention relates to the diagnosis of colorectal cancer. It discloses the use of protein CBP2 (collagen-binding protein 2) in the diagnosis of colorectal cancer. It relates to a method for diagnosis of colorectal cancer from a liquid sample, derived from an individual by measuring CBP2 in said sample. Measurement of CBP2 can, e.g., be used in the early detection or diagnosis of colorectal cancer.
摘要翻译： 本发明涉及结肠直肠癌的诊断。 它公开了蛋白质CBP2（胶原结合蛋白2）在结肠直肠癌诊断中的应用。 它涉及通过测量所述样品中的CBP2从来自个体的液体样品诊断结肠直肠癌的方法。 CBP2的测定可以例如用于结肠直肠癌的早期检测或诊断。
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