Methods of disinfecting, disinfectants and pharmacetical composition
comprising azoic compound
    2.
    发明授权
    Methods of disinfecting, disinfectants and pharmacetical composition comprising azoic compound 失效
    消毒剂,消毒剂和含有偶氮化合物的药物组合物的方法

    公开(公告)号:US5399555A

    公开(公告)日:1995-03-21

    申请号:US947090

    申请日:1992-09-17

    CPC分类号: A61K31/655

    摘要: Compositions useful in methods of disinfecting contain azoic compounds of the general formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are identical or different and each represents an atom of hydrogen or an aliphatic or aromatic hydrocarbon radical comprising from 1 to 6 carbon atoms; X.sup.1 and X.sup.2 are identical or different and each represents an oxygen atom or an NR.sup.5 group, wherein R.sup.5 is a hydrogen atom, an aliphatic or aromatic hydrocarbon radical comprising from 1 to 6 carbon atoms, or a nitro group; and wherein when two NR.sup.5 groups are simultaneously present each R.sup.5 may be identical to or different from the other. Compositions containing the azoic compounds in a liquid medium at concentrations of from 35 .mu.gr/ml to 2 mgr/ml are sufficient to impede replication and proliferation of viruses of the retrovirus group yet they are insufficiently toxic to destroy sound human or animal cells which come in contact with the compositions. Methods of disinfecting using the compositions are also provided.

    摘要翻译: 用于消毒方法的组合物含有通式为“IMAGE”的偶氮化合物,其中R 1,R 2,R 3和R 4相同或不同,并且各自表示氢原子或含有1至6个碳原子的脂族或芳族烃基; X 1和X 2相同或不同,各自表示氧原子或NR 5基团,其中R 5是氢原子,含有1至6个碳原子的脂族或芳族烃基或硝基; 并且其中当两个NR 5基团同时存在时,每个R 5可以与另一个相同或不同。 在液体培养基中含有浓度为35μg/ ml至2mgr / ml的偶氮化合物的组合物足以阻止逆转录病毒组病毒的复制和增殖,但它们毒性不足以破坏出现的健康的人或动物细胞 与组合物接触。 还提供了使用组合物消毒的方法。