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公开(公告)号：US08568797B2
公开(公告)日：2013-10-29
申请号：US13231329
申请日：2011-09-13
申请人： Michele C. Duggan , Satish Parimoo , Cheng Hwang
发明人： Michele C. Duggan , Satish Parimoo , Cheng Hwang
IPC分类号： A61K36/00
CPC分类号： A61K8/49 , A61K8/342 , A61K8/97 , A61K31/045 , A61K31/426 , A61K36/185 , A61K38/06 , A61K45/06 , A61Q7/00 , A61K2300/00
摘要： New fibroblast growth factor receptor 1 (FGFR1) inhibitors have been identified which are useful for promoting the retention and/or growth of keratin fibers, such as hair of the scalp, hair of the face (moustache, beard, etc.), eyebrows, eyelashes, and the like. The FGFR1 inhibitors may be formulated in effective amounts in a variety of cosmetic and personal care products.
摘要翻译： 已经鉴定了新的成纤维细胞生长因子受体1（FGFR1）抑制剂，其可用于促进角蛋白纤维的保留和/或生长，例如头皮毛发，面部毛发（胡子，胡须等），眉毛， 睫毛等。 FGFR1抑制剂可以有效量配制在各种化妆品和个人护理产品中。
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公开(公告)号：US20130064905A1
公开(公告)日：2013-03-14
申请号：US13231329
申请日：2011-09-13
申请人： Michele C. Duggan , Satish Parimoo , Cheng Hwang
发明人： Michele C. Duggan , Satish Parimoo , Cheng Hwang
IPC分类号： A61K36/00 , A61P17/14 , A61K38/06 , A61K31/426 , A61K31/045 , A61K31/195
CPC分类号： A61K8/49 , A61K8/342 , A61K8/97 , A61K31/045 , A61K31/426 , A61K36/185 , A61K38/06 , A61K45/06 , A61Q7/00 , A61K2300/00
摘要： New fibroblast growth factor receptor 1 (FGFR1) inhibitors have been identified which are useful for promoting the retention and/or growth of keratin fibers, such as hair of the scalp, hair of the face (moustache, beard, etc.), eyebrows, eyelashes, and the like. The FGFR1 inhibitors may be formulated in effective amounts in a variety of cosmetic and personal care products.
摘要翻译： 已经鉴定了新的成纤维细胞生长因子受体1（FGFR1）抑制剂，其可用于促进角蛋白纤维的保留和/或生长，例如头皮毛发，面部毛发（胡子，胡须等），眉毛， 睫毛等。 FGFR1抑制剂可以有效量配制在各种化妆品和个人护理产品中。
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公开(公告)号：US20120110752A1
公开(公告)日：2012-05-10
申请号：US12940805
申请日：2010-11-05
CPC分类号： A61Q5/004 , A61K8/0241 , A61K8/25 , A61K8/585 , A61K8/89 , A61K2800/412 , A61K2800/612
摘要： Compositions and methods are disclosed for preventing or reducing loss of color from color-treated keratin fibers by forming a water-resistant coating on hair comprise a combination of a hydrophobic particulate material comprising a hydrophobically surface-modified oxide and one or more hydrophobic film formers in a cosmetically acceptable vehicle.
摘要翻译： 公开的组合物和方法用于通过在头发上形成防水涂层来防止或减少来自经色处理的角蛋白纤维的颜色损失，其包含疏水性颗粒材料与疏水性表面改性氧化物和一种或多种疏水性成膜剂的组合 美容上可接受的车辆。
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公开(公告)号：US07618662B2
公开(公告)日：2009-11-17
申请号：US11021047
申请日：2004-12-22
CPC分类号： A61K8/97 , A61K36/185 , A61K36/19 , A61K36/48 , A61K36/67 , A61K36/888 , A61Q19/06 , A61K2300/00
摘要： The present invention describes compositions and methods for treating, preventing and improving the appearance of skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating loss of subcutaneous fat in the skin, wherein the compositions include natural plant constituents that stimulate lipid synthesis. The plant extracts are preferably derived from Rhinacanthus nasutus, Humulus scandens, Sesbania grandiflora, Amorphophallus campanulatu, Pouzolzia pentandra, and Piper betel, and any combinations thereof. The compositions are preferably applied to the skin, or are delivered by directed means, to a site in need thereof.
摘要翻译： 本发明描述了用于治疗，预防和改善皮肤外观的组合物和方法，特别是治疗，预防，改善，减少和/或消除皮肤中皮下脂肪的损失，其中组合物包括刺激脂质合成的天然植物成分 。 植物提取物优选衍生自Rhinacanthus nasutus，Humulus scandens，Sesbania grandiflora，Amorphophallus campanulatu，Pouzolzia pentandra和Piper槟榔及其任何组合。 组合物优选施用于皮肤，或通过定向方式递送至有需要的部位。
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公开(公告)号：US06299889B1
公开(公告)日：2001-10-09
申请号：US09150806
申请日：1998-09-10
IPC分类号： A61K600
CPC分类号： A61K8/345 , A61K8/19 , A61K8/20 , A61K8/27 , A61K8/37 , A61K8/676 , A61K31/375 , A61K45/06 , A61Q19/10 , Y10S514/844 , A61K2300/00
摘要： Stable cosmetic compositions containing high levels of ascorbic acid, relatively low levels of water, varying levels of polyhydric alcohol, and organic carbonate are disclosed. The compositions may also include monohydric alcohol or hydroxyalkyl cellulose or both. The compositions are homogeneous solutions, and can be adapted to be topically applied to the skin to impart appearance benefits thereto.
摘要翻译： 公开了含有高水平的抗坏血酸，相对低水平的水，不同含量的多元醇和有机碳酸盐的稳定的化妆品组合物。 组合物还可以包括一元醇或羟烷基纤维素或两者。 组合物是均匀溶液，并且可以适于局部施用于皮肤以赋予其外观有益效果。
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公开(公告)号：US07939489B2
公开(公告)日：2011-05-10
申请号：US10328204
申请日：2002-12-23
申请人： Arvind Shah , Gopinathan K. Menon , Derrick B. McKie , Vincent T. Polywoda , Christos D. Kyrou , Michele C. Duggan
发明人： Arvind Shah , Gopinathan K. Menon , Derrick B. McKie , Vincent T. Polywoda , Christos D. Kyrou , Michele C. Duggan
IPC分类号： A61K9/00
CPC分类号： A61Q19/008 , A61K8/26 , A61K8/31 , A61K8/90 , A61Q1/14 , A61Q3/04 , A61Q5/00 , A61Q5/008 , A61Q19/00
摘要： There are provided topical compositions and methods for cleaning oil from the skin, nail or hair. The compositions have a vehicle and an effective amount of an oil-absorbing ingredient having an ethylene mixed block copolymer. There is also provided compositions and methods for treating acne, acne-related conditions, acne-prone skin and blemishes.
摘要翻译： 提供了用于从皮肤，指甲或头发清洁油的局部组合物和方法。 该组合物具有载体和有效量的具有乙烯混合嵌段共聚物的吸油成分。 还提供了治疗痤疮，痤疮相关病症，易痤疮皮肤和瑕疵的组合物和方法。
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公开(公告)号：US07074420B2
公开(公告)日：2006-07-11
申请号：US10288603
申请日：2002-11-05
CPC分类号： A61Q19/005 , A61K8/671 , A61Q19/08
摘要： There is provided a topical composition and method for improving the aesthetic appearance of skin, particularly, preventing, ameliorating, treating and/or reducing fine lines and/or wrinkles, without the skin irritation typically associated with topical application of a retinoid. There is also provided a topical composition and method for improving the aesthetic appearance of lips, particularly decreasing the number and/or depth of vertical lip lines. The composition has an effective amount of retinoxytrimethylsilane. Preferably, the composition is applied daily to skin and/or lips. The composition and method are particularly suitable for persons having sensitive skin.
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8.发明授权Compositions and delivery methods for the treatment of wrinkles, fine lines and hyperhidrosis 有权用于治疗皱纹，细纹和多汗症的组合物和递送方法公开(公告)号：US06866856B2
公开(公告)日：2005-03-15
申请号：US10334887
申请日：2002-12-31
IPC分类号： A61K8/04 , A61K8/14 , A61K8/97 , A61K31/00 , A61K31/01 , A61K31/045 , A61K31/365 , A61K36/752 , A61K45/06 , A61Q19/08 , A61K7/00
CPC分类号： A61Q19/08 , A61K8/046 , A61K8/14 , A61K8/97 , A61K31/00 , A61K31/01 , A61K31/045 , A61K31/365 , A61K45/06 , A61K2800/70 , A61K2300/00
摘要： The present invention describes compositions and methods for treating, preventing and improving the appearance of skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating fine lines and/or wrinkles of skin, wherein the compositions include limonoid constituents which inhibit acetylcholine release at neuromuscular junctions of skeletal muscle so as to relax the muscles involved with wrinkling, folding and creasing of skin, e.g., facial movement and expression. The limonoids preferably include the plant alkaloids toosendanin and azadirachtin. The compositions, which also are used to treat hyperhidrosis, are preferably applied to the skin, or are delivered by directed means to a site in need thereof.
摘要翻译： 本发明描述了用于治疗，预防和改善皮肤外观，特别是治疗，预防，改善，减少和/或消除皮肤细纹和/或皱纹的组合物和方法，其中组合物包括抑制乙酰胆碱释放的柠檬醛成分 在骨骼肌的神经肌肉接头处，以便放松与皮肤起皱，折叠和皱纹相关的肌肉，例如面部运动和表达。 柠檬醛优选包括植物生物碱toosendanin和印苦楝子素。 也用于治疗多汗症的组合物优选施用于皮肤，或通过定向方式递送至有需要的部位。
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9.发明授权Compositions having comfrey and methods for reducing retinoid-induced skin irritation 失效具有康普的组合物和减少类视黄醇诱导的皮肤刺激的方法公开(公告)号：US06583184B1
公开(公告)日：2003-06-24
申请号：US09722782
申请日：2000-11-27
申请人： Michele C. Duggan
发明人： Michele C. Duggan
IPC分类号： A01N2500
CPC分类号： A61K31/07 , A61K36/30 , A61K2300/00
摘要： There is provided a topical composition for treating and/or preventing skin irritation induced by a retinoid. The composition has comfrey. There is also provided a method for treating and/or preventing skin irritation induced by a retinoid. An effective amount of comfrey is applied to the skin.
摘要翻译： 提供了用于治疗和/或预防类视黄醇诱导的皮肤刺激的局部组合物。 该组合物具有紫草。 还提供了治疗和/或预防类视黄醇诱导的皮肤刺激的方法。 将有效量的紫草应用于皮肤。
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