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1.发明授权Compositions and delivery methods for the treatment of wrinkles, fine lines and hyperhidrosis 有权用于治疗皱纹，细纹和多汗症的组合物和递送方法公开(公告)号：US06866856B2
公开(公告)日：2005-03-15
申请号：US10334887
申请日：2002-12-31
IPC分类号： A61K8/04 , A61K8/14 , A61K8/97 , A61K31/00 , A61K31/01 , A61K31/045 , A61K31/365 , A61K36/752 , A61K45/06 , A61Q19/08 , A61K7/00
CPC分类号： A61Q19/08 , A61K8/046 , A61K8/14 , A61K8/97 , A61K31/00 , A61K31/01 , A61K31/045 , A61K31/365 , A61K45/06 , A61K2800/70 , A61K2300/00
摘要： The present invention describes compositions and methods for treating, preventing and improving the appearance of skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating fine lines and/or wrinkles of skin, wherein the compositions include limonoid constituents which inhibit acetylcholine release at neuromuscular junctions of skeletal muscle so as to relax the muscles involved with wrinkling, folding and creasing of skin, e.g., facial movement and expression. The limonoids preferably include the plant alkaloids toosendanin and azadirachtin. The compositions, which also are used to treat hyperhidrosis, are preferably applied to the skin, or are delivered by directed means to a site in need thereof.
摘要翻译： 本发明描述了用于治疗，预防和改善皮肤外观，特别是治疗，预防，改善，减少和/或消除皮肤细纹和/或皱纹的组合物和方法，其中组合物包括抑制乙酰胆碱释放的柠檬醛成分 在骨骼肌的神经肌肉接头处，以便放松与皮肤起皱，折叠和皱纹相关的肌肉，例如面部运动和表达。 柠檬醛优选包括植物生物碱toosendanin和印苦楝子素。 也用于治疗多汗症的组合物优选施用于皮肤，或通过定向方式递送至有需要的部位。
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公开(公告)号：US09956432B2
公开(公告)日：2018-05-01
申请号：US12940805
申请日：2010-11-05
CPC分类号： A61Q5/004 , A61K8/0241 , A61K8/25 , A61K8/585 , A61K8/89 , A61K2800/412 , A61K2800/612
摘要： Compositions and methods are disclosed for preventing or reducing loss of color from color-treated keratin fibers by forming a water-resistant coating on hair comprise a combination of a hydrophobic particulate material comprising a hydrophobically surface-modified oxide and one or more hydrophobic film formers in a cosmetically acceptable vehicle.
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公开(公告)号：US20120110752A1
公开(公告)日：2012-05-10
申请号：US12940805
申请日：2010-11-05
CPC分类号： A61Q5/004 , A61K8/0241 , A61K8/25 , A61K8/585 , A61K8/89 , A61K2800/412 , A61K2800/612
摘要： Compositions and methods are disclosed for preventing or reducing loss of color from color-treated keratin fibers by forming a water-resistant coating on hair comprise a combination of a hydrophobic particulate material comprising a hydrophobically surface-modified oxide and one or more hydrophobic film formers in a cosmetically acceptable vehicle.
摘要翻译： 公开的组合物和方法用于通过在头发上形成防水涂层来防止或减少来自经色处理的角蛋白纤维的颜色损失，其包含疏水性颗粒材料与疏水性表面改性氧化物和一种或多种疏水性成膜剂的组合 美容上可接受的车辆。
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公开(公告)号：US20120164093A1
公开(公告)日：2012-06-28
申请号：US12979539
申请日：2010-12-28
申请人： Thi N. Do , Freda E. Robinson , Robert E. Kalafsky
发明人： Thi N. Do , Freda E. Robinson , Robert E. Kalafsky
摘要： Fluids are provided which resist phase separation by inclusion of a stabilizing amount of a glutamic acid derivative in the presence of ethanol. The fluids comprise an aqueous discontinuous phase, a silicone oil containing continuous phase, a glutamic acid derivative such as dibutyl ethylhexanoyl glutamide, and ethanol. The fluids may be prepared without heating to solubilize the glutamic acid derivative
摘要翻译： 提供通过在乙醇存在下包含稳定量的谷氨酸衍生物来抵抗相分离的流体。 流体包含水不连续相，含有连续相的硅油，谷氨酸衍生物如二丁基乙基己酰基谷氨酰胺和乙醇。 可以不加热来制备流体来溶解谷氨酸衍生物
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公开(公告)号：USD434524S
公开(公告)日：2000-11-28
申请号：US99158
申请日：1999-01-14
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公开(公告)号：US08591871B2
公开(公告)日：2013-11-26
申请号：US12979539
申请日：2010-12-28
申请人： Thi N. Do , Freda E. Robinson , Robert E. Kalafsky
发明人： Thi N. Do , Freda E. Robinson , Robert E. Kalafsky
IPC分类号： A61Q5/00
摘要： Fluids are provided which resist phase separation by inclusion of a stabilizing amount of a glutamic acid derivative in the presence of ethanol. The fluids comprise an aqueous discontinuous phase, a silicone oil containing continuous phase, a glutamic acid derivative such as dibutyl ethylhexanoyl glutamide, and ethanol. The fluids may be prepared without heating to solubilize the glutamic acid derivative.
摘要翻译： 提供通过在乙醇存在下包含稳定量的谷氨酸衍生物来抵抗相分离的流体。 流体包含水不连续相，含有连续相的硅油，谷氨酸衍生物如二丁基乙基己酰基谷氨酰胺和乙醇。 可以不加热来制备流体来溶解谷氨酸衍生物。
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公开(公告)号：US07186404B2
公开(公告)日：2007-03-06
申请号：US11093217
申请日：2005-03-29
CPC分类号： A61K8/37 , A61K8/35 , A61K8/97 , A61K2800/52 , A61Q17/04
摘要： There is provided a photostable and synergistically enhanced topical sunscreen composition. There is further provided a method of enhancing the photostability of a sunscreen active in a topical sunscreen composition. There is further still provided a method of synergistically enhancing the UV absorbance of a sunscreen active in a topical sunscreen composition. The preferred compositions and methods of the present invention use a dibenzoylmethane sunscreen active, a Kaempferia galanga extract, and a cosmetically acceptable vehicle.
摘要翻译： 提供了光稳定和协同增强的局部防晒组合物。 还提供了一种提高局部防晒组合物中防晒活性物质的光稳定性的方法。 还提供了协同增强局部防晒组合物中防晒活性物质的紫外线吸收的方法。 本发明的优选组合物和方法使用二苯甲酰甲烷防晒活性物质，高山羊皮提取物和化妆品可接受的载体。
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8.发明授权Esters of aryl benzimidazole sulfonic acids and sunscreen compositions containing same 失效芳基苯并咪唑磺酸酯和含有它们的防晒组合物公开(公告)号：US07118760B2
公开(公告)日：2006-10-10
申请号：US10744875
申请日：2003-12-23
申请人： Anthony D. Gonzalez , Andrew H. Pechko , Glen T. Anderson , Robert E. Kalafsky , Michael V. Lowenborg
发明人： Anthony D. Gonzalez , Andrew H. Pechko , Glen T. Anderson , Robert E. Kalafsky , Michael V. Lowenborg
IPC分类号： A61K8/19 , A61K8/02 , A01N25/04 , C07D235/04
CPC分类号： C07D235/18 , A61K8/4946 , A61Q17/02 , A61Q17/04 , C07D235/20
摘要： The present invention provides novel aryl benzimidazole sulfonic acid esters and cosmetic compositions that employ the novel aryl benzimidazole sulfonic acid esters as sunscreens. The cosmetic compositions can be water, organic solvent or emulsion based. Also provided are methods of using the compositions to protect skin from exposure to the sun, and optionally, repel insects.
摘要翻译： 本发明提供使用新型芳基苯并咪唑磺酸酯作为防晒剂的新型芳基苯并咪唑磺酸酯和化妆品组合物。 化妆品组合物可以是水，有机溶剂或乳液。 还提供了使用组合物来保护皮肤免受暴露于太阳的任选方法，并且任选地排斥昆虫。
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9.发明授权Extended duration insect repellent composition and method of application to the skin 有权延长持续时间的驱虫剂组合物和施用于皮肤的方法公开(公告)号：US06719959B1
公开(公告)日：2004-04-13
申请号：US09724160
申请日：2000-11-28
IPC分类号： A01N2506
CPC分类号： A61Q17/02 , A01N25/06 , A01N25/10 , A01N25/22 , A01N25/24 , A01N31/06 , A01N37/18 , A01N37/46 , A01N47/16 , A01N61/00 , A01N65/08 , A01N65/20 , A01N65/44 , A61K8/345 , A61K8/42 , A61K8/44 , A61K8/4926 , A61K8/87 , A61K8/922 , Y02A50/34 , Y02A50/344 , Y02A50/348 , Y10S424/10 , Y10S514/919
摘要： Disclosed is an insect repellent composition. The composition has an amount of an insect repellent active effective to repel insects when the composition is applied to the skin, and an amount of a urethane polymer sufficient to form a film on the surface of the skin. The composition also has a cosmetically-acceptable vehicle. Also disclosed is a method of repelling insects from the skin by applying the composition to the skin.
摘要翻译： 披露了一种驱虫剂组合物。 该组合物具有一定量的有效抵抗昆虫的昆虫驱避剂，当将组合物施用于皮肤时，以及足以在皮肤表面形成膜的氨基甲酸酯聚合物的量。 该组合物还具有美容上可接受的载体。 还公开了通过将组合物施用于皮肤来驱除来自皮肤的昆虫的方法。
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公开(公告)号：US06531118B1
公开(公告)日：2003-03-11
申请号：US10014167
申请日：2001-12-11
IPC分类号： A61K742
CPC分类号： A61K8/49 , A61K2800/438 , A61Q5/00 , A61Q17/04 , A61Q19/00 , Y10S514/844 , Y10S514/937 , Y10S514/938
摘要： There are provided topical compositions having reversible visible change in color in response to change in light. The compositions comprise color changing capability provided by photochromic material and a vehicle acceptable for topical application to the skin or hair.
摘要翻译： 提供了响应于光的变化而具有可逆的可见颜色变化的局部组合物。 组合物包含由光致变色材料提供的变色能力和可局部施用于皮肤或毛发的载体。
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