公开(公告)号：US06548674B2

公开(公告)日：2003-04-15

申请号：US09799607

申请日：2001-03-07

申请人： Miho Kawauchi ,  Noritsugu Yamasaki ,  Mitsuru Ohno

发明人： Miho Kawauchi ,  Noritsugu Yamasaki ,  Mitsuru Ohno

IPC分类号： C07D40508

CPC分类号： C07D319/06 ,  C07C235/80

摘要： A 6-aminocarbonylmethyl-4H-2,3-dioxin-4-one compounds can be produced by reacting a 6-halomethyl-4H-2,3-dioxin-4-one compound with a primary or secondary amine and carbon monoxide. The reaction may be carried out in the presence of a catalyst comprising a platinum group metal. 3-oxopentanedicarboxylic acid monoamides and 3-oxopentanedicarboxylic acid amide esters can be are produced by reacting 6-aminocarbonylmethyl-4H-2,3-dioxin-4-one compound with an alcohol or water. Using such intermediates, 6-aminocarbonylmethyl-4H-2,3-dioxin-4-one compound, 3-oxopentanedicarboxylic acid amide esters can provide in an easy and simple and efficient manner.

摘要翻译： 6-氨基羰基甲基-4H-2,3-二恶英-4-酮化合物可以通过使6-卤代甲基-4H-2,3-二恶英-4-酮化合物与伯胺或仲胺和一氧化碳反应来制备。 反应可以在包含铂族金属的催化剂的存在下进行。 3-氧代戊二酸单酰胺和3-氧代戊二酰胺酯可以通过6-氨基羰基甲基-4H-2,3-二恶英-4-酮化合物与醇或水反应来制备。 使用这种中间体，6-氨基羰基甲基-4H-2,3-二恶英-4-酮化合物，3-氧代戊二酰胺酯可以容易且简单和有效地提供。

公开(公告)号：US06657069B2

公开(公告)日：2003-12-02

申请号：US10378726

申请日：2003-03-05

申请人： Miho Kawauchi ,  Noritsugu Yamasaki ,  Mitsuru Ohno

发明人： Miho Kawauchi ,  Noritsugu Yamasaki ,  Mitsuru Ohno

IPC分类号： C07D20700

CPC分类号： C07D319/06 ,  C07C235/80

摘要： A 6-aminocarbonylmethyl-4H-2,3-dioxin-4-one compounds can be produced by reacting a 6-halomethyl-4H-2,3-dioxin-4-one compound with a primary or secondary amine and carbon monoxide. The reaction may be carried out in the presence of a catalyst comprising a platinum group metal. 3-oxopentanedicarboxylic acid monoamides and 3-oxopentanedicarboxylic acid amide esters can be are produced by reacting 6-aminocarbonylmethyl-4H-2,3-dioxin-4-one compound with an alcohol or water. Using such intermediates, 6-aminocarbonylmethyl-4H-2,3-dioxin-4-one compound, 3-oxopentanedicarboxylic acid amide esters can provide in an easy and simple and efficient manner.