Amido compounds and process for producing the same
    1.
    发明授权
    Amido compounds and process for producing the same 失效
    酰胺化合物及其制备方法

    公开(公告)号:US06548674B2

    公开(公告)日:2003-04-15

    申请号:US09799607

    申请日:2001-03-07

    IPC分类号: C07D40508

    CPC分类号: C07D319/06 C07C235/80

    摘要: A 6-aminocarbonylmethyl-4H-2,3-dioxin-4-one compounds can be produced by reacting a 6-halomethyl-4H-2,3-dioxin-4-one compound with a primary or secondary amine and carbon monoxide. The reaction may be carried out in the presence of a catalyst comprising a platinum group metal. 3-oxopentanedicarboxylic acid monoamides and 3-oxopentanedicarboxylic acid amide esters can be are produced by reacting 6-aminocarbonylmethyl-4H-2,3-dioxin-4-one compound with an alcohol or water. Using such intermediates, 6-aminocarbonylmethyl-4H-2,3-dioxin-4-one compound, 3-oxopentanedicarboxylic acid amide esters can provide in an easy and simple and efficient manner.

    摘要翻译: 6-氨基羰基甲基-4H-2,3-二恶英-4-酮化合物可以通过使6-卤代甲基-4H-2,3-二恶英-4-酮化合物与伯胺或仲胺和一氧化碳反应来制备。 反应可以在包含铂族金属的催化剂的存在下进行。 3-氧代戊二酸单酰胺和3-氧代戊二酰胺酯可以通过6-氨基羰基甲基-4H-2,3-二恶英-4-酮化合物与醇或水反应来制备。 使用这种中间体,6-氨基羰基甲基-4H-2,3-二恶英-4-酮化合物,3-氧代戊二酰胺酯可以容易且简单和有效地提供。