公开(公告)号：US20140277273A1

公开(公告)日：2014-09-18

申请号：US13831655

申请日：2013-03-15

申请人： Min ZHAO ,  Junfeng FENG ,  Lei ZHANG

发明人： Min ZHAO ,  Junfeng FENG ,  Lei ZHANG

IPC分类号： A61N1/36

CPC分类号： A61N1/205 ,  A61B5/0476 ,  A61K35/30 ,  A61K38/18 ,  A61N1/36082 ,  A61N1/36103

摘要： Systems and methods are provided for migrating cells implanted or endogenous in tissue. The system may include first and second delivery electrodes configured for insertion in tissue and a direct current (DC) power source operatively coupled to the first and second delivery electrodes. The system further may include a programmable controller operatively coupled to the DC power source, wherein the programmable controller is programmed to direct the DC power source to deliver an electric field between the first delivery electrode and the second delivery electrode at a stimulation to nonstimulation ratio sufficient to cause the cells to migrate within tissue selectively.

摘要翻译： 提供系统和方法用于迁移组织中植入或内源性的细胞。 该系统可以包括构造成用于插入组织的第一和第二输送电极以及可操作地耦合到第一和第二输送电极的直流（DC）电源。 系统还可以包括可操作地耦合到DC电源的可编程控制器，其中可编程控制器被编程为引导DC电源在第一输送电极和第二输送电极之间传递电场，以刺激足够的非刺激比 以使细胞选择性地在组织内迁移。