METHOD AND APPARATUS FOR CLUSTERING GENE EXPRESSION PROFILES BY USING GENE ONTOLOGY
    1.
    发明申请
    METHOD AND APPARATUS FOR CLUSTERING GENE EXPRESSION PROFILES BY USING GENE ONTOLOGY 审中-公开
    通过使用基因本体聚集基因表达谱的方法和装置

    公开(公告)号:US20090112480A1

    公开(公告)日:2009-04-30

    申请号:US12053315

    申请日:2008-03-21

    IPC分类号: G01N33/48

    CPC分类号: G16B25/00 G16B5/00

    摘要: Provided are a method and apparatus for clustering gene expression profiles by using the Gene Ontology (GO). The method includes: selecting one or more GO terms from a GO tree; receiving gene expression data sets; classifying the gene expression data sets into groups according to the GO terms; firstly clustering gene expression data belonging to each of the groups based on a similarity of the gene expression data; and secondly clustering the gene expression data sets by using the result of the first clustering as a seed.

    摘要翻译: 提供了通过使用基因本体(GO)聚类基因表达谱的方法和装置。 该方法包括:从GO树中选择一个或多个GO条款; 接收基因表达数据集; 根据GO条款将基因表达数据集分为组; 首先基于基因表达数据的相似性对属于每个组的基因表达数据进行聚类; 其次使用第一次聚类的结果作为种子对基因表达数据集进行聚类。