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    Method for the treatment of acne and certain dosage forms thereof
    1.
    发明授权
    Method for the treatment of acne and certain dosage forms thereof 有权
    治疗痤疮的方法及其某些剂型

    公开(公告)号：US09192615B2

    公开(公告)日：2015-11-24

    申请号：US12536359

    申请日：2009-08-05

    申请人： Mitchell Wortzman ,  R. Todd Plott ,  Steven B. Newhard ,  David Watt

    发明人： Mitchell Wortzman ,  R. Todd Plott ,  Steven B. Newhard ,  David Watt

    IPC分类号： A61K31/65 ,  A61K9/20

    CPC分类号： A61K31/65 ,  A61K9/2018 ,  A61K9/2054

    摘要： An oral dosage form, including 65 mg of minocycline, an amount of lactose monohydrate, and an amount of hydroxypropylmethylcellulose. The hydroxypropylmethylcellulose is hydroxypropylmethylcellulose that is about 8.9+/−0.2% hydroxypropoxylated. An oral dosage form, including 115 mg of minocycline, an amount of lactose monohydrate, and an amount of hydroxypropylmethylcellulose. The hydroxypropylmethylcellulose is hydroxypropylmethylcellulose that is about 8.9+/−0.2% hydroxypropoxylated.

    摘要翻译： 口服剂型，包括65mg米诺环素，一定量的乳糖一水合物和一定量的羟丙基甲基纤维素。 羟丙基甲基纤维素是约8.9 +/- 0.2％羟基丙氧基化的羟丙基甲基纤维素。 口服剂型，包括115毫克米诺环素，一定量的乳糖一水合物和一定量的羟丙基甲基纤维素。 羟丙基甲基纤维素是约8.9 +/- 0.2％羟基丙氧基化的羟丙基甲基纤维素。

    Extended-release minocycline dosage forms
    2.
    发明授权
    Extended-release minocycline dosage forms 有权
    延长释放米诺环素剂型

    公开(公告)号：US08722650B1

    公开(公告)日：2014-05-13

    申请号：US12861424

    申请日：2010-08-23

    申请人： Mitchell Wortzman ,  R. Todd Plott ,  Steven B. Newhard ,  David Watt

    发明人： Mitchell Wortzman ,  R. Todd Plott ,  Steven B. Newhard ,  David Watt

    IPC分类号： A61K9/16 ,  A61K9/50 ,  A61K9/52 ,  A61K9/54 ,  A61K31/65

    CPC分类号： A61K31/65

    摘要： An oral dosage form has the following: an amount of minocycline selected from the group consisting of 55 mg, 80 mg, and 105 mg; an amount of lactose monohydrate; an amount of hydroxypropylmethylcellulose. The hydroxypropylmethylcellulose is at least 8.3 to about 9.8% hydroxypropoxylated. The minocycline in the oral dosage form has a dissolution profile or release rates about 35% to about 50% in 1 hour, about 60% to about 75% in 2 hours, and at least about 90% in 4 hours. There is also provided a method of treating acne in a human and a method of assisting a physician in prescribing a dose of minocycline for the treatment of acne.

    摘要翻译： 口服剂型如下：一种选自55mg，80mg和105mg的米诺环素的量; 一定量的乳糖一水合物; 一定量的羟丙基甲基纤维素。 羟丙基甲基纤维素至少为8.3至9.8％羟基丙氧基化。 口服剂型中的米诺环素在1小时内具有约35％至约50％，2小时内约60％至约75％，4小时内至少约90％的释放速率。 还提供了治疗人类痤疮的方法和辅助医生处方剂量的米诺环素用于治疗痤疮的方法。

    METHOD FOR THE TREATMENT OF ACNE AND CERTAIN DOSAGE FORMS THEREOF
    3.
    发明申请
    METHOD FOR THE TREATMENT OF ACNE AND CERTAIN DOSAGE FORMS THEREOF 有权
    治疗ACNE及其某些剂型的方法

    公开(公告)号：US20100035846A1

    公开(公告)日：2010-02-11

    申请号：US12536359

    申请日：2009-08-05

    申请人： Mitchell Wortzman ,  R. Todd Plott ,  Steven B. Newhard ,  David Watt

    发明人： Mitchell Wortzman ,  R. Todd Plott ,  Steven B. Newhard ,  David Watt

    IPC分类号： A61K31/65

    CPC分类号： A61K31/65 ,  A61K9/2018 ,  A61K9/2054

    摘要： An oral dosage form, including 65 mg of minocycline, an amount of lactose monohydrate, and an amount of hydroxypropylmethylcellulose. The hydroxypropylmethylcellulose is hydroxypropylmethylcellulose that is about 8.9±0.2% hydroxypropoxylated. An oral dosage form, including 115 mg of minocycline, an amount of lactose monohydrate, and an amount of hydroxypropylmethylcellulose. The hydroxypropylmethylcellulose is hydroxypropylmethylcellulose that is about 8.9±0.2% hydroxypropoxylated.

    摘要翻译： 口服剂型，包括65mg米诺环素，一定量的乳糖一水合物和一定量的羟丙基甲基纤维素。 羟丙基甲基纤维素是约8.9±0.2％羟丙氧基化的羟丙基甲基纤维素。 口服剂型，包括115毫克米诺环素，一定量的乳糖一水合物和一定量的羟丙基甲基纤维素。 羟丙基甲基纤维素是约8.9±0.2％羟丙氧基化的羟丙基甲基纤维素。