公开(公告)号：US4053609A

公开(公告)日：1977-10-11

申请号：US711858

申请日：1976-08-05

申请人： Mitsutaka Kawazu ,  Mitsuyoshi Wagatsuma ,  Masahiko Seto ,  Toshikazu Miyagishima ,  Totaro Yamaguchi ,  Satoshi Ohshima

发明人： Mitsutaka Kawazu ,  Mitsuyoshi Wagatsuma ,  Masahiko Seto ,  Toshikazu Miyagishima ,  Totaro Yamaguchi ,  Satoshi Ohshima

IPC分类号： C07C271/22 ,  C07D207/46 ,  C07D499/00 ,  C07D499/68 ,  A61K31/43

CPC分类号： C07C271/22 ,  C07D207/46 ,  C07D499/00

摘要： A compound of the formula: ##STR1## wherein R.sup.1 is hydrogen or hydroxy, R.sup.2 is a group of the formula: --CO-CH(NH.sub.2)-CH.sub.2 COR.sup.3 or --COCH.sub.2 -CH(NH.sub.2)-COR.sup.3, and R.sup.3 is selected from the group consisting of hydroxy, lower alkylamino, di-lower alkylamino, lower alkoxy and hydroxy-lower alkylamino, or R.sup.3 is amino when R.sup.2 is hydroxy. Several methods of preparing the compound [I] are also disclosed. The compound [I] and a pharmaceutically acceptable salt thereof are useful as antimicrobial agents.

公开(公告)号：US3974274A

公开(公告)日：1976-08-10

申请号：US472377

申请日：1974-05-22

申请人： Hironori Kurita ,  Mitsutaka Kawazu ,  Kohki Takashima

发明人： Hironori Kurita ,  Mitsutaka Kawazu ,  Kohki Takashima

IPC分类号： C08B37/16 ,  C07H3/00

CPC分类号： C08B37/0012

摘要： A compound of the formula: ##SPC1##Wherein R.sup.2 is mesitylsulfonyl or 2,4,6-triisopropylbenzenesulfonyl and n is an integer of 6 or 7, is reacted with a compound of the formula:R.sup.3 --Hwherein R.sup.3 is amino, methyamino, dimethylamino or azido. When R.sup.3 is azido group, the product thus obtained is further subjected to catalytic hydrogenation. A cyclodextrin derivative of the formula: ##SPC2##Wherein R.sup.1 is amino, methylamino or dimethylamino and n is the same as defined above, is obtained. Said cyclodextrin derivative is useful as a hypolipemic agent.

摘要翻译： 下式的化合物：