公开(公告)号：US11851694B1

公开(公告)日：2023-12-26

申请号：US16794318

申请日：2020-02-19

Applicant: ModernaTX, Inc.

Inventor： David Mauger ,  Vladimir Presnyak ,  Amy E. Rabideau ,  Iain Mcfadyen

IPC: C12P19/34 ,  C12N15/11

CPC classification number: C12P19/34 ,  C12N15/11

Abstract: The present disclosure provides methods and compositions for high fidelity in vitro transcription reactions.

公开(公告)号：US20230250439A1

公开(公告)日：2023-08-10

申请号：US18093119

申请日：2023-01-04

Applicant: ModernaTX, Inc.

Inventor： David Mauger ,  Iain Mcfadyen ,  Vladimir Presnyak

IPC: C12N15/67 ,  A61K48/00

CPC classification number: C12N15/67 ,  A61K48/0066

Abstract: The disclosure relates to synthetic thermostable polynucleotides, as well as methods of synthesizing and delivering the polynucleotides.