-
公开(公告)号:US20110262949A1
公开(公告)日:2011-10-27
申请号:US12734226
申请日:2008-10-23
申请人: Mohammad R. Seyedsayamdost , Jianming Xie , Clement Tsz Chan , Lital Alfonta , Peter G. Schultz , Joanne Stubbe
发明人: Mohammad R. Seyedsayamdost , Jianming Xie , Clement Tsz Chan , Lital Alfonta , Peter G. Schultz , Joanne Stubbe
CPC分类号: C12N9/0093 , C12Q1/26 , G01N2333/9029
摘要: This invention provides reductase proteins that comprise NH2Y unnatural amino acid residues, systems of orthogonal elements for incorporating NH2Y into reductases and methods of using NH2Y amino acid residues in reductases as molecular probes for probing reductases function, structure and activity.
摘要翻译: 本发明提供了包含NH2Y非天然氨基酸残基的还原酶蛋白,用于将NH2Y并入还原酶的正交元件的系统和在还原酶中使用NH 2 Y氨基酸残基作为探针还原酶功能,结构和活性的分子探针的方法。
-
公开(公告)号:US08673591B2
公开(公告)日:2014-03-18
申请号:US12734226
申请日:2008-10-23
申请人: Mohammad R. Seyedsayamdost , Jianming Xie , Clement Tsz Chan , Lital Alfonta , Peter G. Schultz , Joanne Stubbe
发明人: Mohammad R. Seyedsayamdost , Jianming Xie , Clement Tsz Chan , Lital Alfonta , Peter G. Schultz , Joanne Stubbe
IPC分类号: C12N15/67 , C12P21/02 , C07K14/00 , C07K14/505
CPC分类号: C12N9/0093 , C12Q1/26 , G01N2333/9029
摘要: This invention provides reductase proteins that comprise NH2Y unnatural amino acid residues, systems of orthogonal elements for incorporating NH2Y into reductases and methods of using NH2Y amino acid residues in reductases as molecular probes for probing reductases function, structure and activity.
摘要翻译: 本发明提供了包含NH2Y非天然氨基酸残基的还原酶蛋白,用于将NH2Y并入还原酶的正交元件的系统和在还原酶中使用NH 2 Y氨基酸残基作为探针还原酶功能,结构和活性的分子探针的方法。
-
公开(公告)号:US20090208994A1
公开(公告)日:2009-08-20
申请号:US12257303
申请日:2008-10-23
申请人: Mohammad R. Seyedsayamdost , Jianming Xie , Tsz Yan Clement Chan , Lital Alfonta , Peter G. Schultz , Joanne Stubbe
发明人: Mohammad R. Seyedsayamdost , Jianming Xie , Tsz Yan Clement Chan , Lital Alfonta , Peter G. Schultz , Joanne Stubbe
CPC分类号: C12N9/0093 , C12Q1/26 , G01N2333/9029
摘要: This invention provides reductase proteins that comprise NH2Y unnatural amino acid residues, systems of orthogonal elements for incorporating NH2Y into reductases and methods of using NH2Y amino acid residues in reductases as molecular probes for probing reductases function, structure and activity.
摘要翻译: 本发明提供了包含NH2Y非天然氨基酸残基的还原酶蛋白,用于将NH2Y并入还原酶的正交元件的系统和在还原酶中使用NH 2 Y氨基酸残基作为探针还原酶功能,结构和活性的分子探针的方法。
-
-