公开(公告)号：US20210244825A1

公开(公告)日：2021-08-12

申请号：US17155773

申请日：2021-01-22

Applicant: Monash University

Inventor： Charles Reay MACKAY ,  Di YU ,  Remy ROBERT

IPC: A61K47/68 ,  C07K16/24 ,  A61K38/20

Abstract: The invention relates to IL-21, to antibodies and related fragments thereof for binding to IL-21, to production of said antibodies and fragments and to use of said antibodies and fragments for detection and therapy of various conditions, in particular inflammation, infection and oncology.

公开(公告)号：US20210002362A1

公开(公告)日：2021-01-07

申请号：US16937121

申请日：2020-07-23

Applicant: Monash University

Inventor： Charles Reay MACKAY ,  Di YU

IPC: C07K16/24 ,  A61K39/395 ,  A61K45/06

Abstract: The present disclosure provides proteins comprising antigen binding sites of antibodies that bind to interleukin-21 (IL-21) and uses thereof, e.g., in therapy.