公开(公告)号：US20210244825A1

公开(公告)日：2021-08-12

申请号：US17155773

申请日：2021-01-22

Applicant: Monash University

Inventor： Charles Reay MACKAY ,  Di YU ,  Remy ROBERT

IPC: A61K47/68 ,  C07K16/24 ,  A61K38/20

Abstract: The invention relates to IL-21, to antibodies and related fragments thereof for binding to IL-21, to production of said antibodies and fragments and to use of said antibodies and fragments for detection and therapy of various conditions, in particular inflammation, infection and oncology.

公开(公告)号：US20210002362A1

公开(公告)日：2021-01-07

申请号：US16937121

申请日：2020-07-23

Applicant: Monash University

Inventor： Charles Reay MACKAY ,  Di YU

IPC: C07K16/24 ,  A61K39/395 ,  A61K45/06

Abstract: The present disclosure provides proteins comprising antigen binding sites of antibodies that bind to interleukin-21 (IL-21) and uses thereof, e.g., in therapy.

公开(公告)号：US20240109971A1

公开(公告)日：2024-04-04

申请号：US18266445

申请日：2021-12-14

Applicant: MONASH UNIVERSITY

Inventor： Remy ROBERT ,  Charles Reay MACKAY

IPC: C07K16/28 ,  A61P17/06 ,  A61P37/06 ,  C07K14/715

CPC classification number: C07K16/2866 ,  A61P17/06 ,  A61P37/06 ,  C07K14/7158 ,  A61K2039/505 ,  C07K2317/569

Abstract: The invention relates to CCR6, to antibodies and related fragments thereof for binding to said receptors, to production of said antibodies and fragments and to use of said antibodies and fragments for detection and therapy of various conditions, in particular autoimmune diseases, inflammation, infection, oncology and fibrosis.