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公开(公告)号：US20050074850A1
公开(公告)日：2005-04-07
申请号：US10856122
申请日：2004-05-28
申请人： Monica Nadler , Jean-Pierre Kinet , Pierre Launay , Jerome Mahiou
发明人： Monica Nadler , Jean-Pierre Kinet , Pierre Launay , Jerome Mahiou
IPC分类号： C07K14/705 , C07H21/04
CPC分类号： C07K14/705
摘要： Differentially expressed L-type calcium channel nucleic acid sequences and polypeptides have been identified that include novel sequences that are differentially expressed in non-excitable cells. Such sequences can be used, for example, as targets for identifying agents that modulate calcium influx, e.g., in non-excitable cells. Methods related to modulation of cell growth are also included.
摘要翻译： 已经鉴定了差异表达的L型钙通道核酸序列和多肽，其包括在不可兴奋细胞中差异表达的新型序列。 这样的序列可以用于例如用于鉴定调节钙流入的试剂的靶标，例如在不可兴奋的细胞中。 还包括与细胞生长调节有关的方法。
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2.发明申请公开(公告)号：US20080085280A1
公开(公告)日：2008-04-10
申请号：US10591642
申请日：2005-03-04
申请人： Renato Monteiro , Benoit Pasquier , Ulrich Blank , Marc Benhamou , Pierre Launay , Marina Pretolani
发明人： Renato Monteiro , Benoit Pasquier , Ulrich Blank , Marc Benhamou , Pierre Launay , Marina Pretolani
IPC分类号： A61K39/395 , A61P1/00 , A61P13/12 , A61P19/02 , A61P7/12
CPC分类号： C07K16/283 , A61K2039/505 , C07K2317/54 , C07K2317/77 , Y10S424/804 , Y10S424/809
摘要： The invention relates to the use of a monovalent antibody fragment directed against the EC2 domain of the FcαRI receptor for the treatment of inflammatory diseases.
摘要翻译： 本发明涉及针对FcalphaRI受体的EC2结构域的单价抗体片段用于治疗炎性疾病的用途。
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公开(公告)号：US20190135898A1
公开(公告)日：2019-05-09
申请号：US16161931
申请日：2018-10-16
摘要： The present invention relates to a soluble peptide comprising the amino acids sequence: KRFYVVMWKK (SEQ ID NO:1) or a function-conservative variant thereof for use in the treatment of cancer.The invention also relates to a pharmaceutical composition for use in the treatment of cancer comprising at least one soluble peptide according to the invention or at least one acid nucleic according to the invention or at least one expression vector according to the invention, or at least one host cell according to the invention and a pharmaceutically acceptable carrier.
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公开(公告)号：US10759843B2
公开(公告)日：2020-09-01
申请号：US16161931
申请日：2018-10-16
摘要： The present invention relates to a soluble peptide comprising the amino acids sequence: KRFYVVMWKK (SEQ ID NO:1) or a function-conservative variant thereof for use in the treatment of cancer.The invention also relates to a pharmaceutical composition for use in the treatment of cancer comprising at least one soluble peptide according to the invention or at least one acid nucleic according to the invention or at least one expression vector according to the invention, or at least one host cell according to the invention and a pharmaceutically acceptable carrier.
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公开(公告)号：US07892538B2
公开(公告)日：2011-02-22
申请号：US10591642
申请日：2005-03-04
申请人： Renato Monteiro , Benoît Pasquier , Ulrich Blank , Marc Benhamou , Pierre Launay , Marina Pretolani
发明人： Renato Monteiro , Benoît Pasquier , Ulrich Blank , Marc Benhamou , Pierre Launay , Marina Pretolani
IPC分类号： A61K39/395
CPC分类号： C07K16/283 , A61K2039/505 , C07K2317/54 , C07K2317/77 , Y10S424/804 , Y10S424/809
摘要： The invention relates to the use of a monovalent antibody fragment directed against the EC2 domain of the FcαRI receptor for the treatment of inflammatory diseases.
摘要翻译： 本发明涉及针对FcαRI受体的EC2结构域的单价抗体片段用于治疗炎性疾病的用途。
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