公开(公告)号：US12241074B2

公开(公告)日：2025-03-04

申请号：US16472140

申请日：2017-12-21

Applicant: Monsanto Technology LLC

Inventor： Ty J. Barten ,  Edward J. Cargill ,  Jonathan C. Lamb ,  Bryce Lemke ,  Linda A. Rymarquis ,  Dennis H. Yang

IPC: C12N15/82 ,  A01H1/06 ,  A01H5/10 ,  A01H6/46 ,  C07K14/415

Abstract: Disclosed herein are plants exhibiting a semi-dwarf phenotype with reduced plant height compared to control wildtype plants. Some of the disclosed semi-dwarf plants comprise at least one non-natural brachytic mutation in which the activity of a BR2 gene is reduced. Also disclosed are methods for producing a semi-dwarf corn plant using a CRISPR based genome editing system.

公开(公告)号：US12024711B2

公开(公告)日：2024-07-02

申请号：US17613115

申请日：2020-05-28

Applicant: MONSANTO TECHNOLOGY LLC

Inventor： Sivalinganna Manjunath ,  Linda A. Rymarquis ,  Thomas L. Slewinski

IPC: C12N15/82 ,  C12N9/00 ,  C12N9/02

CPC classification number: C12N15/8218 ,  C12N9/0071 ,  C12N15/8213 ,  C12N15/8262 ,  C12Y114/11012

Abstract: The present disclosure provides compositions and methods for altering gibberellin (GA) content in corn or other cereal plants. Methods and compositions are also provided for altering the expression of genes related to gibberellin biosynthesis through editing of specific subtypes of GA20 oxidase genes to introduce an antisense sequence or segment into the gene. Modified plant cells and plants having a dominant allele reducing the expression or activity of one or more GA oxidase genes are further provided comprising reduced gibberellin levels and improved characteristics, such as reduced plant height and increased lodging resistance, but without off-types.