公开(公告)号：US06981958B1

公开(公告)日：2006-01-03

申请号：US10626181

申请日：2003-07-24

申请人： Morteza Gharib ,  Hosheng Tu ,  Olav Bergheim

发明人： Morteza Gharib ,  Hosheng Tu ,  Olav Bergheim

IPC分类号： A61M5/00 ,  A61M5/32

CPC分类号： A61F9/00781 ,  A61B3/16

摘要： A trabecular shunt and methods for treating glaucoma are disclosed. One of the methods comprises transporting fluid from the anterior chamber of an eye to Schlemm's canal through an implant, the implant extending between the anterior chamber and Schlemm's canal; sensing an intraocular pressure using a sensor incorporated into the implant; and transmitting a signal indicative of the sensed pressure to an external receiver.

摘要翻译： 公开了一种小梁分流术和治疗青光眼的方法。 其中一种方法包括通过植入物将流体从眼前房输送到施莱姆氏管，植入物在前房与施莱姆氏管之间延伸; 使用结合到植入物中的传感器感测眼内压; 以及将指示感测到的压力的信号发送到外部接收器。

公开(公告)号：US20050288619A1

公开(公告)日：2005-12-29

申请号：US11209563

申请日：2005-08-23

申请人： Morteza Gharib ,  Hosheng Tu ,  Olav Bergheim

发明人： Morteza Gharib ,  Hosheng Tu ,  Olav Bergheim

IPC分类号： A61F9/007 ,  A61M5/00 ,  A61F9/00

CPC分类号： A61F9/00781 ,  A61B3/16

摘要： A trabecular shunt and methods for treating glaucoma are disclosed. One of the methods comprises transporting fluid from the anterior chamber of an eye to Schlemm's canal through an implant, the implant extending between the anterior chamber and Schlemm's canal; sensing an intraocular pressure using a sensor incorporated into the implant; and transmitting a signal indicative of the sensed pressure to an external receiver.

摘要翻译： 公开了一种小梁分流术和治疗青光眼的方法。 其中一种方法包括通过植入物将流体从眼前房输送到施莱姆氏管，植入物在前房与施莱姆氏管之间延伸; 使用结合到植入物中的传感器感测眼内压; 以及将指示感测到的压力的信号发送到外部接收器。

公开(公告)号：US20050192527A1

公开(公告)日：2005-09-01

申请号：US11121584

申请日：2005-05-04

申请人： Morteza Gharib ,  Hosheng Tu ,  Olav Bergheim

发明人： Morteza Gharib ,  Hosheng Tu ,  Olav Bergheim

IPC分类号： A61F9/007 ,  A61M5/00

CPC分类号： A61F9/00781 ,  A61B3/16

摘要： A trabecular shunt and methods for treating glaucoma are disclosed. One of the methods comprises transporting fluid from the anterior chamber of an eye to Schlemm's canal through an implant, the implant extending between the anterior chamber and Schlemm's canal; sensing an intraocular pressure using a sensor incorporated into the implant; and transmitting a signal indicative of the sensed pressure to an external receiver.

摘要翻译： 公开了一种小梁分流术和治疗青光眼的方法。 其中一种方法包括通过植入物将流体从眼前房输送到施莱姆氏管，植入物在前房与施莱姆氏管之间延伸; 使用结合到植入物中的传感器感测眼内压; 以及将指示感测到的压力的信号发送到外部接收器。

公开(公告)号：US06666841B2

公开(公告)日：2003-12-23

申请号：US09847523

申请日：2001-05-02

申请人： Morteza Gharib ,  Hosheng Tu ,  Olav Bergheim

发明人： Morteza Gharib ,  Hosheng Tu ,  Olav Bergheim

IPC分类号： A61M500

CPC分类号： A61F9/00781

摘要： A trabecular shunt and methods for treating glaucoma are disclosed. The method comprises placing a trabecular shunt through diseased trabecular meshwork, between the anterior chamber and Schlemm's canal. The trabecular shunt includes a hollow, elongated tubular element having an inlet section and an outlet section. The outlet section includes two bifurcatable elements adapted to be positioned and stabilized inside Schlemm's canal.

公开(公告)号：US20090076436A2

公开(公告)日：2009-03-19

申请号：US11121584

申请日：2005-05-04

申请人： Morteza Gharib ,  Hosheng Tu ,  Olav Bergheim

发明人： Morteza Gharib ,  Hosheng Tu ,  Olav Bergheim

IPC分类号： A61M5/00

CPC分类号： A61F9/00781 ,  A61B3/16

摘要： An implant has a tubular member with an inlet configured to receive fluid from an anterior chamber of an eye, an outlet configured to deliver fluid from the inlet to a physiological outflow pathway of the eye, and a lumen therebetween configured for substantially free flow of the fluid and which generally defines a flow axis. At the outlet of the tubular member is a distal deployable portion that has a compacted position and an expanded position. The deployable portion is configured to expand in the physiological outflow pathway of the eye and moves transversely when transitioning between the compacted and expanded positions about a pivot axis which is substantially perpendicular to the flow axis.

摘要翻译： 植入物具有管状构件，入口被配置为从眼睛的前房接收流体，构造成将流体从入口输送到眼睛的生理流出路径的出口，以及其间的管腔，被构造成基本上自由地流动 流体并且其通常限定流动轴线。 在管状构件的出口处是具有压实位置和展开位置的远端展开部分。 可展开部分构造成在眼睛的生理流出路径中膨胀并且在围绕基本上垂直于流动轴线的枢转轴线在压实和扩张位置之间转换时横向移动。

公开(公告)号：US20070282244A1

公开(公告)日：2007-12-06

申请号：US11836109

申请日：2007-08-08

申请人： Hosheng Tu ,  Olav Bergheim ,  Morteza Gharib

发明人： Hosheng Tu ,  Olav Bergheim ,  Morteza Gharib

IPC分类号： A61M27/00

CPC分类号： A61F9/00781 ,  A61F9/0017 ,  A61F9/007 ,  A61F2009/00891 ,  A61F2250/0067 ,  A61K9/0051 ,  A61M27/002 ,  A61M2210/0612 ,  Y10S623/905

摘要： A glaucoma treatment device for directing the flow of aqueous humor and bypassing trabecular meshwork is shown. The device includes an inlet section, an outlet section, a middle section, and at least one lumen for transmitting aqueous humor within the glaucoma device. The lumen extends through at least one of the sections, and the outlet section is substantially perpendicular to the middle section and fits within a conduit of aqueous humor outflow in the eye.

摘要翻译： 示出了用于引导房水流动并绕过小梁网的青光眼治疗装置。 该装置包括入口部分，出口部分，中间部分和用于在青光眼装置内传送房水的至少一个内腔。 内腔延伸穿过至少一个部分，并且出口部分基本上垂直于中间部分并且配合在眼睛中的房水流出物的导管内。

公开(公告)号：US20080234624A2

公开(公告)日：2008-09-25

申请号：US10889254

申请日：2004-07-12

申请人： Olav Bergheim ,  Morteza Gharib

发明人： Olav Bergheim ,  Morteza Gharib

IPC分类号： A61F9/007

CPC分类号： A61F9/00781 ,  A61F9/0017 ,  A61F9/007 ,  A61F2009/00891 ,  A61F2250/0067 ,  A61K9/0051 ,  A61M27/002 ,  A61M2210/0612 ,  Y10S623/905

摘要： An ocular disorder treatment implant includes an anchor and a therapeutic agent. The implant has a body with first and second end portions. The implant is configured to transport fluid from the anterior chamber of an eye to a physiological outflow pathway of the eye. The body has at least one inlet opening at the first end portion and at least one outlet opening at the second end portion such that the inlet and outlet openings are in fluid communication and define an axis therebetween. The anchor extends substantially perpendicularly to a part of the axis between the openings, and at least one outlet opening is configured to be positioned in the physiological outflow pathway. One implant has two outlet openings, and the anchor is disposed closer to one of the outlet openings.

摘要翻译： 眼部疾病治疗植入物包括锚和治疗剂。 植入物具有带有第一和第二端部的主体。 植入物构造成将流体从眼睛的前房输送到眼睛的生理流出路径。 主体在第一端部处具有至少一个入口开口和在第二端部处的至少一个出口开口，使得入口和出口开口处于流体连通并且在其间限定轴线。 锚固件基本上垂直于开口之间的轴线的一部分延伸，并且至少一个出口开口构造成位于生理流出路径中。 一个植入物具有两个出口开口，并且锚定件被设置成更靠近一个出口开口。

公开(公告)号：US20060195056A1

公开(公告)日：2006-08-31

申请号：US11412454

申请日：2006-04-27

申请人： Olav Bergheim ,  Morteza Gharib

发明人： Olav Bergheim ,  Morteza Gharib

IPC分类号： A61M5/00

CPC分类号： A61F9/00781 ,  A61F9/0017 ,  A61F9/007 ,  A61F2009/00891 ,  A61F2250/0067 ,  A61K9/0051 ,  A61M27/002 ,  A61M2210/0612 ,  Y10S623/905

摘要： Surgical methods and related medical devices for treating glaucoma are disclosed. The method comprises trabecular bypass surgery, which involve bypassing diseased trabecular meshwork with the use of a seton implant. The seton implant is used to prevent a healing process known as filling in, which has a tendency to close surgically created openings in the trabecular meshwork. The surgical method and novel implant are addressed to the trabecular meshwork, which is a major site of resistance to outflow in glaucoma. In addition to bypassing the diseased trabecular meshwork at the level of the trabecular meshwork, existing outflow pathways are also used or restored. The seton implant is positioned through the trabecular meshwork so that an inlet end of the seton implant is exposed to the anterior chamber of the eye and an outlet end is positioned into fluid collection channels at about an exterior surface of the trabecular meshwork or up to the level of aqueous veins.

公开(公告)号：US20060084907A1

公开(公告)日：2006-04-20

申请号：US11294794

申请日：2005-12-06

申请人： Olav Bergheim ,  Morteza Gharib

发明人： Olav Bergheim ,  Morteza Gharib

IPC分类号： A61M5/00

CPC分类号： A61F9/00781 ,  A61F9/0017 ,  A61F9/007 ,  A61F2009/00891 ,  A61F2250/0067 ,  A61K9/0051 ,  A61M27/002 ,  A61M2210/0612 ,  Y10S623/905

摘要： Surgical methods and related medical devices for treating glaucoma are disclosed. The method comprises trabecular bypass surgery, which involve bypassing diseased trabecular meshwork with the use of a seton implant. The seton implant is used to prevent a healing process known as filling in, which has a tendency to close surgically created openings in the trabecular meshwork. The surgical method and novel implant are addressed to the trabecular meshwork, which is a major site of resistance to outflow in glaucoma. In addition to bypassing the diseased trabecular meshwork at the level of the trabecular meshwork, existing outflow pathways are also used or restored. The seton implant is positioned through the trabecular meshwork so that an inlet end of the seton implant is exposed to the anterior chamber of the eye and an outlet end is positioned into fluid collection channels at about an exterior surface of the trabecular meshwork or up to the level of aqueous veins.

摘要翻译： 公开了用于治疗青光眼的手术方法和相关的医疗装置。 该方法包括小梁旁路手术，其涉及利用植入物绕过患病的小梁网。 镶嵌植入物用于防止称为填充的愈合过程，其具有在小梁网中关闭手术产生的开口的趋势。 手术方法和新型植入物是针对小梁网，其是青光眼流出阻力的主要部位。 除了在小梁网的水平绕过患病的小梁网，还使用或恢复现有的流出路径。 镶嵌植入物定位成穿过小梁网，使得植入植入物的入口端暴露于眼睛的前房，并且出口端被定位在小梁网的大约外表面处的流体收集通道中，或直到 水静脉水平。

公开(公告)号：US20050209550A1

公开(公告)日：2005-09-22

申请号：US11124440

申请日：2005-05-06

申请人： Olav Bergheim ,  Morteza Gharib

发明人： Olav Bergheim ,  Morteza Gharib

IPC分类号： A61F9/007 ,  A61M5/00 ,  A61M27/00

CPC分类号： A61F9/00781 ,  A61F9/0017 ,  A61F9/007 ,  A61F2009/00891 ,  A61F2250/0067 ,  A61K9/0051 ,  A61M27/002 ,  A61M2210/0612 ,  Y10S623/905

摘要： Surgical methods and related medical devices for treating glaucoma are disclosed. The method comprises trabecular bypass surgery, which involve bypassing diseased trabecular meshwork with the use of a seton implant. The seton implant is used to prevent a healing process known as filling in, which has a tendency to close surgically created openings in the trabecular meshwork. The surgical method and novel implant are addressed to the trabecular meshwork, which is a major site of resistance to outflow in glaucoma. In addition to bypassing the diseased trabecular meshwork at the level of the trabecular meshwork, existing outflow pathways are also used or restored. The seton implant is positioned through the trabecular meshwork so that an inlet end of the seton implant is exposed to the anterior chamber of the eye and an outlet end is positioned into fluid collection channels at about an exterior surface of the trabecular meshwork or up to the level of aqueous veins.

摘要翻译： 公开了用于治疗青光眼的手术方法和相关的医疗装置。 该方法包括小梁旁路手术，其涉及利用植入物绕过患病的小梁网。 镶嵌植入物用于防止称为填充的愈合过程，其具有在小梁网中关闭手术产生的开口的趋势。 手术方法和新型植入物是针对小梁网，其是青光眼流出阻力的主要部位。 除了在小梁网的水平绕过患病的小梁网，还使用或恢复现有的流出路径。 镶嵌植入物定位成穿过小梁网，使得植入植入物的入口端暴露于眼睛的前房，并且出口端被定位在小梁网的大约外表面处的流体收集通道中，或直到 水静脉水平。