专利检索 ap:("Mustapha Abarghaz" OR "Stefano Biondi" OR "Jérôme Duranton") AND inv:"Jérôme Duranton" 第 1 页

1.

发明申请
Compounds, preparation and therapeutic use thereof 审中-公开
标题翻译：化合物，其制备和治疗用途

公开(公告)号：US20090215752A1

公开(公告)日：2009-08-27

申请号：US11989269

申请日：2006-08-02

申请人： Mustapha Abarghaz , Stefano Biondi , Jérôme Duranton

发明人： Mustapha Abarghaz , Stefano Biondi , Jérôme Duranton

IPC分类号： A61K31/5513 , C07D243/14 , A61P25/00

CPC分类号： C07D243/24 , C07D401/04

摘要： The invention relates to benzodiazepine derivatives having PDE2 inhibitory activities, as well as therapeutic methods of administering said compounds, in particular for treating various diseases of the central or peripheral nervous system. The invention further includes methods of preparing the subject compounds and pharmaceutical compositions containing them.

摘要翻译： 本发明涉及具有PDE2抑制活性的苯并二氮杂衍生物，以及施用所述化合物，特别是用于治疗中枢或周围神经系统的各种疾病的治疗方法。本发明还包括制备本发明化合物的方法和含有它们的药物组合物。

2.

发明授权
Benzo-1,4-diazepin-2-one derivatives as phosphodiesterase PDE2 inhibitors, preparation and therapeutic use thereof 失效
标题翻译：苯并-1,4-二氮杂-2-酮衍生物作为磷酸二酯酶PDE2抑制剂，其制备和治疗用途

公开(公告)号：US07410963B2

公开(公告)日：2008-08-12

申请号：US10582131

申请日：2004-12-23

申请人： Mustapha Abarghaz , Stefano Biondi , Jérôme Duranton , Emmanuelle Limanton , Cesare Mondadori , Patrick Wagner

发明人： Mustapha Abarghaz , Stefano Biondi , Jérôme Duranton , Emmanuelle Limanton , Cesare Mondadori , Patrick Wagner

IPC分类号： C07D243/24 , C07D413/04 , A61K31/5513

CPC分类号： C07D405/04 , C07D243/24

摘要： The invention relates to compounds having PDE2 inhibitory activities, as well as therapeutic methods by administering said compounds, in particular for treating various diseases of the central or peripheral nervous system. It further deals with pharmaceutical compositions comprising said compounds and methods for preparing said compounds.

摘要翻译： 本发明涉及具有PDE2抑制活性的化合物，以及通过施用所述化合物，特别是用于治疗中枢或周围神经系统的各种疾病的治疗方法。它还涉及包含所述化合物的药物组合物和制备所述化合物的方法。