公开(公告)号：US20220395795A1

公开(公告)日：2022-12-15

申请号：US17628754

申请日：2021-01-15

申请人： NANTONG UNIVERSITY

发明人： Xin TANG ,  Cheng SUN ,  Xiaokun GU ,  Xiaosong GU ,  Qianru HE ,  Tianmei QIAN ,  Wenfeng SU ,  Haoming LI

IPC分类号： B01J13/02 ,  C07K1/14 ,  C12N5/079

摘要： Ag-Fe3O4 immunomagnetic microsphere contains poly-D-lysine modified on the surface and S100β and/or MBP antibody linked by an amide bond. The Ag-Fe3O4 immunomagnetic microsphere can specifically capturing peripheral nerve tissue-derived exosomes. When the microsphere is used to extract nerve tissue-derived exosomes, the extraction yield of exosomes per unit volume of nerve tissue is high, and the nerve specificity is strong.