公开(公告)号：US20150017658A1

公开(公告)日：2015-01-15

申请号：US14499364

申请日：2014-09-29

Applicant: NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY

Inventor： GREGORY ALAN COOKSEY ,  JOHN T. ELLIOTT ,  ANNE L. PLANT

IPC: G01N33/569 ,  G01N33/533 ,  G01N33/535

CPC classification number: G01N33/56966 ,  G01N33/533 ,  G01N2496/00

Abstract: A kit includes a reference probe to react with a first sample; and an analyte probe to combine with a second sample, a marker and a spectral probe to react to form the analyte probe to combine with the second sample, the marker to react with the reference probe to form the analyte probe to combine with the second sample, or a combination thereof. A process for staining includes forming a reference composition by reacting a reference probe and a first sample to form a reference; and forming an analyte composition by combining an analyte probe and a second sample to form an analyte.

Abstract translation: 试剂盒包括与第一样品反应的参考探针; 以及分析物探针，其与第二样品，标记物和光谱探针结合以反应以形成分析物探针以与第二样品组合，所述标记物与参考探针反应以形成分析物探针以与第二样品组合 ，或其组合。 染色方法包括通过使参考探针和第一样品反应形成参考物来形成参考组合物; 以及通过组合分析物探针和第二样品以形成分析物形成分析物组合物。

公开(公告)号：US20150168300A1

公开(公告)日：2015-06-18

申请号：US14607290

申请日：2015-01-28

Applicant: NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY

Inventor： ALEXANDER W. PETERSON ,  ANNE L. PLANT ,  MICHAEL HALTER

IPC: G01N21/552

CPC classification number: G01N21/553 ,  G02B21/0076 ,  G02B21/361

Abstract: An article to perform surface plasmon resonance imaging includes a light source to provide source light, the source light including a source optical profile, the source optical profile being selected to match a transmission profile at a surface plasmon resonance angle; an optical transformer configured to: receive the source light from the light source; and produce a transformed light comprising the source optical profile; and an optical modifier including: a back focal plane disposed at a first surface of the optical modifier and including the transmission profile; and an image focal plane disposed at a second surface of the optical modifier opposing the back focal plane, the optical modifier being configured to: magnify the transformed light; and produce magnified transformed light that includes the source optical profile.

Abstract translation: 执行表面等离子体共振成像的物品包括提供源光的光源，源光包括源光学轮廓，源光学轮廓被选择以匹配表面等离子体共振角的透射轮廓; 光变换器，被配置为：从所述光源接收源光; 并产生包括源光学轮廓的变换光; 以及光学修正器，包括：后焦平面，设置在所述光学修饰器的第一表面并且包括所述透射轮廓; 以及设置在所述光学修饰器的与所述后焦平面相对的第二表面处的图像焦平面，所述光学修改器被配置为：放大所述经变换的光; 并产生包括源光学轮廓的放大变换光。