公开(公告)号：US20220404363A1

公开(公告)日：2022-12-22

申请号：US17774395

申请日：2020-11-02

Applicant: NEC CORPORATION ,  UNIVERSITY OF THE RYUKYUS

Inventor： Yoshiko YOSHIHARA ,  Takuya FUKUSHIMA ,  Yuetsu TANAKA ,  Hiroaki MASUZAKI ,  Kennosuke KARUBE ,  Naoki IMAIZUMI

IPC: G01N33/569 ,  G01N33/68

Abstract: As a technique enabling to simply and accurately diagnose human T cell leukemia virus type 1 (HTLV-1) related disease, there is provided a diagnostic method for an HTLV-1 related disease based on an amount of tumor necrosis factor receptor 2 (TNFR2) in a blood sample taken from a subject, wherein (1) it is determined based on an increase of the amount of TNFR2 that the subject suffers from, or is likely to develop, the HTLV-1 related disease; and/or (2) it is determined based on a decrease of the amount of TNFR2 that the subject is in remission, or is likely to be in remission, of the HTLV-1 related disease.

公开(公告)号：US20220137050A1

公开(公告)日：2022-05-05

申请号：US17429206

申请日：2020-02-06

Applicant: NEC CORPORATION

Inventor： Yoshiko YOSHIHARA ,  Takuya FUKUSHIMA ,  Megumi MIYARA

IPC: G01N33/569

Abstract: As a technique enabling to simply and accurately diagnose human T cell leukemia virus type 1 (HTLV-1) related disease, there is provided a diagnostic method for an HTLV-1 related disease, comprising the steps of: measuring the amount of a marker protein in a blood sample taken from a subject, wherein the marker protein is at least one selected from the proteins listed in Tables 1 and 2; and, if a measured value is a predetermined reference value or more or the predetermined reference value or less, determining that the subject suffers from the HTLV-1 related disease or determining that the subject is in remission of the HTLV-1 related disease.