公开(公告)号：US20150153353A1

公开(公告)日：2015-06-04

申请号：US14405325

申请日：2013-06-04

Applicant: NESTEC SA

Inventor： Qinghong Li ,  Dorothy P. Laflamme ,  Steven S. Hannah

IPC: G01N33/68 ,  G01N33/92

CPC classification number: G01N33/6812 ,  G01N33/50 ,  G01N33/92 ,  G01N2570/00 ,  G01N2800/326 ,  Y10T436/142222 ,  Y10T436/143333 ,  Y10T436/163333 ,  Y10T436/201666

Abstract: The invention provides methods for diagnosing chronic valvular disease in an animal. The methods comprise obtaining a sample from the animal; analyzing the sample for the presence of one or more metabolites associated with chronic valvular disease; comparing the amount of each such metabolite identified in the sample to a corresponding amount of the same metabolite present in a sample from one or more comparable control animals that do not suffer from chronic valvular disease; and using said comparison to diagnose chronic valvular disease in the animal if the metabolites found in the animal's sample is greater than or less than the amount present in the control animal's sample.

Abstract translation: 本发明提供用于诊断动物中慢性瓣膜疾病的方法。 所述方法包括从动物获得样品; 分析样品中存在与慢性瓣膜疾病相关的一种或多种代谢物; 将样品中鉴定的每种这样的代谢物的量与来自不患有慢性瓣膜疾病的一种或多种可比对照动物的样品中存在的相同代谢物的相应量相比较; 并且如果动物样品中发现的代谢物大于或小于对照动物样品中存在的量，则使用所述比较来诊断动物中的慢性瓣膜病。