Method and apparatus for mitigating the effect of magnetization transfer in model-based magnetic resonance techniques

    公开(公告)号:US10725132B2

    公开(公告)日:2020-07-28

    申请号:US15822474

    申请日:2017-11-27

    IPC分类号: G01R33/48 G01R33/56 G01R33/50

    摘要: In a magnetic resonance (MR) apparatus, and model-based method, for identifying a nuclear spin-dependent attribute of a subject, MR signals are acquired in multiple repetitions of an MR data acquisition sequence that is changed from repetition-to-repetition so as to deliberately encode effects of magnetization transfer between nuclear spins into the acquired MR signals. A model is generated, composed of at least two molecule pools, in which a single magnetization transfer parameter is used that is derived from the MR signals in which the magnetization transfer is encoded. A nuclear spin-dependent attribute of the subject is then identified, by comparing at least one MR signal evolution from the subject to at least one signal evolution produced by the model.