公开(公告)号：US20210295508A1

公开(公告)日：2021-09-23

申请号：US17265367

申请日：2019-04-15

申请人： NIDEK CO., LTD.

发明人： Ryosuke SHIBA ,  Sohei MIYAZAKI ,  Yusuke SAKASHITA ,  Yoshiki KUMAGAI ,  Naoki TAKENO

IPC分类号： G06T7/00 ,  G06T5/50 ,  A61B3/10

摘要： In this invention, a control unit in an ophthalmic image processing device acquires an ophthalmic image captured by an ophthalmic image capture device (S11). The control unit, by inputting the ophthalmic image into a mathematical model that has been trained by a machine-learning algorithm, acquires a probability distribution in which the random variables are the coordinates at which a specific site and/or a specific boundary of a tissue is present within a region of the ophthalmic image (S14). On the basis of the acquired probability distribution, the control unit detects the specific boundary and/or the specific site (S16, S24).

公开(公告)号：US20150327763A1

公开(公告)日：2015-11-19

申请号：US14714988

申请日：2015-05-18

申请人： NIDEK CO., LTD.

发明人： Kazunari SHIMIZU ,  Kenji NAKAMURA ,  Yusuke SAKASHITA

IPC分类号： A61B3/10 ,  A61B3/14 ,  A61B3/15

CPC分类号： A61B3/14 ,  A61B3/1005 ,  A61B3/145 ,  A61B3/152

摘要： A corneal endothelial cell photographing apparatus for photographing endothelial cells of a patient eye's cornea, includes: a cornea photographing optical system including an imaging device and configured to project light toward the cornea and photograph the corneal endothelial cells through the imaging device; a light projecting optical system to project detection light in a first oblique direction to the cornea to detect a focus state of the cornea photographing optical system relative to the cornea; a detecting optical system including a detector with arranged pixels and configured to receive, in a second oblique direction opposite to the first oblique direction, corneal reflection light resulting from the detection light and including reflection light from the corneal endothelium through the detector, and detect an intensity distribution of the corneal reflection light in a depth direction; and a controller to cause a monitor to display the intensity distribution output from the detector.

摘要翻译： 一种用于拍摄患者眼睛角膜内皮细胞的角膜内皮细胞摄影装置，包括：角膜摄影光学系统，其包括成像装置并且被配置为将光投射到角膜并通过成像装置拍摄角膜内皮细胞; 投影光学系统，用于将第一倾斜方向的检测光投影到角膜，以检测角膜摄影光学系统相对于角膜的聚焦状态; 一种检测光学系统，包括具有排列像素的检测器，并且被配置为在与第一倾斜方向相反的第二倾斜方向上接收由检测光产生的角膜反射光，并且包括来自角膜内皮的反射光通过检测器，并且检测 角膜反射光在深度方向的强度分布; 以及使监视器显示从检测器输出的强度分布的控制器。

公开(公告)号：US20140016094A1

公开(公告)日：2014-01-16

申请号：US13940431

申请日：2013-07-12

申请人： NIDEK CO., LTD.

发明人： Yusuke SAKASHITA

IPC分类号： A61B3/00

CPC分类号： A61B3/0058 ,  A61B3/14

摘要： A corneal endothelial cell photographing apparatus for photographing an endothelial cell in the cornea of the examinee's eye includes an optical system, an image processor, and a display controller. The optical system includes an illuminating optical system for irradiating the cornea with illuminating light, and a light receiving optical system including a light detector and configured to receive reflected light from the cornea including the endothelial cell. The image processor analyzes each of endothelial cell images photographed at different positions on the cornea, and acquires an integrated analysis result by integrating the result of analysis of each of the endothelial cell images. The display controller displays the endothelial cell images simultaneously on a monitor with reference to an endothelial cell image photographed at a central portion of the cornea, and displays the integrated analysis result on the same screen as for the endothelial cell images.

摘要翻译： 用于拍摄受检者眼角膜内皮细胞的角膜内皮细胞摄影装置包括光学系统，图像处理器和显示控制器。 该光学系统包括用照射光照射角膜的照明光学系统和包括光检测器的光接收光学系统，并且被配置为接收来自包括内皮细胞的角膜的反射光。 图像处理器分析在角膜不同位置拍摄的每个内皮细胞图像，并通过整合每个内皮细胞图像的分析结果来获得综合分析结果。 显示控制器参照在角膜中心部分拍摄的内皮细胞图像在监视器上同时显示内皮细胞图像，并将整合分析结果显示在与内皮细胞图像相同的屏幕上。

公开(公告)号：US20130286350A1

公开(公告)日：2013-10-31

申请号：US13853681

申请日：2013-03-29

申请人： NIDEK CO., LTD.

发明人： Yusuke SAKASHITA ,  Naoto HONDA

IPC分类号： A61B3/14 ,  A61B3/15

CPC分类号： A61B3/14 ,  A61B3/0091 ,  A61B3/152

摘要： A corneal endothelial cell photographing apparatus includes: a main unit that includes an illumination optical system, an imaging optical system, and a fixation optical system; a setting unit configured to preliminarily set illumination positions and an illumination order of the plurality of fixation lamps; a controller configured to obtain an endothelial image at a first fixation position, control the fixation optical system corresponding to a determination result for propriety of the endothelial image obtained at the first fixation position to light a fixation lamp corresponding to a second fixation position preliminarily set by the setting unit, and control the illumination optical system and the imaging optical system to obtain an endothelial image at the second fixation position; a monitor configured to display the endothelial image; and an operating unit configured to input a signal for operating at least the controller.

摘要翻译： 角膜内皮细胞摄影装置包括：主体，包括照明光学系统，成像光学系统和固定光学系统; 设置单元，其被配置为预先设置所述多个固定灯的照明位置和照明顺序; 控制器，被配置为在第一固定位置获得内皮图像，控制所述固定光学系统对应于在所述第一固定位置处获得的内皮图像的适当性的确定结果，以点亮对应于由第一固定位置预先设置的第二固定位置的固定灯 设置单元，并控制照明光学系统和成像光学系统，以在第二固定位置获得内皮图像; 监视器，被配置为显示所述内皮图像; 以及操作单元，被配置为输入用于至少操作所述控制器的信号。

公开(公告)号：US20220358640A1

公开(公告)日：2022-11-10

申请号：US17621301

申请日：2020-07-29

申请人： NIDEK CO., LTD.

发明人： Yusuke SAKASHITA

IPC分类号： G06T7/00 ,  G06T11/00 ,  G06V10/764 ,  G16H30/40 ,  A61B3/00

摘要： A controller of a medical image processing device acquires a medical image of a subject. The controller causes a display to display a pre-modification image in which at least the position or range of a lesion to be modified on the medical image is displayed. The controller receives an instruction to designate at least the position or range of the lesion to be modified in a state in which the pre-modification image is displayed on the display. When at least the position or range of the lesion is designated, the controller acquires a predicted disease image in which the lesion is modified according to the designated information on the basis of the medical image. The controller causes the display to display the predicted disease image and the pre-modification image simultaneously or in a switching manner.

公开(公告)号：US20150327758A1

公开(公告)日：2015-11-19

申请号：US14715215

申请日：2015-05-18

申请人： NIDEK CO., LTD.

发明人： Yusuke SAKASHITA

IPC分类号： A61B3/00 ,  A61B3/13

CPC分类号： A61B3/0033 ,  A61B3/0025 ,  A61B3/0058

摘要： A corneal endothelial cell analysis method includes: a step of displaying a photographed image including endothelial cells of a cornea of an examinee's eye on a monitor; a step of setting, based on an operation signal from a user interface, regions of the endothelial cells for each or more than one of the cells with respect to the photographed image displayed on the monitor, the setting step including setting the endothelial cell regions on the one photographed image by use of setting modes including at least a first setting mode of setting the endothelial cell regions and a second setting mode different from the first setting mode; and a step of obtaining an analysis result on the endothelial cells of the examinee's eye based on the endothelial cell regions set by the first setting mode and the endothelial cell regions set by the second setting mode.

摘要翻译： 角膜内皮细胞分析方法包括：在监视器上显示包括受检者眼角膜的内皮细胞的拍摄图像的步骤; 基于来自用户界面的操作信号，针对显示在监视器上的拍摄图像，针对每个或多于一个单元格设置内皮细胞的区域的步骤，包括设置内皮细胞区域的设置步骤 使用至少包括设定内皮细胞区域的第一设定模式和与第一设定模式不同的第二设定模式的设定模式进行拍摄的图像; 以及基于由第一设定模式设定的内皮细胞区域和通过第二设定模式设定的内皮细胞区域，对被检眼的内皮细胞获得分析结果的步骤。