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公开(公告)号：US20230390425A1
公开(公告)日：2023-12-07
申请号：US18249220
申请日：2021-10-15
发明人： Minoru KAWATANI , Takahisa HANADA , Gota TONOYA , Takuya TAKEDA
IPC分类号： A61K51/10 , A61K33/244 , C07K16/32 , C07K7/08 , A61P35/00
CPC分类号： A61K51/1096 , A61K33/244 , C07K16/32 , C07K7/08 , A61P35/00 , A61K38/00
摘要： A conjugate of an anti-HER2 antibody site-specifically modified with a peptide and a chelating agent. The chelating agent is chelated with a metal radionuclide, the peptide and the chelating agent are linked by a linker (L), and the linker (L) does not contain a thiourea bond. A radiopharmaceutical including the conjugate as an active ingredient.
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公开(公告)号：US20240207464A1
公开(公告)日：2024-06-27
申请号：US18556527
申请日：2022-04-20
CPC分类号： A61K51/1096 , A61K51/1027 , A61P35/00
摘要： A conjugate of an anti-CD20 antibody and a chelating agent. The chelating agent is chelated with a metal radionuclide, the anti-CD20 antibody and the chelating agent are linked by a linker (L), and the linker (L) does not contain a thiourea bond. A radiopharmaceutical containing the conjugate as an active ingredient.
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公开(公告)号：US20240207463A1
公开(公告)日：2024-06-27
申请号：US18553443
申请日：2022-03-31
发明人： Minoru KAWATANI , Takahisa HANADA , Gota TONOYA , Takuya TAKEDA
CPC分类号： A61K51/1096 , A61P35/00
摘要： A conjugate of an anti-epidermal growth factor receptor (EGFR) antibody site-specifically modified with a peptide and a chelating agent. The chelating agent is chelated with a metal radionuclide, the peptide and the chelating agent are linked by a linker (L), and the linker (L) does not contain a thiourea bond.
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