公开(公告)号：US20160032354A1

公开(公告)日：2016-02-04

申请号：US14768331

申请日：2014-02-18

Applicant: NIPRO CORPORATION

Inventor： Kenta Tatsumi ,  Daisuke Nakamura

IPC: C12Q1/44

CPC classification number: C12Q1/44 ,  C07K2319/21 ,  C12N9/16 ,  G01N2333/916 ,  G01N2800/347

Abstract: It is an object of this invention to provide a simple measurement method capable of detecting indoxyl sulfuric acid in a sample rapidly and at high sensitivity. By causing sulfatase and tetrazolium salt to act on indoxyl sulfuric acid in a sample to generate a formazan dye, and then calculating the generation amount of the formazan dye, indoxyl sulfuric acid in the sample can be measured more simply, more rapidly, and at higher sensitivity as compared with former methods.

Abstract translation: 本发明的目的是提供一种能够快速且高灵敏度地检测样品中的吲哚硫酸的简单测量方法。 通过使硫酸酯酶和四唑鎓盐作用于样品中的吲哚硫酸以产生甲an染料，然后计算甲an染料的产生量，样品中的茚满硫酸可以更简单，更快速，更高 灵敏度与以前的方法相比。

公开(公告)号：US10150983B2

公开(公告)日：2018-12-11

申请号：US14768331

申请日：2014-02-18

Applicant: Nipro Corporation

Inventor： Kenta Tatsumi ,  Daisuke Nakamura

IPC: C12Q1/44 ,  C12N9/16

Abstract: It is an object of this invention to provide a simple measurement method capable of detecting indoxyl sulfuric acid in a sample rapidly and at high sensitivity. By causing sulfatase and tetrazolium salt to act on indoxyl sulfuric acid in a sample to generate a formazan dye, and then calculating the generation amount of the formazan dye, indoxyl sulfuric acid in the sample can be measured more simply, more rapidly, and at higher sensitivity as compared with former methods.