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公开(公告)号：US20170173156A1
公开(公告)日：2017-06-22
申请号：US15454132
申请日：2017-03-09
申请人： NORGINE BV
发明人： Lucy Clayton , Alasdair Cockett , Mark Christodoulou , Ian Davidson , Lynn Farrag , Marc Halphen , Leighton Jones , Vanik Petrossian , Peter Stein , David Tisi , Alex Ungar , Jeffrey Worthington
IPC分类号： A61K47/18 , A61K31/77 , A61K33/04 , A61K9/00 , A61K9/08 , A61K47/26 , A61K31/375 , A61K33/14
CPC分类号： A61K47/26 , A61K9/0053 , A61K9/0095 , A61K9/08 , A61K31/047 , A61K31/375 , A61K31/765 , A61K31/77 , A61K33/04 , A61K33/14 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/183 , Y10S514/892 , A61K2300/00
摘要： The invention provides a colon cleansing solution comprising:a) 300 to 800 mmol per litre ascorbate anion provided by a mixture of: (i) ascorbic acid and (ii) one or more salts of ascorbic acid the components (i) and (ii) being present in a molar ratio of from 1:4.5 to 1:7.0; and b) 10 to 200 g per litre polyethylene glycol. The invention also provides methods and kits associated with, or making use of the solutions, and compositions for the preparation of the solutions.
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公开(公告)号：US20170258919A1
公开(公告)日：2017-09-14
申请号：US15605617
申请日：2017-05-25
申请人： NORGINE BV
发明人： Lucy Clayton , Alasdair Cockett , Mark Christodoulou , Ian Davidson , Lynn Farrag , Marc Halphen , Leighton Jones , Vanik Petrossian , Peter Stein , David Tisi , Alex Ungar , Jeffrey Worthington
IPC分类号： A61K47/26 , A61K47/12 , A61K31/375 , A61K9/08 , A61K47/18 , A61K33/04 , A61K33/14 , A61K31/765 , A61K47/02 , A61K9/00 , A61K31/047
CPC分类号： A61K47/26 , A61K9/0053 , A61K9/0095 , A61K9/08 , A61K31/047 , A61K31/375 , A61K31/765 , A61K31/77 , A61K33/04 , A61K33/14 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/183 , Y10S514/892 , A61K2300/00
摘要： The invention provides a colon cleansing solution comprising: a) 300 to 800 mmol per litre ascorbate anion provided by a mixture of: (i) ascorbic acid and (ii) one or more salts of ascorbic acid the components (i) and (ii) being present in a molar ratio of from 1:4.5 to 1:7.0; and b) 10 to 200 g per litre polyethylene glycol. The invention also provides methods an kits associated with, or making use of the solutions, and compositions for the preparation of the solutions.
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公开(公告)号：US09326969B2
公开(公告)日：2016-05-03
申请号：US14657495
申请日：2015-03-13
申请人： NORGINE BV
发明人： Lucy Clayton , Alasdair Cockett , Mark Christodoulou , Ian Davidson , Lynn Farrag , Marc Halphen , Leighton Jones , Vanik Petrossian , Peter Stein , David Tisi , Alex Ungar , Jeffrey Worthington
IPC分类号： A61K31/375 , A61K31/765 , A61K47/02 , A61K47/26 , A61K9/00 , A61K31/047 , A61K33/04 , A61K33/14 , A61K47/18
CPC分类号： A61K47/26 , A61K9/0053 , A61K9/0095 , A61K9/08 , A61K31/047 , A61K31/375 , A61K31/765 , A61K31/77 , A61K33/04 , A61K33/14 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/183 , Y10S514/892 , A61K2300/00
摘要： The invention provides a colon cleansing solution comprising: a) 300 to 800 mmol per litre ascorbate anion provided by a mixture of: (i) ascorbic acid and (ii) one or more salts of ascorbic acid the components (i) and (ii) being present in a molar ratio of from 1:4.5 to 1:7.0; and b) 10 to 200 g per litre polyethylene glycol. The invention also provides methods and kits associated with, or making use of the solutions, and compositions for the preparation of the solutions.
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公开(公告)号：US20180311361A1
公开(公告)日：2018-11-01
申请号：US16028819
申请日：2018-07-06
申请人： NORGINE BV
发明人： Lucy Clayton , Alasdair Cockett , Mark Christodoulou , Ian Davidson , Lynn Farrag , Marc Halphen , Leighton Jones , Vanik Petrossian , Peter Stein , David Tisi , Alex Ungar , Jeffrey Worthington
IPC分类号： A61K47/26 , A61K33/04 , A61K47/02 , A61K31/77 , A61K31/375 , A61K47/10 , A61K9/08 , A61K47/12 , A61K9/00 , A61K31/047 , A61K33/14 , A61K47/18 , A61K31/765
CPC分类号： A61K47/26 , A61K9/0053 , A61K9/0095 , A61K9/08 , A61K31/047 , A61K31/375 , A61K31/765 , A61K31/77 , A61K33/04 , A61K33/14 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/183 , Y10S514/892 , A61K2300/00
摘要： The invention provides a colon cleansing solution comprising: a) 300 to 800 mmol per litre ascorbate anion provided by a mixture of: (i) ascorbic acid and (ii) one or more salts of ascorbic acid the components (i) and (ii) being present in a molar ratio of from 1:4.5 to 1:7.0; and b) 10 to 200 g per litre polyethylene glycol. The invention also provides methods and kits associated with, or making use of the solutions, and compositions for the preparation of the solutions.
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公开(公告)号：US09707297B2
公开(公告)日：2017-07-18
申请号：US15141054
申请日：2016-04-28
申请人： NORGINE BV
发明人： Lucy Clayton , Alasdair Cockett , Mark Christodoulou , Ian Davidson , Lynn Farrag , Marc Halphen , Leighton Jones , Vanik Petrossian , Peter Stein , David Tisi , Alex Ungar , Jeffrey Worthington
IPC分类号： A61K31/375 , A61K31/765 , A61K47/02 , A61K47/26 , A61K9/00 , A61K31/047 , A61K33/04 , A61K33/14 , A61K47/18 , A61K9/08 , A61K47/12
CPC分类号： A61K47/26 , A61K9/0053 , A61K9/0095 , A61K9/08 , A61K31/047 , A61K31/375 , A61K31/765 , A61K31/77 , A61K33/04 , A61K33/14 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/183 , Y10S514/892 , A61K2300/00
摘要： The invention provides a colon cleansing solution comprising: a) 300 to 800 mmol per liter ascorbate anion provided by a mixture of: (i) ascorbic acid and (ii) one or more salts of ascorbic acid the components (i) and (ii) being present in a molar ratio of from 1:4.5 to 1:7.0; and b) 10 to 200 g per liter polyethylene glycol. The invention also provides methods and kits associated with, or making use of the solutions, and compositions for the preparation of the solutions.
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公开(公告)号：US20160235854A1
公开(公告)日：2016-08-18
申请号：US15141054
申请日：2016-04-28
申请人： NORGINE BV
发明人： Lucy Clayton , Alasdair Cockett , Mark Christodoulou , Ian Davidson , Lynn Farrag , Marc Halphen , Leighton Jones , Vanik Petrossian , Peter Stein , David Tisi , Alex Ungar , Jeffrey Worthington
IPC分类号： A61K47/26 , A61K33/04 , A61K9/08 , A61K47/12 , A61K9/00 , A61K31/375 , A61K31/765 , A61K47/02
CPC分类号： A61K47/26 , A61K9/0053 , A61K9/0095 , A61K9/08 , A61K31/047 , A61K31/375 , A61K31/765 , A61K31/77 , A61K33/04 , A61K33/14 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/183 , Y10S514/892 , A61K2300/00
摘要： The invention provides a colon cleansing solution comprising: a) 300 to 800 mmol per litre ascorbate anion provided by a mixture of: (i) ascorbic acid and (ii) one or more salts of ascorbic acid the components (i) and (ii) being present in a molar ratio of from 1:4.5 to 1:7.0; and b) 10 to 200 g per litre polyethylene glycol. The invention also provides methods and kits associated with, or making use of the solutions, and compositions for the preparation of the solutions.
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公开(公告)号：US12083179B2
公开(公告)日：2024-09-10
申请号：US17384227
申请日：2021-07-23
申请人： NORGINE BV
发明人： Lucy Clayton , Alasdair Cockett , Mark Christodoulou , Ian Davidson , Lynn Farrag , Marc Halphen , Leighton Jones , Vanik Petrossian , Peter Stein , David Tisi , Alex Ungar , Jeffrey Worthington
IPC分类号： A61K47/26 , A61K9/00 , A61K9/08 , A61K31/047 , A61K31/375 , A61K31/765 , A61K31/77 , A61K33/04 , A61K33/14 , A61K47/02 , A61K47/10 , A61K47/12
CPC分类号： A61K47/26 , A61K9/0053 , A61K9/0095 , A61K9/08 , A61K31/047 , A61K31/375 , A61K31/765 , A61K31/77 , A61K33/04 , A61K33/14 , A61K47/02 , A61K47/10 , A61K47/12 , A61K31/375 , A61K2300/00 , A61K31/765 , A61K2300/00 , A61K31/77 , A61K2300/00
摘要： The invention provides a colon cleansing solution comprising:
a) 300 to 800 mmol per litre ascorbate anion provided by a mixture of:
(i) ascorbic acid and
(ii) one or more salts of ascorbic acid
the components (i) and (ii) being present in a molar ratio of from 1:4.5 to 1:7.0; and
b) 10 to 200 g per litre polyethylene glycol.
The invention also provides methods and kits associated with, or making use of the solutions, and compositions for the preparation of the solutions.-
公开(公告)号：US20150182501A1
公开(公告)日：2015-07-02
申请号：US14657495
申请日：2015-03-13
申请人： NORGINE BV
发明人： Lucy Clayton , Alasdair Cockett , Mark Christodoulou , Ian Davidson , Lynn Farrag , Marc Halphen , Leighton Jones , Vanik Petrossian , Peter Stein , David Tisi , Alex Ungar , Jeffrey Worthington
IPC分类号： A61K31/375 , A61K47/26 , A61K33/04 , A61K47/18 , A61K31/765 , A61K47/02
CPC分类号： A61K47/26 , A61K9/0053 , A61K9/0095 , A61K9/08 , A61K31/047 , A61K31/375 , A61K31/765 , A61K31/77 , A61K33/04 , A61K33/14 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/183 , Y10S514/892 , A61K2300/00
摘要： The invention provides a colon cleansing solution comprising: a) 300 to 800 mmol per litre ascorbate anion provided by a mixture of: (i) ascorbic acid and (ii) one or more salts of ascorbic acid the components (i) and (ii) being present in a molar ratio of from 1:4.5 to 1:7.0; and b) 10 to 200 g per litre polyethylene glycol. The invention also provides methods and kits associated with, or making use of the solutions, and compositions for the preparation of the solutions.
摘要翻译： 本发明提供了一种结肠清洁溶液，其包含：a）每升抗坏血酸盐阴离子300至800mmol，由以下混合物提供：（i）抗坏血酸和（ii）一种或多种抗坏血酸盐，组分（i）和（ii） 以1:4.5至1:7.0的摩尔比存在; 和b）10至200g /升聚乙二醇。 本发明还提供了与溶液相关联或用于溶液的方法和试剂，以及用于制备溶液的组合物。
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公开(公告)号：US20140228432A1
公开(公告)日：2014-08-14
申请号：US14223127
申请日：2014-03-24
申请人： NORGINE BV
发明人： Lucy Clayton , Alasdair Cockett , Mark Christodoulou , Ian Davidson , Lynn Farrag , Marc Halphen , Leighton Jones , Vanik Petrossian , Peter Stein , David Tisi , Alex Ungar , Jeffrey Worthington
IPC分类号： A61K31/375
CPC分类号： A61K47/26 , A61K9/0053 , A61K9/0095 , A61K9/08 , A61K31/047 , A61K31/375 , A61K31/765 , A61K31/77 , A61K33/04 , A61K33/14 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/183 , Y10S514/892 , A61K2300/00
摘要： The invention provides a colon cleansing solution comprising: a) 300 to 800 mmol per litre ascorbate anion provided by a mixture of: (i) ascorbic acid and (ii) one or more salts of ascorbic acid the components (i) and (ii) being present in a molar ratio of from 1:4.5 to 1:7.0; and b) 10 to 200 g per litre polyethylene glycol. The invention also provides methods an kits associated with, or making use of the solutions, and compositions for the preparation of the solutions.
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公开(公告)号：US10918723B2
公开(公告)日：2021-02-16
申请号：US15605617
申请日：2017-05-25
申请人： NORGINE BV
发明人： Lucy Clayton , Alasdair Cockett , Mark Christodoulou , Ian Davidson , Lynn Farrag , Marc Halphen , Leighton Jones , Vanik Petrossian , Peter Stein , David Tisi , Alex Ungar , Jeffrey Worthington
IPC分类号： A61K47/26 , A61K9/00 , A61K47/10 , A61K31/375 , A61K31/047 , A61K33/04 , A61K33/14 , A61K31/765 , A61K47/02 , A61K9/08 , A61K47/12 , A61K31/77
摘要： The invention provides a colon cleansing solution comprising: a) 300 to 800 mmol per litre ascorbate anion provided by a mixture of: (i) ascorbic acid and (ii) one or more salts of ascorbic acid the components (i) and (ii) being present in a molar ratio of from 1:4.5 to 1:7.0; and b) 10 to 200 g per litre polyethylene glycol. The invention also provides methods an kits associated with, or making use of the solutions, and compositions for the preparation of the solutions.
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