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公开(公告)号:US20150307475A1
公开(公告)日:2015-10-29
申请号:US14653649
申请日:2013-12-17
Applicant: NOVARTIS AG
Inventor: Vikkie Furminger , Owen Rhys Hughes , Darren Mark Legrand , Emily Stanley , Christopher Thomson
IPC: C07D401/12 , A61K31/454
CPC classification number: C07D401/12 , A61K31/4192 , A61K31/445 , A61K31/454 , A61K31/46 , A61K31/496 , A61K31/5375 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D211/26 , C07D211/32 , C07D211/34 , C07D211/58 , C07D211/60 , C07D249/04 , C07D263/38 , C07D265/30 , C07D401/06 , C07D403/06 , C07D403/12 , C07D413/12 , C07D417/12 , C07D451/04
Abstract: The present invention relates to novel compounds of formula (I) (I) that are autotaxin inhibitors, processes for their preparation, pharmaceutical compositions and medicaments containing them and to their use in the treatment of an ATX-dependent or ATX-mediated disease or condition.
Abstract translation: 本发明涉及新型的式(I)(I)化合物,其为自分泌抑素,其制备方法,药物组合物和含有它们的药物及其用于治疗ATX依赖性或ATX介导的疾病或病症 。