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1.5-membered heteroarylcarboxamide derivatives as plasma kallikrein inhibitors 审中-公开
Title translation: 5元杂芳基羧酰胺衍生物作为血浆激肽释放酶抑制剂公开(公告)号:US20140378474A1
公开(公告)日:2014-12-25
申请号:US14371457
申请日:2013-01-25
Applicant: NOVARTIS AG
Inventor: Stefanie Flohr , Christian Markert , Kenji Namoto , Bernard Pirard
IPC: C07D471/04 , C07D401/14 , A61K31/4155 , C07D403/10 , C07D231/14 , C07D413/14 , A61K31/497 , C07D401/06 , A61K31/4439 , C07D403/14 , A61K31/422 , A61K31/4709 , C07D403/12
CPC classification number: C07D471/04 , A61K31/4155 , A61K31/422 , A61K31/4439 , A61K31/4709 , A61K31/497 , C07D231/14 , C07D401/06 , C07D401/14 , C07D403/10 , C07D403/12 , C07D403/14 , C07D413/14
Abstract: The invention relates to a compound of the formula (I) in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.
Abstract translation: 本发明涉及式(I)化合物,其中取代基如说明书中所定义; 以游离形式或盐形式; 作为其制备,用作药物和包含它的药物。