公开(公告)号：US20230365674A1

公开(公告)日：2023-11-16

申请号：US18193581

申请日：2023-03-30

Applicant: NOVARTIS AG

Inventor： John Louis DIENER ,  Lars GADTKE ,  Felix HARTLEPP ,  Tiancen HU ,  Kathrin LADETZKI-BAEHS ,  Michael John ROMANOWSKI ,  Cesare RUSSO ,  Xenia WEZLER ,  Xiaoling XIE

IPC: C07K16/28 ,  A61P9/00 ,  A61K39/395 ,  A61P13/12

CPC classification number: C07K16/28 ,  A61K39/3955 ,  A61P9/00 ,  A61P13/12 ,  C07K16/2869 ,  A61K45/06

Abstract: This disclosure relates to anti-Natriuretic Peptide Receptor 1 (NPR1) antibodies including agonist antibodies which are able to activate the NPR1 receptor, pharmaceutical compositions comprising the same, and methods of treatment comprising the same.

公开(公告)号：US20220356242A1

公开(公告)日：2022-11-10

申请号：US17348949

申请日：2021-06-16

Applicant: NOVARTIS AG

Inventor： John Louis DIENER ,  Lars GADTKE ,  Felix HARTLEPP ,  Tiancen HU ,  Kathrin LADETZKI-BAEHS ,  Michael John ROMANOWSKI ,  Cesare RUSSO ,  Xenia WEZLER ,  Xiaoling XIE

IPC: C07K16/28 ,  A61P9/00 ,  A61K39/395 ,  A61P13/12

Abstract: This disclosure relates to anti-Natriuretic Peptide Receptor 1 (NPR1) antibodies including agonist antibodies which are able to activate the NPR1 receptor, pharmaceutical compositions comprising the same, and methods of treatment comprising the same.