公开(公告)号：US11413270B2

公开(公告)日：2022-08-16

申请号：US16908195

申请日：2020-06-22

Applicant: NOVMETAPHARMA CO., LTD.

Inventor： Heon Jong Lee ,  Hoe Yune Jung ,  In-Kyu Lee ,  Jae-Han Jeon ,  Sung Jin Cho

IPC: A61K31/397 ,  A61K31/495 ,  A61K31/4453 ,  A61K31/5375 ,  A61K31/4025 ,  A61P1/18 ,  A61K31/454 ,  A61K31/407 ,  A61K31/4525 ,  A61K31/403 ,  A61K31/4192 ,  A61K31/396

Abstract: A composition for preventing and/or treating pancreatitis and a method of prevention and/or treatment of pancreatitis are disclosed. The composition include an aryl ethene compound, a pharmaceutically acceptable salt thereof, or a solvate thereof, as an active ingredient. The method includes administering the aryl ethene compound, an isomer, a pharmaceutically acceptable salt thereof, or a solvate thereof, in an effective amount to a subject in need thereof.

公开(公告)号：US11850246B2

公开(公告)日：2023-12-26

申请号：US17393587

申请日：2021-08-04

Applicant: NOVMETAPHARMA CO., LTD.

Inventor： In-Kyu Lee ,  Jae-Han Jeon ,  Dipanjan Chanda ,  Eun Jung Choi ,  Hoe-Yune Jung ,  Heon Jong Lee

IPC: A61K31/495 ,  A61P29/00

CPC classification number: A61K31/495

Abstract: A composition for preventing and/or treating cytokine release syndrome and a method of prevention and/or treatment of cytokine release syndrome are disclosed. The composition includes an aryl ethene compound, a pharmaceutically acceptable salt thereof, or a solvate thereof, as an active ingredient. The method includes administering the aryl ethene compound, an isomer, a pharmaceutically acceptable salt thereof, or a solvate thereof, in an effective amount to a subject in need thereof. The cytokine release syndrome may be caused by virulent infection. The administration of the compound reduces the pre-inflammatory cytokine levels in the subject.

公开(公告)号：US20220362269A1

公开(公告)日：2022-11-17

申请号：US17852774

申请日：2022-06-29

Applicant: NovMetaPharma Co., Ltd.

Inventor： Heon Jong LEE ,  Heo Yune Jung ,  In-Kyu Lee ,  Jae-Han Jeon ,  Sung Jin Cho ,  Jina Kim ,  Hayoung Hwang ,  Yong Hyun Jeon ,  Jungwook Chin

IPC: A61K31/695 ,  A61K31/495 ,  A61K31/4453 ,  A61K31/5375 ,  A61K31/40 ,  A61K31/396 ,  A61K31/397 ,  A61K31/454 ,  A61K31/4025 ,  A61K31/407 ,  A61K31/443 ,  A61K31/403 ,  A61K31/433 ,  A61P1/18

Abstract: A composition for preventing and/or treating pancreatitis and a method of prevention and/or treatment of pancreatitis are disclosed. The composition include an aryl ethene compound, a pharmaceutically acceptable salt thereof, or a solvate thereof, as an active ingredient. Also disclosed is a use of the aryl ethene compound, a pharmaceutically acceptable salt thereof, or a solvate thereof, in manufacturing a medicament for preventing and/or treating pancreatitis or for treating one or more symptoms of pancreatitis in a patient. The method of prevention and/or treatment of pancreatitis includes administering the aryl ethene compound, an isomer, a pharmaceutically acceptable salt thereof, or a solvate thereof, in an effective amount to a subject in need thereof.