公开(公告)号：US3716578A

公开(公告)日：1973-02-13

申请号：US3716578D

申请日：1970-03-18

Applicant: NOVO TERAPEUTISK LABOR AS

Inventor： JOHNK P

IPC: C07C69/145 ,  C07D309/12 ,  C07C69/02

CPC classification number: C07D309/12 ,  C07C2603/26

Abstract: IN WHICH R is hydrogen or OR1; R1 is hydrogen, benzyl, lower alkyl or cycloalkyl; R2 is hydrogen, lower alkyl, cycloalkyl, cycloalkyl containing a hetero atom, or OCR3; R3 is hydrogen, lower alkyl or CH2SO2X; X is chlorine, OR4, or OMe; R4 is hydrogen or lower alkyl; R5 and R6 are hydrogen or lower alkyl, or R5 and R6 together with the attached N-atom form a heterocyclic ring; and Me is an alkali metal or an earth alkali metal atom, useful anti-fertility compositions for oral administration, as well as processes for their production.

Novel hexahydrophenanthrene derivatives of the general formula

Abstract translation: 新型的六氢菲衍生物，其通式为：其中R为氢或OR 1; R1是氢，苄基，低级烷基或环烷基; R2是氢，低级烷基，环烷基，含有杂原子的环烷基，或OCR3; R3是氢，低级烷基或CH2SO2X; X是氯，OR4或OMe; R4是氢或低级烷基; R5和R6是氢或低级烷基，或R5和R6与连接的N-原子一起形成杂环; Me是碱金属或碱土金属原子，用于口服给药的有用的抗生育组合物，以及它们的生产方法。