公开(公告)号：US20230293886A1

公开(公告)日：2023-09-21

申请号：US18111353

申请日：2023-02-17

Applicant: NSE Products, Inc.

Inventor： Dale G. Kern ,  Ganesh Diwakar

IPC: A61N1/32 ,  A61N1/04

CPC classification number: A61N1/325 ,  A61N1/0428 ,  A61N1/0476

Abstract: A method includes applying one or more electrodes to the skin or skin surface of a subject, applying a voltage or current signal to the skin surface via one or more of the electrodes, and modulating the signal to maintain treatment efficacy, or so that the power output can be charge balanced, or both. An agent can be applied to the skin surface during a treatment period defined after the voltage or current signal is applied. Permeability of the skin to one or more components of the agent is enhanced or increased during the treatment period, responsive to the modulated power output. A device for performing the method is also provided.