公开(公告)号：US07495222B2

公开(公告)日：2009-02-24

申请号：US11751372

申请日：2007-05-21

申请人： Nan Zhang ,  Matthias J. Schmand ,  Niraj K. Doshi

发明人： Nan Zhang ,  Matthias J. Schmand ,  Niraj K. Doshi

IPC分类号： G01T1/20

CPC分类号： G01T1/1642 ,  G01T1/1647

摘要： A system for multiplexing photodetector signals from a scintillation detector. The system includes a detector module having a number of scintillator blocks, each scintillator block having a number of photosensors, and a number of multiplexing circuits. Each multiplexing circuit includes a number of inputs, a signal polarity inverter and at least one differential output attached to the signal polarity inverter. The multiplexing system inverts the polarity of preselected signals from the photosensors and selectively combines signals of different polarities to calculate event positioning and total energy.

摘要翻译： 一种用于复用来自闪烁检测器的光检测器信号的系统。 该系统包括具有多个闪烁体块的检测器模块，每个闪烁体块具有多个光电传感器，以及多个复用电路。 每个多路复用电路包括多个输入端，信号极性反相器和附加到信号极性反相器的至少一个差分输出。 复用系统将来自光电传感器的预选信号的极性反转，并且选择性地组合不同极性的信号以计算事件定位和总能量。

公开(公告)号：US09086492B2

公开(公告)日：2015-07-21

申请号：US11753067

申请日：2007-05-24

申请人： Nan Zhang ,  Matthias J. Schmand ,  Niraj K. Doshi ,  Michael D. Loope

发明人： Nan Zhang ,  Matthias J. Schmand ,  Niraj K. Doshi ,  Michael D. Loope

IPC分类号： G01T1/00 ,  G01T1/164

CPC分类号： G01T1/1642 ,  G01T1/208

摘要： A scintillation detector including one or more photomultiplier tubes, a scintillation block optically attached to the photomultiplier tubes, and a DC-coupled bleeder circuit combining outputs of dynodes of the photomultipliers to provide a DC-coupled dynode output together with a DC-coupled anode output of the photomultiplier tubes. The DC-coupled bleeder circuit includes a RF transformer. A positive high voltage supply also can be used together with a DC-coupled bleeder circuit for the anode outputs.

摘要翻译： 闪烁检测器，包括一个或多个光电倍增管，与光电倍增管光学连接的闪烁块，以及组合光电倍增管的倍增电极输出的DC耦合泄放电路，以提供DC耦合的倍增电极输出以及直流耦合的阳极输出 的光电倍增管。 直流耦合放电电路包括RF变压器。 阳极高压电源也可以与阳极输出的直流耦合泄放电路一起使用。

公开(公告)号：US07579599B2

公开(公告)日：2009-08-25

申请号：US11941562

申请日：2007-11-16

申请人： Nan Zhang ,  Volker Matschl ,  Niraj K. Doshi ,  Matthias J. Schmand

发明人： Nan Zhang ,  Volker Matschl ,  Niraj K. Doshi ,  Matthias J. Schmand

IPC分类号： G01T1/164

CPC分类号： A61B6/037 ,  A61B6/56

摘要： A medical device with a high voltage connection line for carrying a high DC supply voltage has a control unit generating said high DC supply voltage which is fed through a first AC block unit to said high voltage connection line and generating a digital control signal fed through a first AC coupling unit to said high voltage connection line, and a remotely located unit a second AC block unit coupled to said high voltage connection line for receiving said high DC supply voltage and a second AC coupling unit coupled to said high voltage connection line for receiving said digital control signal.

摘要翻译： 具有用于承载高直流电源电压的高压连接线的医疗装置具有产生所述高直流电源电压的控制单元，所述高直流电源电压通过第一AC块单元馈送到所述高压连接线，并产生通过 第一AC耦合单元连接到所述高压连接线，以及远程定位单元，耦合到所述高压连接线的第二AC块单元，用于接收所述高DC电源电压;以及第二AC耦合单元，耦合到所述高压连接线，用于接收 所述数字控制信号。

公开(公告)号：US20080290282A1

公开(公告)日：2008-11-27

申请号：US11753067

申请日：2007-05-24

申请人： Nan Zhang ,  Matthias J. Schmand ,  Niraj K. Doshi ,  Michael D. Loope

发明人： Nan Zhang ,  Matthias J. Schmand ,  Niraj K. Doshi ,  Michael D. Loope

IPC分类号： G01T1/20

CPC分类号： G01T1/1642 ,  G01T1/208

摘要： A scintillation detector including one or more photomultiplier tubes, a scintillation block optically attached to the photomultiplier tubes, and a DC-coupled bleeder circuit combining outputs of dynodes of the photomultipliers to provide a DC-coupled dynode output together with a DC-coupled anode output of the photomultiplier tubes. The DC-coupled bleeder circuit includes a RF transformer. A positive high voltage supply also can be used together with a DC-coupled bleeder circuit for the anode outputs.

摘要翻译： 闪烁检测器，包括一个或多个光电倍增管，与光电倍增管光学连接的闪烁块，以及组合光电倍增管的倍增电极输出的DC耦合泄放电路，以提供DC耦合的倍增电极输出以及直流耦合的阳极输出 的光电倍增管。 直流耦合放电电路包括RF变压器。 阳极高压电源也可以与阳极输出的直流耦合泄放电路一起使用。

公开(公告)号：US09006664B2

公开(公告)日：2015-04-14

申请号：US13115220

申请日：2011-05-25

申请人： Nan Zhang ,  Niraj K. Doshi ,  Matthias J. Schmand

发明人： Nan Zhang ,  Niraj K. Doshi ,  Matthias J. Schmand

IPC分类号： G01T1/20

CPC分类号： G01T1/2018

摘要： Signals generated by radiation sensors can be encoded to reduce the number of cables needed to transport information from a nuclear imaging apparatus to a processor for reconstruction. For example, signals from 16 radiation sensors can be encoded into three signals: T (top), L (left), and E (energy). This method of encoding signals can be capable of substantially reducing the number of signals, thereby reducing costs. In addition, reducing the number of signals could improve system timing performance by eliminating cable time-skew and facilitate the filter design by downgrading the circuit accuracy requirements such as group-delay error and filter signal skews.

摘要翻译： 可以编码由辐射传感器产生的信号以减少将信息从核成像设备传输到处理器以进行重建所需的电缆数量。 例如，来自16个辐射传感器的信号可以被编码成三个信号：T（上），L（左）和E（能量）。 这种编码信号的方法能够显着减少信号的数量，从而降低成本。 此外，减少信号数量可以通过消除电缆时间偏移来提高系统定时性能，并通过降低电路精度要求（如组延迟误差和滤波器信号偏移）来促进滤波器设计。

公开(公告)号：US20120212355A1

公开(公告)日：2012-08-23

申请号：US13115220

申请日：2011-05-25

申请人： Nan Zhang ,  Niraj K. Doshi ,  Matthias J. Schmand

发明人： Nan Zhang ,  Niraj K. Doshi ,  Matthias J. Schmand

IPC分类号： H03M7/00 ,  G01T1/20 ,  G01T1/00

CPC分类号： G01T1/2018

摘要： Signals generated by radiation sensors can be encoded to reduce the number of cables needed to transport information from a nuclear imaging apparatus to a processor for reconstruction. For example, signals from 16 radiation sensors can be encoded into three signals: T (top), L (left), and E (energy). This method of encoding signals can be capable of substantially reducing the number of signals, thereby reducing costs. In addition, reducing the number of signals could improve system timing performance by eliminating cable time-skew and facilitate the filter design by downgrading the circuit accuracy requirements such as group-delay error and filter signal skews.

摘要翻译： 可以编码由辐射传感器产生的信号以减少将信息从核成像设备传输到处理器以进行重建所需的电缆数量。 例如，来自16个辐射传感器的信号可以被编码成三个信号：T（上），L（左）和E（能量）。 这种编码信号的方法能够显着减少信号的数量，从而降低成本。 此外，减少信号数量可以通过消除电缆时间偏移来提高系统定时性能，并通过降低电路精度要求（如组延迟误差和滤波器信号偏移）来促进滤波器设计。

公开(公告)号：US20090072151A1

公开(公告)日：2009-03-19

申请号：US11941562

申请日：2007-11-16

申请人： Nan Zhang ,  Volker Matschl ,  Niraj K. Doshi ,  Matthias J. Schmand

发明人： Nan Zhang ,  Volker Matschl ,  Niraj K. Doshi ,  Matthias J. Schmand

IPC分类号： G01T1/164 ,  H04B3/54

CPC分类号： A61B6/037 ,  A61B6/56

摘要： A medical device with a high voltage connection line for carrying a high DC supply voltage has a control unit generating said high DC supply voltage which is fed through a first AC block unit to said high voltage connection line and generating a digital control signal fed through a first AC coupling unit to said high voltage connection line, and a remotely located unit a second AC block unit coupled to said high voltage connection line for receiving said high DC supply voltage and a second AC coupling unit coupled to said high voltage connection line for receiving said digital control signal.

摘要翻译： 具有用于承载高直流电源电压的高压连接线的医疗装置具有产生所述高直流电源电压的控制单元，所述高直流电源电压通过第一AC块单元馈送到所述高压连接线，并产生通过 第一AC耦合单元连接到所述高压连接线，以及远程定位单元，耦合到所述高压连接线的第二AC块单元，用于接收所述高DC电源电压;以及第二AC耦合单元，耦合到所述高压连接线，用于接收 所述数字控制信号。

公开(公告)号：US20130062525A1

公开(公告)日：2013-03-14

申请号：US13229797

申请日：2011-09-12

申请人： James Frank Caruba ,  Niraj K. Doshi ,  John W. Young ,  Nan Zhang

发明人： James Frank Caruba ,  Niraj K. Doshi ,  John W. Young ,  Nan Zhang

IPC分类号： G01T1/20 ,  G01T1/164

CPC分类号： G01T1/1648

摘要： Using standard or “off the shelf” cable to interconnect between the PET block detector and the detector circuit may save substantial costs given the number of PMTs in a PET system. Given space constraints, simple maintenance with reduced risk of disturbing cabling is desired, making ongoing use of standard cabling without adding further cabling desired. To implement digital gain control, a further communication is provided between the PET detector block and the detector circuit. Since the standard cable may not have additional wires for such communications and to reduce timing degradation, the PMT signals are combined, such as generating position and energy signals at the PET detector block. The four PMT signals are reduced to three signals without reduction in function, allowing a fourth twisted pair of wires in a CAT5 cable to be used for digital gain control.

摘要翻译： 使用标准或现货电缆在PET块检测器和检测器电路之间进行互连可以节省大量成本，因为PET系统中PMT的数量。 鉴于空间限制，需要简单的维护，减少干扰布线的风险，不断增加布线需求，不断使用标准布线。 为了实现数字增益控制，在PET检测器块和检测器电路之间提供进一步的通信。 由于标准电缆可能没有用于这种通信的附加电线并且减少定时劣化，所以组合PMT信号，例如在PET检测器块处产生位置和能量信号。 四个PMT信号减少到三个信号，而不会降低功能，允许CAT5电缆中的第四根双绞线用于数字增益控制。

公开(公告)号：US08735836B2

公开(公告)日：2014-05-27

申请号：US13229797

申请日：2011-09-12

申请人： James Frank Caruba ,  Niraj K Doshi ,  John W Young ,  Nan Zhang

发明人： James Frank Caruba ,  Niraj K Doshi ,  John W Young ,  Nan Zhang

IPC分类号： G01T1/164

CPC分类号： G01T1/1648

摘要： Using standard or “off the shelf” cable to interconnect between the PET block detector and the detector circuit may save substantial costs given the number of PMTs in a PET system. Given space constraints, simple maintenance with reduced risk of disturbing cabling is desired, making ongoing use of standard cabling without adding further cabling desired. To implement digital gain control, a further communication is provided between the PET detector block and the detector circuit. Since the standard cable may not have additional wires for such communications and to reduce timing degradation, the PMT signals are combined, such as generating position and energy signals at the PET detector block. The four PMT signals are reduced to three signals without reduction in function, allowing a fourth twisted pair of wires in a CAT5 cable to be used for digital gain control.

摘要翻译： 使用标准或“现成”电缆在PET块检测器和检测器电路之间进行互连可以节省大量成本，因为PET系统中PMT的数量。 鉴于空间限制，需要简单的维护，减少干扰布线的风险，不断增加布线需求，不断使用标准布线。 为了实现数字增益控制，在PET检测器块和检测器电路之间提供进一步的通信。 由于标准电缆可能没有用于这种通信的附加电线并且减少定时劣化，所以组合PMT信号，例如在PET检测器块处产生位置和能量信号。 四个PMT信号减少到三个信号而不减少功能，允许CAT5电缆中的第四根双绞线用于数字增益控制。

公开(公告)号：US09091771B2

公开(公告)日：2015-07-28

申请号：US13539915

申请日：2012-07-02

申请人： Debora Henseler ,  Ronald Grazioso ,  Nan Zhang ,  Matthias J. Schmand ,  Sanghee Cho

发明人： Debora Henseler ,  Ronald Grazioso ,  Nan Zhang ,  Matthias J. Schmand ,  Sanghee Cho

IPC分类号： G01T1/29 ,  A61B6/03 ,  G01T1/00 ,  A61B6/00

CPC分类号： G01T1/2985 ,  A61B6/00 ,  A61B6/037 ,  G01T1/00

摘要： A system and method are provided for determining the onset of gamma interactions for positron emission tomography (PET) imaging more accurately than with existing techniques. The timing of a sequence of primary trigger events is obtained and used to determine a weighted combination, which mixes the timing information from the various primary trigger events to compute an overall event trigger timing with improved time resolution. Numerical simulations demonstrate that the invention improves time resolution by approximately 10% over state-of-the-art methods. This improved time resolution directly benefits the imaging performance of the PET scanner, especially in time-of-flight (TOF) mode, where a high time resolution directly translates to a reduction in image noise at the same dose—or, alternatively, a reduction of dose to the patient or scan time for the same image quality.

摘要翻译： 提供了一种系统和方法，用于比现有技术更准确地确定正电子发射断层摄影（PET）成像的γ相互作用的发生。 获得主要触发事件序列的定时并用于确定加权组合，其混合来自各种主要触发事件的定时信息以通过改进的时间分辨率计算总体事件触发时序。 数值模拟表明，本发明使用最先进的方法将时间分辨率提高约10％。 这种改进的时间分辨率直接有利于PET扫描仪的成像性能，特别是在飞行时间（TOF）模式下，其中高时间分辨率直接转换为以相同剂量降低图像噪声，或者替代地，减少 给予患者剂量或扫描时间相同的图像质量。