公开(公告)号：US11773045B2

公开(公告)日：2023-10-03

申请号：US18024730

申请日：2022-01-19

Applicant: Nanjing Tech University

Inventor： Yufeng Li ,  Hongjun Zhu ,  Hongfei Ma ,  Hongzhong Bu ,  Jieqing Wu ,  Jiefan Gu ,  Jiwei Chen ,  Haoyue Zhang ,  Chen Wang

IPC: C07C51/16 ,  C07C45/32 ,  C07C201/12 ,  C07C253/30

CPC classification number: C07C51/16 ,  C07C45/32 ,  C07C201/12 ,  C07C253/30

Abstract: Provided is a photo-oxidation reaction of benzylic C—H bonds of an aromatic compound under the catalysis of an acid catalyst. The method aims to synthesize aromatic acids and acetophenones. The acid catalyst is one of Bronsted acids, including one or a mixture of two or more selected from the group consisting of hydrochloric acid, phosphoric acid, sulfuric acid, p-toluenesulfonic acid, methanesulfonic acid, trifluoromethanesulfonic acid, trifluoroacetic acid, and potassium hydrogen sulfate, as well as N-propylsulfonate pyridinium hydrogensulfate, N-butylsulfonate pyridinium hydrogensulfate, N-propylsulfonate pyridinium trifluoromethanesulfonate, N-butylsulfonate pyridinium trifluoromethanesulfonate, N-propylsulfonate pyridinium tetrafluoroborate, and N-butylsulfonate pyridinium tetrafluoroborate. The oxidation reaction is conducted under mild conditions (normal temperature and pressure) using air or oxygen as the oxidant in the presence of recyclable catalyst and solvent.

公开(公告)号：US20230242470A1

公开(公告)日：2023-08-03

申请号：US18024730

申请日：2022-01-19

Applicant: Nanjing Tech University

Inventor： Yufeng Li ,  Hongjun Zhu ,  Hongfei Ma ,  Hongzhong Bu ,  Jieqing Wu ,  Jiefan Gu ,  Jiwei Chen ,  Haoyue Zhang ,  Chen Wang

IPC: C07C51/16 ,  C07C45/32 ,  C07C201/12 ,  C07C253/30

CPC classification number: C07C51/16 ,  C07C45/32 ,  C07C201/12 ,  C07C253/30

Abstract: Provided is a photo-oxidation reaction of benzylic C—H bonds of an aromatic compound under the catalysis of an acid catalyst. The method aims to synthesize aromatic acids and acetophenones. The acid catalyst is one of Bronsted acids, including one or a mixture of two or more selected from the group consisting of hydrochloric acid, phosphoric acid, sulfuric acid, p-toluenesulfonic acid, methanesulfonic acid, trifluoromethanesulfonic acid, trifluoroacetic acid, and potassium hydrogen sulfate, as well as N-propylsulfonate pyridinium hydrogensulfate, N-butylsulfonate pyridinium hydrogensulfate, N-propylsulfonate pyridinium trifluoromethanesulfonate, N-butylsulfonate pyridinium trifluoromethanesulfonate, N-propylsulfonate pyridinium tetrafluoroborate, and N-butylsulfonate pyridinium tetrafluoroborate. The oxidation reaction is conducted under mild conditions (normal temperature and pressure) using air or oxygen as the oxidant in the presence of recyclable catalyst and solvent.